Chapter 1 - Research Explorer
... the main limitation of these studies is the fact that subjects were selected based on their twinship rather than their periodontal condition, resulting in populations with mild periodontal breakdown. Genetic polymorphisms in a candidate gene approach have been explored as risk predictors for periodo ...
... the main limitation of these studies is the fact that subjects were selected based on their twinship rather than their periodontal condition, resulting in populations with mild periodontal breakdown. Genetic polymorphisms in a candidate gene approach have been explored as risk predictors for periodo ...
Prescribing Information
... This indication is approved under accelerated approval based on tumor response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials. (1.1) • Metastatic non-small cell lung cancer who have ...
... This indication is approved under accelerated approval based on tumor response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials. (1.1) • Metastatic non-small cell lung cancer who have ...
Enhanced T cell activation in Plasmodium falciparum malaria
... Although the validated marker of CD8+ T cell activation is the co-expression of CD38 and HLA-DR, activated cells were identified by detecting CD38 on CD8+ T cells and HLA-DR on CD3+ T cells. These molecules were used as surrogates for the validated marker (Douek et al. 2009). HLA-DR positivity was d ...
... Although the validated marker of CD8+ T cell activation is the co-expression of CD38 and HLA-DR, activated cells were identified by detecting CD38 on CD8+ T cells and HLA-DR on CD3+ T cells. These molecules were used as surrogates for the validated marker (Douek et al. 2009). HLA-DR positivity was d ...
A new vision of immunity: homeostasis of the superorganism
... basis of pathogen recognition. Recently, it was suggested that pathogenic microbes are recognized by “patterns of pathogenesis”,9 or POPs. Rather than by its structure, a pathogen would be defined by its characteristic behavior. A first POP is growth, as pathogens are able to grow in their host upon ...
... basis of pathogen recognition. Recently, it was suggested that pathogenic microbes are recognized by “patterns of pathogenesis”,9 or POPs. Rather than by its structure, a pathogen would be defined by its characteristic behavior. A first POP is growth, as pathogens are able to grow in their host upon ...
Nutrition in Clinical Practice - American Society for Parenteral and
... [DPG]) with inhibition of fat metabolism. This results in hypophosphatemia, the hallmark sign of RS. Additional mechanisms identified as contributing to low serum phosphorus concentrations include preexisting low total body stores of phosphorus during starvation and enhanced cellular uptake of phosp ...
... [DPG]) with inhibition of fat metabolism. This results in hypophosphatemia, the hallmark sign of RS. Additional mechanisms identified as contributing to low serum phosphorus concentrations include preexisting low total body stores of phosphorus during starvation and enhanced cellular uptake of phosp ...
Histopathology of bronchiectasis
... loss of cartilage [21]. There is usually a reduction in submucosal glands. The wall may be thin but is more often greatly thickened with extensive peribronchial fibrosis extending into the adjacent lung parenchyma (fig. 7) [22]. There is an associated chronic inflammatory cell infiltrate within the ...
... loss of cartilage [21]. There is usually a reduction in submucosal glands. The wall may be thin but is more often greatly thickened with extensive peribronchial fibrosis extending into the adjacent lung parenchyma (fig. 7) [22]. There is an associated chronic inflammatory cell infiltrate within the ...
CHAPTER I
... Viral respiratory tract infections are also a common occurrence in HIV-infected individuals. Immunological responses to viral infections depend on intact antibody responses, which are impaired in HIV-infected individuals. This is even more so in younger children who may have had no prior exposure to ...
... Viral respiratory tract infections are also a common occurrence in HIV-infected individuals. Immunological responses to viral infections depend on intact antibody responses, which are impaired in HIV-infected individuals. This is even more so in younger children who may have had no prior exposure to ...
Diagnosing the severity of dry eye
... developed to assess symptoms of dry eye.35–38 These tools are generally economically viable, correlate well with quality of life, have good sensitivity for DED diagnosis, and can be easily quantified. However, the panel also acknowledged that symptom assessments may not be easily reproducible, are no ...
... developed to assess symptoms of dry eye.35–38 These tools are generally economically viable, correlate well with quality of life, have good sensitivity for DED diagnosis, and can be easily quantified. However, the panel also acknowledged that symptom assessments may not be easily reproducible, are no ...
Is complement good, bad, or both? New functions of the complement
... chronic pain is significant. Complement activation in the peripheral nerve contributes to recruitment of immune cells and to neuropathic pain due to nerve injury. As complement activation following nerve injury has multiple consequences, further studies are needed to investigate the importance of th ...
