Dooley MA.Clinical and laboratory features of lupus nephritis
... Lupus nephritis (LN) is one of the most serious complications of systemic lupus erythematosus (SLE). The true prevalence of clinical lupus nephritis in persons with SLE is probably around 50%, being higher in certain ethnic groups and in children. It was hypothesized that intrarenal B cells form par ...
... Lupus nephritis (LN) is one of the most serious complications of systemic lupus erythematosus (SLE). The true prevalence of clinical lupus nephritis in persons with SLE is probably around 50%, being higher in certain ethnic groups and in children. It was hypothesized that intrarenal B cells form par ...
Asthma
... their serious side effects. Short-term side effects include increased appetite, weight gain, hypertension, and fluid retention. Over the long-term, corticosteroids may cause osteoporosis, cataracts, and impaired immune response. These side effects usually preclude the use of corticosteroids for long ...
... their serious side effects. Short-term side effects include increased appetite, weight gain, hypertension, and fluid retention. Over the long-term, corticosteroids may cause osteoporosis, cataracts, and impaired immune response. These side effects usually preclude the use of corticosteroids for long ...
Adrenal Cortical Insufficiency—a Life Threatening Illness With
... treatment of adrenal cortical insufficiency—Although Thomas Addison characterized the clinical picture of his namesake disease or primary adrenal cortical insufficiency already in 1855 (e7), it was not until 1936 with the discovery of cortisol by Kendall, Wintersteiner, and Reichenstein and the subs ...
... treatment of adrenal cortical insufficiency—Although Thomas Addison characterized the clinical picture of his namesake disease or primary adrenal cortical insufficiency already in 1855 (e7), it was not until 1936 with the discovery of cortisol by Kendall, Wintersteiner, and Reichenstein and the subs ...
Chest radiography and pneumonia in primary care: diagnostic yield and
... radiography (CXR) in primary-care patients suspected of pneumonia. In total, 192 patients with a clinical suspicion of pneumonia aged o18 yrs were referred by their general practitioner (GP) for CXR to one of the three participating hospitals in the Netherlands. All GPs were asked to complete a stan ...
... radiography (CXR) in primary-care patients suspected of pneumonia. In total, 192 patients with a clinical suspicion of pneumonia aged o18 yrs were referred by their general practitioner (GP) for CXR to one of the three participating hospitals in the Netherlands. All GPs were asked to complete a stan ...
References
... Between June 2008 and July 2012, 512 eligible HCWs and HHCs with known BCG vaccination status were identified (263 HCWs, 166 HHCs and 83 with unclassified exposure). The exposure classification was assigned through a questionnaire, but this information was not captured in the initial phase of the st ...
... Between June 2008 and July 2012, 512 eligible HCWs and HHCs with known BCG vaccination status were identified (263 HCWs, 166 HHCs and 83 with unclassified exposure). The exposure classification was assigned through a questionnaire, but this information was not captured in the initial phase of the st ...
dr sarah myhill, upper weston, llangunllo, knighton, powys
... work at 100% efficiency. The liver is a vital organ for detoxifying poisons (which may be natural plant toxins or artificial chemicals). If it does not detoxify well, poisons or toxins accumulate in the body and cause disease. ...
... work at 100% efficiency. The liver is a vital organ for detoxifying poisons (which may be natural plant toxins or artificial chemicals). If it does not detoxify well, poisons or toxins accumulate in the body and cause disease. ...
Pemphigus vulgaris - British Association of Dermatologists
... Pemphigus vulgaris affects both males and females equally. It can start at any age but is most common in adults usually between 50-60 years old. It affects people of all races but is more common in some than others, for example in people of Jewish origin. Pemphigus vulgaris is not an infection: it c ...
... Pemphigus vulgaris affects both males and females equally. It can start at any age but is most common in adults usually between 50-60 years old. It affects people of all races but is more common in some than others, for example in people of Jewish origin. Pemphigus vulgaris is not an infection: it c ...
Tong, LF, Balakrishan G, Kochan JP, et al. Assessment of
... All antigens initially elicit the production of IgM antibodies against an injected or inhaled allergen. With repeated exposure, the antigen may stimulate an event known as class switching, whereby the constant portion of the antibody will “switch” to another class (i.e., IgG, IgA, or IgE). The new a ...
... All antigens initially elicit the production of IgM antibodies against an injected or inhaled allergen. With repeated exposure, the antigen may stimulate an event known as class switching, whereby the constant portion of the antibody will “switch” to another class (i.e., IgG, IgA, or IgE). The new a ...
cancer vaccines: between the idea and the reality
... antigens, such as cyclin B1 (REF. 21), or one of many cancer-germ-cell antigens that are specifically found in breast tumours22. Similarly, there are a large number of antigens available for melanoma vaccines. Extensive studies have been carried out with them in animal models and in clinical trials2 ...
