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Monoclonal antibodies to equine arteritis virus proteins identify the
Monoclonal antibodies to equine arteritis virus proteins identify the

1. Inflammation
1. Inflammation

Free fucose is a danger signal to human intestinal epithelial cells
Free fucose is a danger signal to human intestinal epithelial cells

microbiology ch 42 [9-4
microbiology ch 42 [9-4

...  Clinical symptoms associated w/CMV and EBV self-limited, little value in antiviral therapy (host immune system already reacting when symptoms show)  Atypical lymphocytes seen in infectious mono are activated CD8+ T lymphocytes directed against viral antigens on infected cells; critical to control ...
Sat. APRIL 25TH | uc berkeley
Sat. APRIL 25TH | uc berkeley

... light, demonstrating that ppGpp is important for fitness under oscillating environmental conditions. Using RNA-seq to compare gene expression levels among strains with varying ppGpp levels in light and dark, we have identified many ppGpp-regulated genes. We are following up on several of these targe ...
MaX VRL - Xymogen
MaX VRL - Xymogen

Analysis of a wild mouse promoter variant reveals a novel role
Analysis of a wild mouse promoter variant reveals a novel role

... Genetic variants of the inhibitory Fc receptor FcRIIb have been associated with systemic lupus erythematosus in humans and mice. The mechanism by which Fcgr2b variants contribute to the development of autoimmunity is unknown and was investigated by knocking in the most commonly conserved wild mouse ...
SYLLABUS FOR M.Sc. SEMESTER PATTERN
SYLLABUS FOR M.Sc. SEMESTER PATTERN

... oncogenes and cancer induction, Tumor Antigens, Immune surveillance theory, Tumor evasion of the Immune system, Cancer Immunotherapy. Transplantation Immunology: Immunological basis of Graft Rejection, Mechanism of Graft rejection. Immunosuppressive therapy: General and specific. Clinical Transplant ...
Adaptive Immunity from Prokaryotes to Eukaryotes
Adaptive Immunity from Prokaryotes to Eukaryotes

... cancer. Briefly the immune system consists of: Innate: natural, nonspecific, no memory, nonanticipatory, non-clonal, germ line; Adaptive: acquired, specific, memory, anticipatory, clonal, somatic. In general, both systems and in the simplest reductionist terms, each must possess a cell that recogniz ...
Unit 6 Exam Review
Unit 6 Exam Review

... 1. Which leukocytes increases in numbers with a bacterial infection? 2. Which leukocytes do not directly attack pathogens, but instead release cytokines to attract other leukocytes? 3. Which leukocytes wander through tissues destroying bacteria, and are part of immune surveillance? 4. Which leukocyt ...
A c a d
A c a d

... cytokines such as interleukins-6 (IL-6), interleukin 1β (IL-1β), tumour necrosis factor-alfa (TNF- α) and acute phase proteins. Typical symptoms are sudden inflammation in the affected area and mild stiffness in joints. The symptoms can lead in others to deformations in the feet and hands as a resul ...
PDF + SI - The Journal of Immunology
PDF + SI - The Journal of Immunology

... upstart field of virology. It had just been realized that viruses were different from bacteria in that they replicated through a means beyond binary fission within animal cells. This replication occurred during what the early virologist Leslie Hoyle described as the eclipse phase in his studies of I ...
Figure 1 - Open Biology
Figure 1 - Open Biology

Dendritic cells
Dendritic cells

As listed in the 2016 Physicians` Desk Reference (PDR)
As listed in the 2016 Physicians` Desk Reference (PDR)

... 1. It  is  the  major  endogenous  antioxidant  produced  by  the  cells,  participating  directly  in  the  neutralization  of  free  radicals  and  reactive  oxygen  compounds,  as  well  as  maintaining  exogenous antioxidants such as vitamins C and E in their reduced (active) forms.  2. Through  ...
The Plague
The Plague

May 2006 - InvivoGen
May 2006 - InvivoGen

... Therapeutic antibody architecture and structural features ...
Impact of IgA Constant Domain on HIV
Impact of IgA Constant Domain on HIV

Autoimmune/inflammatory syndrome induced by adjuvants (ASIA
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA

The NLRP12 Sensor Negatively Regulates Autoinflammatory
The NLRP12 Sensor Negatively Regulates Autoinflammatory

... signaling, and multiple NLRs have been identified as critically involved in the regulation of proinflammatory cytokine production by antigen-presenting cells. In contrast, the ability of NLRs to modulate T cell responses and how NLR-dependent control of T cells influences autoinflammatory disease pr ...
PPT - IAS-USA
PPT - IAS-USA

... proliferation ...
BiPRO - SupplySide Database
BiPRO - SupplySide Database

... isolate with an excellent amino acid profile, containing all of the essential and nonessential amino acids, which can improve the overall protein quality of an infant formula and lower the total protein content. BiPRO can be used to replace demineralized whey in regular infant formula on a protein b ...
Regulatory T Cells and Viral Disease
Regulatory T Cells and Viral Disease

... regulatory T cells. Recent studies have shown that multiple CD4+ T cells are actually generated in vivo, rather than distinct subsets as previously thought. The effector cells secrete large amounts of cytokines, chemokines, and other proteins that can produce cytotoxicity to host tissues, or induce ...
Helper T cells and atherosclerosis: the cytokine web
Helper T cells and atherosclerosis: the cytokine web

Abbreviations - Danish Medical Bulletin
Abbreviations - Danish Medical Bulletin

... Reingold 1996]. After 10-15 years, RRMS often develops into a secondary progressive form (SPMS), characterised by progressive loss of neurological functions, that resembles PPMS, with or without superimposed relapses [Confavreux and Vukusic 2006]. RRMS is characterised by episodes of acute relapses ...
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Molecular mimicry

Molecular mimicry is defined as the theoretical possibility that sequence similarities between foreign and self-peptides are sufficient to result in the cross-activation of autoreactive T or B cells by pathogen-derived peptides. Despite the promiscuity of several peptide sequences which can be both foreign and self in nature, a single antibody or TCR (T cell receptor) can be activated by even a few crucial residues which stresses the importance of structural homology in the theory of molecular mimicry. Upon the activation of B or T cells, it is believed that these ""peptide mimic"" specific T or B cells can cross-react with self-epitopes, thus leading to tissue pathology (autoimmunity). Molecular mimicry is a phenomenon that has been just recently discovered as one of several ways in which autoimmunity can be evoked. A molecular mimicking event is, however, more than an epiphenomenon despite its low statistical probability of occurring and these events have serious implications in the onset of many human autoimmune disorders. In the past decade the study of autoimmunity, the failure to recognize self antigens as ""self,"" has grown immensely. Autoimmunity is a result of a loss of immunological tolerance, the ability for an individual to discriminate between self and non-self. Growth in the field of autoimmunity has resulted in more and more frequent diagnosis of autoimmune diseases. Consequently, recent data show that autoimmune diseases affect approximately 1 in 31 people within the general population. Growth has also led to a greater characterization of what autoimmunity is and how it can be studied and treated. With an increased amount of research, there has been tremendous growth in the study of the several different ways in which autoimmunity can occur, one of which is molecular mimicry. The mechanism by which pathogens have evolved, or obtained by chance, similar amino acid sequences or the homologous three-dimensional crystal structure of immunodominant epitopes remains a mystery.
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