... chronic pain is significant. Complement activation in the peripheral nerve contributes to recruitment of immune cells and to neuropathic pain due to nerve injury. As complement activation following nerve injury has multiple consequences, further studies are needed to investigate the importance of th ...
Two models of multiple sclerosis: Experimental allergic
... Theiler's murine encephalomyelitis virus (TMEV) infection and experimental allergic encephalomyelitis (EAE) are considered among the best models of human multiple sclerosis (MS). In both models, clinical disease is characterized by paralysis, while pathological changes consist of inflammatory demyel ...
... Theiler's murine encephalomyelitis virus (TMEV) infection and experimental allergic encephalomyelitis (EAE) are considered among the best models of human multiple sclerosis (MS). In both models, clinical disease is characterized by paralysis, while pathological changes consist of inflammatory demyel ...
bixbycenter.ucsf.edu
... plasma correlates with risk of disease in different at-risk populations – Number of CMV genomes (ie, viral load) present would indicate whether therapy is necessary because patients below a certain cut-off would not develop CMV disease – However, the level of viremia necessary for CMV disease to occ ...
... plasma correlates with risk of disease in different at-risk populations – Number of CMV genomes (ie, viral load) present would indicate whether therapy is necessary because patients below a certain cut-off would not develop CMV disease – However, the level of viremia necessary for CMV disease to occ ...
Immune System - Iowa State University Digital Repository
... pig are discussed in Chapter 56 of this book. Providing immunity at mucosal surfaces and to newborn piglets are especially difficult challenges for the immune system and for the swine producer. The nature of these special problems will be discussed as well as generalities about vaccination to improv ...
... pig are discussed in Chapter 56 of this book. Providing immunity at mucosal surfaces and to newborn piglets are especially difficult challenges for the immune system and for the swine producer. The nature of these special problems will be discussed as well as generalities about vaccination to improv ...
Author`s personal copy
... infection following a primary infection with dengue-1 virus.44 However, all serotypes have been shown to be capable of causing severe disease,45 and milder disease is associated with lower viral loads and high levels of preexisting heterotype neutralizing antibodies during the secondary infection. T ...
... infection following a primary infection with dengue-1 virus.44 However, all serotypes have been shown to be capable of causing severe disease,45 and milder disease is associated with lower viral loads and high levels of preexisting heterotype neutralizing antibodies during the secondary infection. T ...
Meibomian gland dysfunction
... that such a complicated gland structure gives rise to a lot of potential pathological insults, which is in fact the case in MGD,” explained Prof. Erich Knop who is the chair of the MGD Workshop Subcommittee for Anatomy, Physiology and Pathophysiology of the meibomian glands. Physiologically, it is n ...
... that such a complicated gland structure gives rise to a lot of potential pathological insults, which is in fact the case in MGD,” explained Prof. Erich Knop who is the chair of the MGD Workshop Subcommittee for Anatomy, Physiology and Pathophysiology of the meibomian glands. Physiologically, it is n ...
Simvastatin and Recombinant Antagonist of Receptors of Interleukin
... cytokines, resulting in a disturbed balance of proinflammatory versus anti-inflammatory cytokines. Although the increased levels of IL-1 and an imbalance between IL-1 and IL-1Ra have been documented, the role of other IL-1 modulators in IBD has not yet been elucidated. An imbalance between the produ ...
... cytokines, resulting in a disturbed balance of proinflammatory versus anti-inflammatory cytokines. Although the increased levels of IL-1 and an imbalance between IL-1 and IL-1Ra have been documented, the role of other IL-1 modulators in IBD has not yet been elucidated. An imbalance between the produ ...
C. Lymphocyte - El Camino College
... 2. Caused by Epstein-Barr _______, which attacks B lymphocytes, causing massive activation of T lymphocytes that attack the B cells. 3. Symptoms include fatigue, fever, sore throat, & swollen lymph ________; lasts about 4-6 weeks. 4. Virus remains in the body and can cause _________________ Syndrome ...
... 2. Caused by Epstein-Barr _______, which attacks B lymphocytes, causing massive activation of T lymphocytes that attack the B cells. 3. Symptoms include fatigue, fever, sore throat, & swollen lymph ________; lasts about 4-6 weeks. 4. Virus remains in the body and can cause _________________ Syndrome ...
Autoimmune Hemolytic Anemia and Red Blood Cell Autoantibodies
... amplitude can fix complement when patients are exposed to cold temperatures, such as those occurring during winter months at northern latitudes, or when patients undergo cooling during a cardiopulmonary bypass procedure. This phenomena most often occurs in a patient’s extremities, resulting in hemol ...
