Functional genomics and gene chips
... healthy and diseased. Most studies applying microarrays are functional genomic studies. Not all of the transcribed genes will result in a protein. Also, practically all proteins are modified after the first assembly of amino acids. It is estimated that a protein derived from the same gene strand can ...
... healthy and diseased. Most studies applying microarrays are functional genomic studies. Not all of the transcribed genes will result in a protein. Also, practically all proteins are modified after the first assembly of amino acids. It is estimated that a protein derived from the same gene strand can ...
Transcription of a genome
... complexity of an organism is not necessarily related to its genome size (C-value). Transcription of a genome Only 5% of human and mouse genomes are conserved – this includes nearly all protein coding genes and a substantial number of genes for non-coding RNAs The remaining 95% of the human and mouse ...
... complexity of an organism is not necessarily related to its genome size (C-value). Transcription of a genome Only 5% of human and mouse genomes are conserved – this includes nearly all protein coding genes and a substantial number of genes for non-coding RNAs The remaining 95% of the human and mouse ...
Comparing DNA Sequences to Understand Evolutionary
... Project were able to identify and map the 20,000–25,000 genes that define a human being. The project also successfully mapped the genomes of other species, including the fruit fly, mouse, and Escherichia coli. The location and complete sequence of the genes in each of these species are available for ...
... Project were able to identify and map the 20,000–25,000 genes that define a human being. The project also successfully mapped the genomes of other species, including the fruit fly, mouse, and Escherichia coli. The location and complete sequence of the genes in each of these species are available for ...
Bio 211 Genetics Laboratory Experiment 5: Bioinformatics
... based approaches. Through program algorithms, coding sequences, promoters, and other functional DNA sequences can be identified from databases of genomic information, and interspecific comparisons can be made to address evolutionary relationships. One of the most widely‐used in silico (in silic ...
... based approaches. Through program algorithms, coding sequences, promoters, and other functional DNA sequences can be identified from databases of genomic information, and interspecific comparisons can be made to address evolutionary relationships. One of the most widely‐used in silico (in silic ...
Document
... http://www.ncbi.nlm.nih.gov/BLAST/download.shtml) Direction for use of these tools is available at the above sites and is beyond the scope of this tutorial For a small number of BLASTs, you can use web-based methods and common programs such as Word and Excel plus any of a number of downloadable tree ...
... http://www.ncbi.nlm.nih.gov/BLAST/download.shtml) Direction for use of these tools is available at the above sites and is beyond the scope of this tutorial For a small number of BLASTs, you can use web-based methods and common programs such as Word and Excel plus any of a number of downloadable tree ...
Linkage arrangement in the vitellogenin gene family of Xenopus
... Figure 2 Genotype, with respect to the gene Al, A2 and B2 polymorphisms, of the male and female parental animals, as well as of three of their offspring. 10 ug of genomic DNA prepared from erythrocytes (parental animals) or from whole tadpoles at stage 60-64 (offspring) were digested by EcoRI (genes ...
... Figure 2 Genotype, with respect to the gene Al, A2 and B2 polymorphisms, of the male and female parental animals, as well as of three of their offspring. 10 ug of genomic DNA prepared from erythrocytes (parental animals) or from whole tadpoles at stage 60-64 (offspring) were digested by EcoRI (genes ...
Presentazione di PowerPoint
... In silico analysis of such data will be crucial for understanding it (secondary ...
... In silico analysis of such data will be crucial for understanding it (secondary ...
- CSHL Institutional Repository
... All searches are case insensitive and are surrounded by wild cards. A query will return a database page if there is only one result, but more often it will return a table with multiple results. For example, for a sequence feature search, the table will contain the name of each sequence feature linke ...
... All searches are case insensitive and are surrounded by wild cards. A query will return a database page if there is only one result, but more often it will return a table with multiple results. For example, for a sequence feature search, the table will contain the name of each sequence feature linke ...