... antigens, such as cyclin B1 (REF. 21), or one of many cancer-germ-cell antigens that are specifically found in breast tumours22. Similarly, there are a large number of antigens available for melanoma vaccines. Extensive studies have been carried out with them in animal models and in clinical trials2 ...
CANCER VACCINES: BETWEEN THE IDEA AND THE REALITY Olivera J. Finn
... antigens, such as cyclin B1 (REF. 21), or one of many cancer-germ-cell antigens that are specifically found in breast tumours22. Similarly, there are a large number of antigens available for melanoma vaccines. Extensive studies have been carried out with them in animal models and in clinical trials2 ...
... antigens, such as cyclin B1 (REF. 21), or one of many cancer-germ-cell antigens that are specifically found in breast tumours22. Similarly, there are a large number of antigens available for melanoma vaccines. Extensive studies have been carried out with them in animal models and in clinical trials2 ...
Treatment-dependent Loss of Polyfunctional CD8+ T
... of acute rejection episodes (7–14). Accordingly, the use of appropriate immunosuppressive (IS) regimens in this setting is a matter of debate more so than the generally well tolerated ART. In particular, IS regimens including thymoglobulin (ATG), have been associated with an accelerated long-term CD ...
... of acute rejection episodes (7–14). Accordingly, the use of appropriate immunosuppressive (IS) regimens in this setting is a matter of debate more so than the generally well tolerated ART. In particular, IS regimens including thymoglobulin (ATG), have been associated with an accelerated long-term CD ...
K Kawasaki disease: Etiology, pathogenesis, and treatment
... and control patients with other febrile illnesses. During convalescence, the proportion of Vβ2+ and Vβ8.1+ T cells returned to normal levels. • Yamashiro 199641—the occurrence of Vβ2+T cells was found to be selectively increased in the small intestinal mucosa of 12 patients with acute KD compared to ...
... and control patients with other febrile illnesses. During convalescence, the proportion of Vβ2+ and Vβ8.1+ T cells returned to normal levels. • Yamashiro 199641—the occurrence of Vβ2+T cells was found to be selectively increased in the small intestinal mucosa of 12 patients with acute KD compared to ...
Hemophagocytosis in adults (Hemophagocytic Syndrome) Brady Miller Hematology Oncology Fellow
... Secondary (acquired) HLH – Occurs in all age groups. No published data on incidence or age distribution. – Underlying conditions include infections, autoimmune diseases, malignancies, and immune suppression/organ transplantation. – As in primary HLH, the cytoxic activity of the NK and CTLs are bloc ...
... Secondary (acquired) HLH – Occurs in all age groups. No published data on incidence or age distribution. – Underlying conditions include infections, autoimmune diseases, malignancies, and immune suppression/organ transplantation. – As in primary HLH, the cytoxic activity of the NK and CTLs are bloc ...
Botulinum toxin for treatment of glandular hypersecretory disorders
... Frey’s syndrome is an uncommon disorder that arises from injury to or surgery near the parotid gland, damaging the secretory parasympathetic fibres of the facial nerve. It is believed that after injury these fibres regenerate and miscommunication occurs between them and the severed postganglionic sy ...
... Frey’s syndrome is an uncommon disorder that arises from injury to or surgery near the parotid gland, damaging the secretory parasympathetic fibres of the facial nerve. It is believed that after injury these fibres regenerate and miscommunication occurs between them and the severed postganglionic sy ...
NASZA DERMATOLOGIAOnline OUR DERMATOLOGYOnline
... endomysial antigens have been found in most patients, as well as antibodies to tissue transglutaminase (tTG) [3]. Moreover, DH is also associated against eTG; eTG represents a member of the same protein family as tTG. Further, tissue transglutaminase has been described as the primary autoantigen of ...
... endomysial antigens have been found in most patients, as well as antibodies to tissue transglutaminase (tTG) [3]. Moreover, DH is also associated against eTG; eTG represents a member of the same protein family as tTG. Further, tissue transglutaminase has been described as the primary autoantigen of ...
Induction of IgA Circulating Immune Complexes after
... test units). By definition, values greater than 2 test units above this mean are considered to be elevated. Assay variability of the Raji cell IgA eIe which is clearly above the normal range, and signifitest on an individual day was established by running the same sample cantly different from base l ...
... test units). By definition, values greater than 2 test units above this mean are considered to be elevated. Assay variability of the Raji cell IgA eIe which is clearly above the normal range, and signifitest on an individual day was established by running the same sample cantly different from base l ...
Chapter 4: Adrenal Disorders
... (preferably at age 6 to 18 months). When necessary, vaginoplasty is usually performed in late adolescence because routine vaginal dilation is required to maintain a patent vagina. Adrenalectomy Bilateral adrenalectomy has been reported as an experimental treatment of patients with severe disease who ...
... (preferably at age 6 to 18 months). When necessary, vaginoplasty is usually performed in late adolescence because routine vaginal dilation is required to maintain a patent vagina. Adrenalectomy Bilateral adrenalectomy has been reported as an experimental treatment of patients with severe disease who ...
