Evolution
... the Human Genome Project were able to identify and map the 20,000–25,000 genes that define a human being. The project also successfully mapped the genomes of other species, including the fruit fly, mouse, and Escherichia coli. The location and complete sequence of the genes in each of these species ...
... the Human Genome Project were able to identify and map the 20,000–25,000 genes that define a human being. The project also successfully mapped the genomes of other species, including the fruit fly, mouse, and Escherichia coli. The location and complete sequence of the genes in each of these species ...
The Complete Sequence of 340 kb of DNA around the
... A 2.3-centimorgan (cM) segment of rice chromosome 11 consisting of 340 kb of DNA sequence around the alcohol dehydrogenase Adh1 and Adh2 loci was completely sequenced, revealing the presence of 33 putative genes, including several apparently involved in disease resistance. Fourteen of the genes were ...
... A 2.3-centimorgan (cM) segment of rice chromosome 11 consisting of 340 kb of DNA sequence around the alcohol dehydrogenase Adh1 and Adh2 loci was completely sequenced, revealing the presence of 33 putative genes, including several apparently involved in disease resistance. Fourteen of the genes were ...
Ensembl gene annotation project (e!74
... and the remaining unique set of transcript models were clustered into multi-transcript genes where each transcript in a gene has at least one coding exon that overlaps a coding exon from another transcript within the same gene. At this stage the gene set comprised of 23074 genes with 23730 transcrip ...
... and the remaining unique set of transcript models were clustered into multi-transcript genes where each transcript in a gene has at least one coding exon that overlaps a coding exon from another transcript within the same gene. At this stage the gene set comprised of 23074 genes with 23730 transcrip ...
Exercise 2 — Zebrafish
... (a) How many orthologues are predicted for this gene in primates? How much sequence identity does the Tarsius syrichta protein have to the human one? Click on the Alignment link next to the Ensembl identifier column to view a protein alignment in ...
... (a) How many orthologues are predicted for this gene in primates? How much sequence identity does the Tarsius syrichta protein have to the human one? Click on the Alignment link next to the Ensembl identifier column to view a protein alignment in ...
Comparison of two known chromosomal rearrangements in the
... unexpectedly low level of HbA2 observed in both cases. The high HbF level in case 3 on the other hand can be explained by the additional thalassemic -29A>G mutation, leading to thalintermedia. The chromosomal rearrangements described here are very likely the result of unequal crossover between misal ...
... unexpectedly low level of HbA2 observed in both cases. The high HbF level in case 3 on the other hand can be explained by the additional thalassemic -29A>G mutation, leading to thalintermedia. The chromosomal rearrangements described here are very likely the result of unequal crossover between misal ...
BMC Research Notes - FABI
... arrangements among them [11,12]. Such information can either be derived from phylogenetic profiles [13] or from comparative genome analyses [14]. The information may also provide insight into these organisms' evolutionary history and metabolic capabilities [15]. ...
... arrangements among them [11,12]. Such information can either be derived from phylogenetic profiles [13] or from comparative genome analyses [14]. The information may also provide insight into these organisms' evolutionary history and metabolic capabilities [15]. ...
Physiology is rocking the foundations of evolutionary biology
... of ‘natural’ genetic engineering, while table II.11 from the same book (pp. 84–86; http://shapiro.bsd.uchicago. edu/TableII.11.shtml) documents the regions of the genomes targeted. Thirty-two examples are given. One example will suffice to illustrate this. P element homing in fruit flies involves DN ...
... of ‘natural’ genetic engineering, while table II.11 from the same book (pp. 84–86; http://shapiro.bsd.uchicago. edu/TableII.11.shtml) documents the regions of the genomes targeted. Thirty-two examples are given. One example will suffice to illustrate this. P element homing in fruit flies involves DN ...
IJBT 10(3) 270-273
... cloned from E. fetida and L. rubellus with 63% bootstrap value. This analysis of Efp-0 gene showed that individuals belonging to E. eugeniae can be distinguished from other species based on the sequences of single gene. Earthworm fibrinolytic enzymes are a group of serine proteases, which have stron ...
... cloned from E. fetida and L. rubellus with 63% bootstrap value. This analysis of Efp-0 gene showed that individuals belonging to E. eugeniae can be distinguished from other species based on the sequences of single gene. Earthworm fibrinolytic enzymes are a group of serine proteases, which have stron ...