Document - Fan Lab
... This program can be used to compute ka/ks ratio between the genes in one well-annotated genome and their ortholog sequences in another closely related genome, which hasn’t been annotated. The result a) can be used to compute the diverge time between two species through estimating average Ks and muta ...
... This program can be used to compute ka/ks ratio between the genes in one well-annotated genome and their ortholog sequences in another closely related genome, which hasn’t been annotated. The result a) can be used to compute the diverge time between two species through estimating average Ks and muta ...
cDNA Sequences of Three Kinds of /3
... R2242) were determined. Southern hybridization indicated that these /3-tubulins consist of one gene family. Using RFLP mapping, these three /3-tubulin cDNAs were mapped to different chromosomes indicating at least three loci for the /3-tubulin gene. The deduced amino acid sequences of these cDNAs sh ...
... R2242) were determined. Southern hybridization indicated that these /3-tubulins consist of one gene family. Using RFLP mapping, these three /3-tubulin cDNAs were mapped to different chromosomes indicating at least three loci for the /3-tubulin gene. The deduced amino acid sequences of these cDNAs sh ...
Intraspecies variation in bacterial genomes: the need for a
... part of the genome, but others carry genes that make chromosome can then be cut into large-sized fragthem important for cell survival. There are also ments with fixed-reference terminal loci, allowing groups of genes found in the chromosome of some comparison of fragments with the same end points st ...
... part of the genome, but others carry genes that make chromosome can then be cut into large-sized fragthem important for cell survival. There are also ments with fixed-reference terminal loci, allowing groups of genes found in the chromosome of some comparison of fragments with the same end points st ...
Evolution Big Idea 1 Investigation 3 BLAST lab
... available for anyone in the world to access via the Internet. Why is this information important? Being able to identify the precise location and sequence of human genes will allow us to better understand genetic diseases. In addition, learning about the sequence of genes in other species helps us to ...
... available for anyone in the world to access via the Internet. Why is this information important? Being able to identify the precise location and sequence of human genes will allow us to better understand genetic diseases. In addition, learning about the sequence of genes in other species helps us to ...
Lecture 12 - School of Science and Technology
... • The best average of error (false-positive + false-negative) rate for either donor or acceptor site prediction is about 5%. This may be acceptable if the search is restricted by a short region. However search of a large region leads to unacceptable rate of the false-positive because for every true ...
... • The best average of error (false-positive + false-negative) rate for either donor or acceptor site prediction is about 5%. This may be acceptable if the search is restricted by a short region. However search of a large region leads to unacceptable rate of the false-positive because for every true ...
transcript
... • Several new -factors displace the vegetative -factor from the polymerase core and direct the transcription of sporulation genes • Each -factor has its own preferred promoter sequence ...
... • Several new -factors displace the vegetative -factor from the polymerase core and direct the transcription of sporulation genes • Each -factor has its own preferred promoter sequence ...
THE CHASM BETWEEN THE HUMAN AND CHIMPANZEE GENOMES
... A major problem with this type of selective analysis is that nearly all of the entire genome is now believed to be functional, as stated in the recent ENCODE project consortium reports (2012). The non-coding regions have been shown to provide many critical control features and nucleotide templates ( ...
... A major problem with this type of selective analysis is that nearly all of the entire genome is now believed to be functional, as stated in the recent ENCODE project consortium reports (2012). The non-coding regions have been shown to provide many critical control features and nucleotide templates ( ...
Chapter 08 Lecture PowerPoint
... • Several new -factors displace the vegetative -factor from the polymerase core and direct the transcription of sporulation genes • Each -factor has its own preferred promoter sequence ...
... • Several new -factors displace the vegetative -factor from the polymerase core and direct the transcription of sporulation genes • Each -factor has its own preferred promoter sequence ...
Junk DNA indicted - Creation Ministries International
... performs an RNA-only function. Moreover, its function is completely different from that of its peptide-encoding paralogous (counterpart) gene. This is no fluke. There are two snail pseudogenes that are, respectively, functional in spite of being unable to code for a full-length protein, or for any p ...