Introduction - Philsci
... everything that is different from itself, that is, everything that does not come from the 'inside'. According to the CC, an effector immune response is indeed due to an antigenic difference, but not a difference between the endogenous (self) and the exogenous (nonself). The CC goes back to the antig ...
... everything that is different from itself, that is, everything that does not come from the 'inside'. According to the CC, an effector immune response is indeed due to an antigenic difference, but not a difference between the endogenous (self) and the exogenous (nonself). The CC goes back to the antig ...
New Biologic Drugs: Evaluation and Treatment of Hypersensitivity
... and activator of transcription 6-deficient mast cells by suboptimal doses of antigen. Ann Allergy Asthma Immunol 2005; 94(5):575. Castells MC et al. Hypersensitivity Reactions to chemotherapy:Outcomes and safety of rapid desensitizations in 413 cases J All Clin Immunol 122:574, 2008 Breslow R et al ...
... and activator of transcription 6-deficient mast cells by suboptimal doses of antigen. Ann Allergy Asthma Immunol 2005; 94(5):575. Castells MC et al. Hypersensitivity Reactions to chemotherapy:Outcomes and safety of rapid desensitizations in 413 cases J All Clin Immunol 122:574, 2008 Breslow R et al ...
Hemophilia and oral health Ruta Zaliuniene, Vytaute Peciuliene
... VIII and occurs in 80-85% of patients and has an incidence of 1: 5 000 in the male population (12). Hemophilia B (or Christmas disease) is a deficiency of factor IX and is diagnosed 10 times less frequent than hemophilia A. It accounts 10-15% of hemophilia cases with the incidence of 1:15 000 (13, 1 ...
... VIII and occurs in 80-85% of patients and has an incidence of 1: 5 000 in the male population (12). Hemophilia B (or Christmas disease) is a deficiency of factor IX and is diagnosed 10 times less frequent than hemophilia A. It accounts 10-15% of hemophilia cases with the incidence of 1:15 000 (13, 1 ...
Drug Hypersensitivity
... 1. Introduction The in vitro diagnosis of allergic reactions to drugs is of particular interest to clinicians, as neither the clinical history nor the in vivo tests are fully conclusive. In addition, these tests may often be associated with risk, as occurs with the drug provocation test. Various dif ...
... 1. Introduction The in vitro diagnosis of allergic reactions to drugs is of particular interest to clinicians, as neither the clinical history nor the in vivo tests are fully conclusive. In addition, these tests may often be associated with risk, as occurs with the drug provocation test. Various dif ...
Clinical Approach to Isolated Splenomegaly
... it is palpable more than 8 cm below the left costal margin or its drained weight is 1000 g. The vast majority of such patients will have a hematological diseases i.e. nonHodgkin’s lymphoma, chronic lymphocytic leukemia, hairy cell leukemia, chronic myelogenous leukemia, myelofibrosis with myeloid me ...
... it is palpable more than 8 cm below the left costal margin or its drained weight is 1000 g. The vast majority of such patients will have a hematological diseases i.e. nonHodgkin’s lymphoma, chronic lymphocytic leukemia, hairy cell leukemia, chronic myelogenous leukemia, myelofibrosis with myeloid me ...
Cytokine responses in human Lyme borreliosis
... Although Lyme borreliosis is treatable with antibiotics and the causative spirochete has not been shown to be resistant to drugs, some patients do not recover completely. They have persistent symptoms and are diagnosed with chronic or persistent Lyme borreliosis. The mechanism behind the lingering s ...
... Although Lyme borreliosis is treatable with antibiotics and the causative spirochete has not been shown to be resistant to drugs, some patients do not recover completely. They have persistent symptoms and are diagnosed with chronic or persistent Lyme borreliosis. The mechanism behind the lingering s ...
Enhancement of Epithelial Barrier Function by Probiotics
... but the altered route of passage can also significantly alter the immunogenicity of the microbial antigen. Increased gut permeability is associated with several different human diseases, including inflammatory bowel disease [51], graft vs host disease[52], type 1 diabetes [53], and celiac disease [5 ...
... but the altered route of passage can also significantly alter the immunogenicity of the microbial antigen. Increased gut permeability is associated with several different human diseases, including inflammatory bowel disease [51], graft vs host disease[52], type 1 diabetes [53], and celiac disease [5 ...
Irritable Bowel Syndrome A Clinical Review
... tinct pathophysiology that present with similar symptoms. During the past 40 years, a number of factors that contribute to the pathophysiology of IBS have emerged. Traditionally, the pathogenesis of IBS has focused on abnormalities in motility, visceral sensation, braingut interaction, and psychosoc ...
... tinct pathophysiology that present with similar symptoms. During the past 40 years, a number of factors that contribute to the pathophysiology of IBS have emerged. Traditionally, the pathogenesis of IBS has focused on abnormalities in motility, visceral sensation, braingut interaction, and psychosoc ...