Transcription and RNA processing
... prokaryotic and eukaryotic genes, transcription begins at a DNA sequence that is upstream (to the “left” on the DNA) of the first codon (i.e., at the promoter), and ends downstream (to the “right” on the DNA) of the termination codon. In eukaryotes, there is usually a “polyadenylation” sequence (AAU ...
... prokaryotic and eukaryotic genes, transcription begins at a DNA sequence that is upstream (to the “left” on the DNA) of the first codon (i.e., at the promoter), and ends downstream (to the “right” on the DNA) of the termination codon. In eukaryotes, there is usually a “polyadenylation” sequence (AAU ...
splice sites at the termini generating a novel intron from a dSpm
... of both a2-ml elements should be a reflection of differences in the relevant cis-acting sequences necessary as substrates for excision. The dSpm element of the original state is an internal deletion derivative of the autonomous En/Spm element but has retained the highly structured ends that have bee ...
... of both a2-ml elements should be a reflection of differences in the relevant cis-acting sequences necessary as substrates for excision. The dSpm element of the original state is an internal deletion derivative of the autonomous En/Spm element but has retained the highly structured ends that have bee ...
The Non-LTR Retrotransposon Rex3 from the Fish Xiphophorus is
... 1997; Kazazian and Moran 1998). There are two major classes of transposable elements. Class II transposons move as DNA molecules into another site of the host genome. In contrast, class I retroelements transpose via an RNA intermediate. Complete retrotransposons encode a reverse transcriptase copyin ...
... 1997; Kazazian and Moran 1998). There are two major classes of transposable elements. Class II transposons move as DNA molecules into another site of the host genome. In contrast, class I retroelements transpose via an RNA intermediate. Complete retrotransposons encode a reverse transcriptase copyin ...
GenoWatch: a disease gene mining browser for association study
... Human association studies often involve a large number of genomic markers on different chromosome regions. Researchers use these markers to locate candidate regions, and then go through a series of bioinformatic analyses of the regions to find disease-associated candidate genes. Frequently, these bioi ...
... Human association studies often involve a large number of genomic markers on different chromosome regions. Researchers use these markers to locate candidate regions, and then go through a series of bioinformatic analyses of the regions to find disease-associated candidate genes. Frequently, these bioi ...
Isochores and Genes: Who`s in the Driver`s Seat?
... • but “lagged the retreat” still possible as isochores “unform” ...
... • but “lagged the retreat” still possible as isochores “unform” ...
Gene regulation and bacteriophage
... the host, clearing the area. Another important protein is encoded by cro, standing for control of repressor and other genes. The cI repressor blocks the expression of most lambda genes except itself, and Cro blocks the expression of cI. The workings of the switch are illustrated in Figure 5. The gen ...
... the host, clearing the area. Another important protein is encoded by cro, standing for control of repressor and other genes. The cI repressor blocks the expression of most lambda genes except itself, and Cro blocks the expression of cI. The workings of the switch are illustrated in Figure 5. The gen ...
GENETIC ENGINEERING
... isolated from the rest of the DNA. Then the isolated gene is inserted into a bacterial cell. The bacterial cells then divide and increase in number. All new bacteria possess the new gene which became spliced into the bacteria's own gene. As these bacteria grow in liquid cultures, they produce the de ...
... isolated from the rest of the DNA. Then the isolated gene is inserted into a bacterial cell. The bacterial cells then divide and increase in number. All new bacteria possess the new gene which became spliced into the bacteria's own gene. As these bacteria grow in liquid cultures, they produce the de ...
GENETIC ENGINEERING - PLASMIDS, EPISOMES
... Are sequences of DNA that can move or transpose themselves to new positions within the genome of a single cell. The mechanism of transposition can be either "copy and paste" or ...
... Are sequences of DNA that can move or transpose themselves to new positions within the genome of a single cell. The mechanism of transposition can be either "copy and paste" or ...
All Alus are approximately 300 bp in length and derive
... Alu Insert • Alu elements are found only in primates – the "monkey" branch of the evolutionary tree, which includes humans. So, all of the hundreds of thousands of Alu copies have accumulated in primates since their separation from other vertebrate groups about 65 million years ago. • Once an Alu i ...
... Alu Insert • Alu elements are found only in primates – the "monkey" branch of the evolutionary tree, which includes humans. So, all of the hundreds of thousands of Alu copies have accumulated in primates since their separation from other vertebrate groups about 65 million years ago. • Once an Alu i ...
