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WHO clinical staging of HIV disease in adults and adolescents (2/4)
WHO clinical staging of HIV disease in adults and adolescents (2/4)

... Effect of HIV on the Immune System • Reduction in the CD4 cell number and the effects on their function reduces the capacity of the body to fight infectious diseases. • Individuals with HIV infection are therefore increasingly susceptible to many infections especially at later stages of HIV infecti ...
Lymphatic System Notes (2 of 3)
Lymphatic System Notes (2 of 3)

... 3. Helper T Cells (type of T cell) to trigger Cytotoxic T Cells to release their chemicals to attack intracellular Ag’s (ex. cancer, viral infected cells & transplanted tissue): ...
Establishment and characterization of a retinal Müller cell line.
Establishment and characterization of a retinal Müller cell line.

... efficiency. All values are expressed as mean ± SEM for three separate determinations. ...
Zánět
Zánět

... • The innate system reacts promptly without specificity and memory. Phagocytic cells are important contributors in innate reactivity together with enzymes, complement activation and acute phase proteins. When phagocytic cells are activated, the synthesis of different cytokines is triggered. These cy ...
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry

... glycomics, the systematic characterization of all of the carbohydrate components of a given cell or tissue, offers insight into the normal patterns of glycosylation in cells and how they may be perturbed in diseases such as cancer. ...
Blood Type - Wilson`s Web Page
Blood Type - Wilson`s Web Page

... • Due to antigens on the surface of RBC’s • If the same antigen and antibody are present, agglutination (clumping) of RBCs will occur, causing death • Blood recipients may only receive donated blood for which they have no antibodies in their plasma. ...
Pathogens – Bacteria & Viruses
Pathogens – Bacteria & Viruses

...  Genetic material is DNA or RNA  Coat is protein head ...
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Toxins produced by gram positive bacteria(2)

... Enterotoxins are superantigens that are even more heatstable than S. aureus; therefore, organisms are not always recovered from incriminated food. They polymerize into tubes that pierce membranes, resulting in the loss of important molecules and, eventually, in osmotic lysis . They stimulate the vom ...
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Reasons why there is a high incidence of septic shock

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B.Sc. Microbiology Part-II-2013

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The Immune System and Immunisation

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葉才明

... • Most vaccines are still given by injection. • Vaccine efficacy needs to be reviewed from time to time. • Vaccine safety is an overriding consideration. • Vaccines in general use have variable success rates. • Passive immunization can be life-saving. • Non-specific immunotherapy can boost immune ac ...
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Pathophysiology of Type 1 Diabetes

... CD8, cluster of differentiation 8; FasL, Fas ligand; IFN-g, interferon g; IL-1, interleukin 1; MHC, major histocompatibility complex; NO, nitric oxide; TNF-a, tumor necrosis factor a. Maahs DM, et al. Endocrinol Metab Clin North Am. 2010;39:481-497. ...
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... • Antibodies are proteins created by B cells that bind to pathogens, a key step in our immune response. • We are able to create a large variety of antibodies using VDJ Recombination and turning genes on and off. • B cells mount an immune response by undergoing clonal expansion. • We are protected fr ...
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... CD8, cluster of differentiation 8; FasL, Fas ligand; IFN-g, interferon g; IL-1, interleukin 1; MHC, major histocompatibility complex; NO, nitric oxide; TNF-a, tumor necrosis factor a. Maahs DM, et al. Endocrinol Metab Clin North Am. 2010;39:481-497. ...
BioSc221/325 Exam 1 Name
BioSc221/325 Exam 1 Name

... Microbes such as Deinococcus radiodurams that are able to survive high levels of radiation exposure probably possess what type of protective mechanism? Because radiation kills cells by damaging DNA radiation resistant bacteria have very active DNA repair systems. List two characteristics of endospor ...
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Chapter 13 Practice Q`s - Website of Neelay Gandhi

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PHA 321 - Biosciences II

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Very Diverse CD8 T Cell Clonotypic Responses after Virus
Very Diverse CD8 T Cell Clonotypic Responses after Virus

Use of Undenatured Type II Collagen in the Treatment - Flex
Use of Undenatured Type II Collagen in the Treatment - Flex

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Molecular mimicry

Molecular mimicry is defined as the theoretical possibility that sequence similarities between foreign and self-peptides are sufficient to result in the cross-activation of autoreactive T or B cells by pathogen-derived peptides. Despite the promiscuity of several peptide sequences which can be both foreign and self in nature, a single antibody or TCR (T cell receptor) can be activated by even a few crucial residues which stresses the importance of structural homology in the theory of molecular mimicry. Upon the activation of B or T cells, it is believed that these ""peptide mimic"" specific T or B cells can cross-react with self-epitopes, thus leading to tissue pathology (autoimmunity). Molecular mimicry is a phenomenon that has been just recently discovered as one of several ways in which autoimmunity can be evoked. A molecular mimicking event is, however, more than an epiphenomenon despite its low statistical probability of occurring and these events have serious implications in the onset of many human autoimmune disorders. In the past decade the study of autoimmunity, the failure to recognize self antigens as ""self,"" has grown immensely. Autoimmunity is a result of a loss of immunological tolerance, the ability for an individual to discriminate between self and non-self. Growth in the field of autoimmunity has resulted in more and more frequent diagnosis of autoimmune diseases. Consequently, recent data show that autoimmune diseases affect approximately 1 in 31 people within the general population. Growth has also led to a greater characterization of what autoimmunity is and how it can be studied and treated. With an increased amount of research, there has been tremendous growth in the study of the several different ways in which autoimmunity can occur, one of which is molecular mimicry. The mechanism by which pathogens have evolved, or obtained by chance, similar amino acid sequences or the homologous three-dimensional crystal structure of immunodominant epitopes remains a mystery.
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