Intro, show Jurassic Park, relate to all other units, Discuss history
... Intro, show Jurassic Park, relate to all other units, Discuss history DNA in each cell weighs 6 millionth of a gram. All the people’s DNA (5.8 billion) total weight would be 1/30th of a gram The total length of DNA is thousands of times larger than the nucleus. (2.2 m) It has to be condensed so that ...
... Intro, show Jurassic Park, relate to all other units, Discuss history DNA in each cell weighs 6 millionth of a gram. All the people’s DNA (5.8 billion) total weight would be 1/30th of a gram The total length of DNA is thousands of times larger than the nucleus. (2.2 m) It has to be condensed so that ...
procedure - DNA Interactive
... recombinant DNA methods and the discovery of transposable elements in everything from bacteria to humans, to give her ideas wide acceptance. In 1983, three decades after her work was first published, she was awarded the Nobel Prize for her work. Currently, transposable elements are one of the most p ...
... recombinant DNA methods and the discovery of transposable elements in everything from bacteria to humans, to give her ideas wide acceptance. In 1983, three decades after her work was first published, she was awarded the Nobel Prize for her work. Currently, transposable elements are one of the most p ...
Cross over frequency and gene mapping Notes
... Crossing over – homologous chromosomes pair up during prophase I, they may exchange pieces of chromosome Linked genes do not always stay together in gamete formation Crossing over results in new combinations of genes Crossing over occurs during meiosis and cause linked genes to separate. ...
... Crossing over – homologous chromosomes pair up during prophase I, they may exchange pieces of chromosome Linked genes do not always stay together in gamete formation Crossing over results in new combinations of genes Crossing over occurs during meiosis and cause linked genes to separate. ...
Yeast as a navigational aid in genome analysis
... profile together with its calculated pmaxunder the same conditions (equivalent to the rate of flux when determined under steady-state conditions) provide two essential pieces of information that should allow the site of action of a novel gene product to be located on the yeast metabolic map. If, by ...
... profile together with its calculated pmaxunder the same conditions (equivalent to the rate of flux when determined under steady-state conditions) provide two essential pieces of information that should allow the site of action of a novel gene product to be located on the yeast metabolic map. If, by ...
Microbial Genetics Thesaurus
... SN A selective increase in the number of copies of a gene coding for a specific protein without a proportional increase in other genes. It occurs naturally via the excision of a copy of the repeating sequence from the chromosome and its extrachromosomal replication in a plasmid, or via the productio ...
... SN A selective increase in the number of copies of a gene coding for a specific protein without a proportional increase in other genes. It occurs naturally via the excision of a copy of the repeating sequence from the chromosome and its extrachromosomal replication in a plasmid, or via the productio ...
How to determine whether a gene is essential for survival. Background
... ectopic integration following transformation. Two ways have been described for obtaining heterokaryotic single-ascospore progeny. 'Sheltered disruption' (Metzenberg and Groteluechen 1992) and 'Rip & Rescue' (Ferea and Bowman 1996). Sheltered disruption uses as one parent a strain that generates diso ...
... ectopic integration following transformation. Two ways have been described for obtaining heterokaryotic single-ascospore progeny. 'Sheltered disruption' (Metzenberg and Groteluechen 1992) and 'Rip & Rescue' (Ferea and Bowman 1996). Sheltered disruption uses as one parent a strain that generates diso ...
chapter 1 - VU-DARE
... species and within species and thus to analyze variation in a genome-wide manner. It also has become possible to analyze genomes from less-investigated invertebrate species that are not considered to be classical genetic models. This has given rise to new insights into the tree of life, into the nat ...
... species and within species and thus to analyze variation in a genome-wide manner. It also has become possible to analyze genomes from less-investigated invertebrate species that are not considered to be classical genetic models. This has given rise to new insights into the tree of life, into the nat ...
2004-06-GO_labday_aireland
... a set of functions eg. signal transduction, behavior, glycolysis, regulation of cell size GO terms are made up of a term name, a unique ID, and (for 90% of terms) a definition. GO terms may also have synonyms, which can be either identical or related concepts; the relationship between the term and s ...
... a set of functions eg. signal transduction, behavior, glycolysis, regulation of cell size GO terms are made up of a term name, a unique ID, and (for 90% of terms) a definition. GO terms may also have synonyms, which can be either identical or related concepts; the relationship between the term and s ...