Finding the Fault in Nick`s Genome – sp2015
... Nicholas was born October 2004, the fifth child in the family. Before his 2nd birthday, an abscess formed near his rectum. Over the next 3 years holes appeared in his colon and large intestine, and stool leaked into his abdomen. The symptoms resembled irritable bowel disease (IBD) or Crohn's disease ...
... Nicholas was born October 2004, the fifth child in the family. Before his 2nd birthday, an abscess formed near his rectum. Over the next 3 years holes appeared in his colon and large intestine, and stool leaked into his abdomen. The symptoms resembled irritable bowel disease (IBD) or Crohn's disease ...
Rethinking Gene Expression and Evolution (Nobel Lecture)
... cell division. These remarkably stable differentiation events can be maintained for the entire life of an organism without any underlying changes in the DNA sequence. The germline cells, which in C. elegans inherit PIE-1 protein, are the only cells that retain the potential to launch the development ...
... cell division. These remarkably stable differentiation events can be maintained for the entire life of an organism without any underlying changes in the DNA sequence. The germline cells, which in C. elegans inherit PIE-1 protein, are the only cells that retain the potential to launch the development ...
Do the constraints of human speciation cause
... workshops, new and already known entities are listed (Lubs et al., 1999). The disproportionate effect of the X chromosome on mental performance is reflected by the last listing of 178 entities. Mental performance directs human behavior, and it is not surprising that this is the most attractive chara ...
... workshops, new and already known entities are listed (Lubs et al., 1999). The disproportionate effect of the X chromosome on mental performance is reflected by the last listing of 178 entities. Mental performance directs human behavior, and it is not surprising that this is the most attractive chara ...
Complete genome sequence of Roseophage vB_DshP
... vRNAP gene. This vRNAP is a unique feature in N4 phages putatively conducting early transcription of infective processes. Aligning DNA polymerases of all N4 phages, which are commonly applied as one of the viral phylogenetic markers [26, 27], phage vB_DshP-R1 is shown to cluster closely with four ma ...
... vRNAP gene. This vRNAP is a unique feature in N4 phages putatively conducting early transcription of infective processes. Aligning DNA polymerases of all N4 phages, which are commonly applied as one of the viral phylogenetic markers [26, 27], phage vB_DshP-R1 is shown to cluster closely with four ma ...
Imprinted green beards: a little less than kin and more than kind
... allele A8 that retains the mesiRNA but is insensitive to its effects and an allele A* that encodes a new mesiRNA (lower right). Subscripts m and p indicate madumnal and padumnal alleles. Squares represent the coding sequence of an mRNA. Circles and triangles represent coding sequences of mesiRNAs. F ...
... allele A8 that retains the mesiRNA but is insensitive to its effects and an allele A* that encodes a new mesiRNA (lower right). Subscripts m and p indicate madumnal and padumnal alleles. Squares represent the coding sequence of an mRNA. Circles and triangles represent coding sequences of mesiRNAs. F ...
Cell - David Page Lab
... Recent papers by David Page and his collaborators present an intriguing new face to the human Y chromosome, including eight massive palindromic arrays, most of which contain multi-copy pairs of testis-specific genes. Sequence pairs within the arms of these palindromic sequences retain a high degree ...
... Recent papers by David Page and his collaborators present an intriguing new face to the human Y chromosome, including eight massive palindromic arrays, most of which contain multi-copy pairs of testis-specific genes. Sequence pairs within the arms of these palindromic sequences retain a high degree ...
Gene duplication and divergence in the early evolution of
... length of time of divergence. With this in mind, it may be impossible to test definitively which process was most significant in early vertebrate evolution. An alternative approach is to examine similar, more recent evolutionary events and extrapolate these findings to the origin of vertebrates. For ...
... length of time of divergence. With this in mind, it may be impossible to test definitively which process was most significant in early vertebrate evolution. An alternative approach is to examine similar, more recent evolutionary events and extrapolate these findings to the origin of vertebrates. For ...
ppt_I
... ~96% (99.999% accurate) 30-40% repetitive elements (eg Alpha satellite, Alu repeats) All known genes, correctly identified (99.74%) heterochromatin ~4% grey ...
... ~96% (99.999% accurate) 30-40% repetitive elements (eg Alpha satellite, Alu repeats) All known genes, correctly identified (99.74%) heterochromatin ~4% grey ...
Transposable element
A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.