... performs an RNA-only function. Moreover, its function is completely different from that of its peptide-encoding paralogous (counterpart) gene. This is no fluke. There are two snail pseudogenes that are, respectively, functional in spite of being unable to code for a full-length protein, or for any p ...
locomotion in a consanguineous kindred the gene
... Department of Physiology, Cukurova University Faculty of Medicine, Adana 01330, Turkey The biological basis for the development of the cerebro-cerebellar structures required for posture and gait in humans is poorly understood. We investigated a large consanguineous family from Turkey exhibiting an e ...
... Department of Physiology, Cukurova University Faculty of Medicine, Adana 01330, Turkey The biological basis for the development of the cerebro-cerebellar structures required for posture and gait in humans is poorly understood. We investigated a large consanguineous family from Turkey exhibiting an e ...
1.5MB - Whitehead Institute for Biomedical Research
... Anchors (hundreds of bases with >90% identity) represent areas of evolutionary selection… …but only 30-40% of the highly conserved segments correspond to exons of genes!!! ...
... Anchors (hundreds of bases with >90% identity) represent areas of evolutionary selection… …but only 30-40% of the highly conserved segments correspond to exons of genes!!! ...
Using mouse genetics to understand human disease
... Anchors (hundreds of bases with >90% identity) represent areas of evolutionary selection… …but only 30-40% of the highly conserved segments correspond to exons of genes!!! ...
... Anchors (hundreds of bases with >90% identity) represent areas of evolutionary selection… …but only 30-40% of the highly conserved segments correspond to exons of genes!!! ...
Duplication
... Given an (optimal) alignment between two genome regions, you can ask what is the probability that they are (not) related by homology? Note that (when known) the answer is a function of the molecular distance between the two (eg, between two species) ...
... Given an (optimal) alignment between two genome regions, you can ask what is the probability that they are (not) related by homology? Note that (when known) the answer is a function of the molecular distance between the two (eg, between two species) ...
AP Bio DNA Sim Lab
... known as the Human Genome Project were able to identify and map the 20,000–25,000 genes that define a human being. The project also successfully mapped the genomes of other species, including the fruit fly, mouse, and Escherichia coli. The location and complete sequence of the genes in each of these ...
... known as the Human Genome Project were able to identify and map the 20,000–25,000 genes that define a human being. The project also successfully mapped the genomes of other species, including the fruit fly, mouse, and Escherichia coli. The location and complete sequence of the genes in each of these ...
Document
... TRANSFAC® is a database on eukaryotic cis-acting regulatory DNA elements and trans-acting factors. It covers the whole range from yeast to human. It started 1988 with a printed compilation and was transferred into computerreadable format in 1990. The FACTOR table contains 6133 entries in 50 classes, ...
... TRANSFAC® is a database on eukaryotic cis-acting regulatory DNA elements and trans-acting factors. It covers the whole range from yeast to human. It started 1988 with a printed compilation and was transferred into computerreadable format in 1990. The FACTOR table contains 6133 entries in 50 classes, ...
L - Centre for Genomic Regulation
... Orthology definition is purely on evolutionary terms (not functional, not synteny…) There is no limit on the number of orthologs or paralogs that a given gene can have (when more than one ortholog exist, there is nothing such as “the true ortholog”) Many-to-Many orthology relationships do exist (co- ...
... Orthology definition is purely on evolutionary terms (not functional, not synteny…) There is no limit on the number of orthologs or paralogs that a given gene can have (when more than one ortholog exist, there is nothing such as “the true ortholog”) Many-to-Many orthology relationships do exist (co- ...
Document
... than are at lower temperatures, indicating that the fungus is under heat stress. 2. More putative virulence genes (ex. those coding for the proteins responsive to oxidative stress and host immune system and for toxin production) are highly expressed at 37˚C, although there is no contact with host ce ...
... than are at lower temperatures, indicating that the fungus is under heat stress. 2. More putative virulence genes (ex. those coding for the proteins responsive to oxidative stress and host immune system and for toxin production) are highly expressed at 37˚C, although there is no contact with host ce ...
Transposable element
A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.