Is there a link between DNA and Obesity?
... Every gene is interrupted by a DNA strand known as an intron. Researchers discovered a “genetic switch” with in the FTO gene’s intron. If a human has the high obesity-risk variant gene, it affects the introns. The introns, when affected by this FTO gene variant, doubles the activity of two other gen ...
... Every gene is interrupted by a DNA strand known as an intron. Researchers discovered a “genetic switch” with in the FTO gene’s intron. If a human has the high obesity-risk variant gene, it affects the introns. The introns, when affected by this FTO gene variant, doubles the activity of two other gen ...
Structural and Functional Genomics of Tomato
... – economically important crop worldwide, – intensively investigated and – model system for genetic studies in plants. ...
... – economically important crop worldwide, – intensively investigated and – model system for genetic studies in plants. ...
Genome-wide RNAi screening in Caenorhabditis elegans
... •1984: Stout & Caskey show antisense RNA can be used to silence gene expression in Mammalian tissue cultures •1990: Fire & Moerman show antisense RNA can disrupt myofilament protein encoding genes •1995: Guo & Kemphues accidentally discover that sense RNA can is as effective as antisense RNA in gene ...
... •1984: Stout & Caskey show antisense RNA can be used to silence gene expression in Mammalian tissue cultures •1990: Fire & Moerman show antisense RNA can disrupt myofilament protein encoding genes •1995: Guo & Kemphues accidentally discover that sense RNA can is as effective as antisense RNA in gene ...
Gene exspression
... on glass slides at very high density. • Fragments at each specific location are usually designed as complementary to part of the mRNA (or its cDNA) of a certain gene. • The use of the DNA chips is based on hybridization between the fragments attached to the glass and the mRNA (or its cDNA) from the ...
... on glass slides at very high density. • Fragments at each specific location are usually designed as complementary to part of the mRNA (or its cDNA) of a certain gene. • The use of the DNA chips is based on hybridization between the fragments attached to the glass and the mRNA (or its cDNA) from the ...
Structure, Expression and Duplication of Genes Which Encode
... isolated. All contained anidentically sized insert of 1 kb. The clones were sequenced and found to contain a PGLYM encoding open reading frame by comparison to the human PGLYM amino acid sequence. ADrosophila cDNA clone was used to probe a Southernblot of Drosophila genomic DNA. This analysis (Figur ...
... isolated. All contained anidentically sized insert of 1 kb. The clones were sequenced and found to contain a PGLYM encoding open reading frame by comparison to the human PGLYM amino acid sequence. ADrosophila cDNA clone was used to probe a Southernblot of Drosophila genomic DNA. This analysis (Figur ...
Integrons: natural tools for bacterial genome evolution
... There is evidence that not all repeated sequences are equally functional. Some are known to contain mutations or deletions within the CS that could render them nonfunctional (DA Rowe-Magnus, A-M Guerout, D Mazel, unpublished data). Therefore, their movement would have to be co-ordinated with those o ...
... There is evidence that not all repeated sequences are equally functional. Some are known to contain mutations or deletions within the CS that could render them nonfunctional (DA Rowe-Magnus, A-M Guerout, D Mazel, unpublished data). Therefore, their movement would have to be co-ordinated with those o ...
Dot plot - TeachLine
... Compare new genes to known ones Compare genes from different species information about evolution ...
... Compare new genes to known ones Compare genes from different species information about evolution ...
Genome browsers and other resources
... eukaryotic genomes that best reflect complex allelic diversity consistent with currently available data. Currently produces assemblies for human, mouse and ...
... eukaryotic genomes that best reflect complex allelic diversity consistent with currently available data. Currently produces assemblies for human, mouse and ...
Build a bug activity Salmonella
... to adhere to and colonise the gut of host organisms Genes which no longer function or have been inactivated; implicated in the ability of Salmonella to cause Typhoid fever. Clusters of genes unique to the Salmonella Typhi bacterial chromosome. Clusters of genes linked with causing diarrhoea in human ...
... to adhere to and colonise the gut of host organisms Genes which no longer function or have been inactivated; implicated in the ability of Salmonella to cause Typhoid fever. Clusters of genes unique to the Salmonella Typhi bacterial chromosome. Clusters of genes linked with causing diarrhoea in human ...
