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Different Types of Vaccine Whole virus vaccines. either live or killed
Different Types of Vaccine Whole virus vaccines. either live or killed

... sequences. The resultant recombination vector is then introduced into cells infected with vaccinia virus to generate a virus that expresses the foreign gene. The recombinant virus vaccine can then multiply in infected cells and produce the antigens of a wide range of viruses. The genes of several vi ...
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De novo design and Synthesis of a Cationic Antimicrobial peptide

PPT Version - OMICS International
PPT Version - OMICS International

... • Due to the level of detail at which individual components are represented, ABMs can be computationally expensive and sometimes intractable. Population level approaches like ordinary differential equations (ODEs) are computationally tractable and can scale up to simulate host pathogen dynamics in l ...
Question 1
Question 1

... bacterial membrane. Macrophages kill bacterial microbes by ingesting and lysing. or Complement kills bacterial microbes by punching holes in the bacterial membrane. e) A single B cell can produce many different kinds of surface antibody molecules. A single B cell can produce only one kind of surface ...
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BIOT 307: MOLECULAR IMMUNOLOGY
BIOT 307: MOLECULAR IMMUNOLOGY

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Special virology 1. Rotavirus 2. Enterovirus polio
Special virology 1. Rotavirus 2. Enterovirus polio

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Immune defence in the lymphatic system of the skin

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Kuby Immunology 6/e - Dr. Jennifer Capers, PhD

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The Role of Protein in Dairy Cattle Nutrition
The Role of Protein in Dairy Cattle Nutrition

... microbial protein. The blend of amino acids available to the cow is a combination of those released by intestinal digestion of both microbial and undegraded feed proteins. The total amount of protein available to the animal for metabolism is referred to as Metabolizable Protein. When the blend of am ...
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Molecular mimicry

Molecular mimicry is defined as the theoretical possibility that sequence similarities between foreign and self-peptides are sufficient to result in the cross-activation of autoreactive T or B cells by pathogen-derived peptides. Despite the promiscuity of several peptide sequences which can be both foreign and self in nature, a single antibody or TCR (T cell receptor) can be activated by even a few crucial residues which stresses the importance of structural homology in the theory of molecular mimicry. Upon the activation of B or T cells, it is believed that these ""peptide mimic"" specific T or B cells can cross-react with self-epitopes, thus leading to tissue pathology (autoimmunity). Molecular mimicry is a phenomenon that has been just recently discovered as one of several ways in which autoimmunity can be evoked. A molecular mimicking event is, however, more than an epiphenomenon despite its low statistical probability of occurring and these events have serious implications in the onset of many human autoimmune disorders. In the past decade the study of autoimmunity, the failure to recognize self antigens as ""self,"" has grown immensely. Autoimmunity is a result of a loss of immunological tolerance, the ability for an individual to discriminate between self and non-self. Growth in the field of autoimmunity has resulted in more and more frequent diagnosis of autoimmune diseases. Consequently, recent data show that autoimmune diseases affect approximately 1 in 31 people within the general population. Growth has also led to a greater characterization of what autoimmunity is and how it can be studied and treated. With an increased amount of research, there has been tremendous growth in the study of the several different ways in which autoimmunity can occur, one of which is molecular mimicry. The mechanism by which pathogens have evolved, or obtained by chance, similar amino acid sequences or the homologous three-dimensional crystal structure of immunodominant epitopes remains a mystery.
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