... amplitude can fix complement when patients are exposed to cold temperatures, such as those occurring during winter months at northern latitudes, or when patients undergo cooling during a cardiopulmonary bypass procedure. This phenomena most often occurs in a patient’s extremities, resulting in hemol ...
In Vivo CD40-gp39 Interactions Are Essential for Thymus
... B lymphocytes from these patients are reported to be normal (18, 19, 21), mutations in the gp39 molecule interrupt B cell triggering through CD40 and subsequent B cell activation and Ig production. The present study examines the ability of a mAb specific for gp39 to neutralize the function of gp39 i ...
... B lymphocytes from these patients are reported to be normal (18, 19, 21), mutations in the gp39 molecule interrupt B cell triggering through CD40 and subsequent B cell activation and Ig production. The present study examines the ability of a mAb specific for gp39 to neutralize the function of gp39 i ...
Signs And Symptoms of Heart Failure
... This descriptive, cross-sectional study was conducted at the Cleveland Clinic in Cleveland, Ohio, a large tertiary care medical center with both ambulatory care and hospital services, including cardiac transplantation, for patients with heart failure. The institutional review board approved the stud ...
... This descriptive, cross-sectional study was conducted at the Cleveland Clinic in Cleveland, Ohio, a large tertiary care medical center with both ambulatory care and hospital services, including cardiac transplantation, for patients with heart failure. The institutional review board approved the stud ...
Juvenile Idiopathic Arthritis associated uveitis C. Michael Samson
... Posterior synechiae, cataract, and band keratopathy are some of the more common findings. [7,12] These findings are not specific for JIA, and may be present in children with uveitis due to other etiologies. Glaucoma is also commonly seen in this form of uveitis. [12] Acute or chronic angle-closure g ...
... Posterior synechiae, cataract, and band keratopathy are some of the more common findings. [7,12] These findings are not specific for JIA, and may be present in children with uveitis due to other etiologies. Glaucoma is also commonly seen in this form of uveitis. [12] Acute or chronic angle-closure g ...
Preliminary evaluation of tear production in dogs hospitalized in an
... abnormalities (eg, anemia, thrombotic disease), and each of the following disorders were represented once: extrahepatic portosystemic shunt, trauma (hit by car) and hypertrophic osteodystrophy. Patient records were examined and previous medical therapy was available for 25/30 animals. Of these 25 pa ...
... abnormalities (eg, anemia, thrombotic disease), and each of the following disorders were represented once: extrahepatic portosystemic shunt, trauma (hit by car) and hypertrophic osteodystrophy. Patient records were examined and previous medical therapy was available for 25/30 animals. Of these 25 pa ...
Alterations of cell-mediated immunity following cardiac operations
... Cytokine measurements provide more detailed information: IL-2 and IL-12, which are important for the activation of the type-1 TH-cell (TH1)-mediated immune response, are depressed following cardiac operation. In contrast, IL-10 and transforming growth factor-ß essential to TH2-mediated humoral or an ...
... Cytokine measurements provide more detailed information: IL-2 and IL-12, which are important for the activation of the type-1 TH-cell (TH1)-mediated immune response, are depressed following cardiac operation. In contrast, IL-10 and transforming growth factor-ß essential to TH2-mediated humoral or an ...
Bee Propolis: Ancient Cure for Today`s Ailments
... James, J.S. (1987, July 31). Bee Propolis for Thrush, Fungus or Leukoplakia? AIDS Treatment News, 1(37), Retrieved September 19, 2005, from the World Wide Web: http://www.aids.org/atn/a-037-01.html Kulinčevića, J. & Gačića, R. (1991). Propolis. Retrieved November 14, 2005, from the World Wide Web: h ...
... James, J.S. (1987, July 31). Bee Propolis for Thrush, Fungus or Leukoplakia? AIDS Treatment News, 1(37), Retrieved September 19, 2005, from the World Wide Web: http://www.aids.org/atn/a-037-01.html Kulinčevića, J. & Gačića, R. (1991). Propolis. Retrieved November 14, 2005, from the World Wide Web: h ...
Management of early rheumatoid arthritis. (SIGN Guideline No 123)
... Methotrexate and sulfasalazine are the DMARDs of choice due to their more favourable efficacy and toxicity profiles. B DMARD therapy should be sustained in patients with early RA to control the signs and symptoms of disease. A A combination DMARD strategy, rather than sequential monotherapy, ...
... Methotrexate and sulfasalazine are the DMARDs of choice due to their more favourable efficacy and toxicity profiles. B DMARD therapy should be sustained in patients with early RA to control the signs and symptoms of disease. A A combination DMARD strategy, rather than sequential monotherapy, ...