EAWAG news 56e: Genomic Islands and Horizontal Gene Transfer
... happening to the chromosomal DNA. Or is it? Bacterial chromosomes are now known to harbor what is called “genomic islands”, regions which can cut themselves out of the chromosome, in some cases travel to other bacterial cells and reinsert into the recipient’s chromosome. Their function? Very often, ...
... happening to the chromosomal DNA. Or is it? Bacterial chromosomes are now known to harbor what is called “genomic islands”, regions which can cut themselves out of the chromosome, in some cases travel to other bacterial cells and reinsert into the recipient’s chromosome. Their function? Very often, ...
presentation UCSC part 1 - Biomedical Genomics Group
... …are all saved on your computer. When you come back in a couple of days to use it again, these will still be set. You may— or may not—intend this. ...
... …are all saved on your computer. When you come back in a couple of days to use it again, these will still be set. You may— or may not—intend this. ...
Annotation
... tRNA Scan. Like its name implies, it is used to detect putative tRNA producing sequences. Instead of making proteins, these are copied into tRNA molecules. This program will identify whether your genome has any tRNAs and give you output (printouts) of what each one looks like. 8. We’ll search for an ...
... tRNA Scan. Like its name implies, it is used to detect putative tRNA producing sequences. Instead of making proteins, these are copied into tRNA molecules. This program will identify whether your genome has any tRNAs and give you output (printouts) of what each one looks like. 8. We’ll search for an ...
The Discovery of Transposition
... It was at about this time that McClintock became aware that Ds could move. In her Carnegie Yearbook report for 1947-48 (1474), the simple statement appears: "It is now known that the Ds locus may change its position in the chromosome after such coincidental [chromosome] breaks have occurred." This s ...
... It was at about this time that McClintock became aware that Ds could move. In her Carnegie Yearbook report for 1947-48 (1474), the simple statement appears: "It is now known that the Ds locus may change its position in the chromosome after such coincidental [chromosome] breaks have occurred." This s ...
presentation (spanish ppt format, 4.7 MB)
... scientists in the United States and the Netherlands in the early 1990s. In an attempt to alter flower colors in petunias, researchers introduced additional copies of a gene encoding chalcone synthase, a key enzyme for flower pigmentation into petunia plants of normally pink or violet flower color. T ...
... scientists in the United States and the Netherlands in the early 1990s. In an attempt to alter flower colors in petunias, researchers introduced additional copies of a gene encoding chalcone synthase, a key enzyme for flower pigmentation into petunia plants of normally pink or violet flower color. T ...
Document
... years ago, that is roughly 6 mutations per year that get fixed within the genome (or 3 per year if you divide them equally amongst the 2 branching species). Given a conservative estimate of average generational time of 10 years, this means that 30 new mutations had to be fixed within the population ...
... years ago, that is roughly 6 mutations per year that get fixed within the genome (or 3 per year if you divide them equally amongst the 2 branching species). Given a conservative estimate of average generational time of 10 years, this means that 30 new mutations had to be fixed within the population ...
complex polypeptide-1 gene and related sequences
... and a wild-type chromosome 17. When such males (t x /+) are mated with wildtype females, up to 99 % of the eggs are fertilized by the sperm bearing the f-chromosome. The t x /+ males produce roughly equal quantities of tx and wildtype sperm as shown by probing their sperm DNA with polymorphic microc ...
... and a wild-type chromosome 17. When such males (t x /+) are mated with wildtype females, up to 99 % of the eggs are fertilized by the sperm bearing the f-chromosome. The t x /+ males produce roughly equal quantities of tx and wildtype sperm as shown by probing their sperm DNA with polymorphic microc ...
Microbes R the Biosphere?
... B) Mutations occur at a higher rate in non-coding sequences than in protein-coding sequences. C) Mutations in exons are more likely to be corrected by DNA repair enzymes than mutations in introns or intergenic regions. D) Mutations arise and persist in the human population at equal rates in non-codi ...
... B) Mutations occur at a higher rate in non-coding sequences than in protein-coding sequences. C) Mutations in exons are more likely to be corrected by DNA repair enzymes than mutations in introns or intergenic regions. D) Mutations arise and persist in the human population at equal rates in non-codi ...
Transposable element
A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.