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Molecular and General Genetics
Molecular and General Genetics

... Support values for the internal branches are shown in percent. The lengths of selected branches are indicated in italics. The scale bar indicates the distances as calculated from the multiple alignment using CLUSTAL W. The unrooted tree results from the search by quartet puzzling and is shown using ...
Biochemistry
Biochemistry

... regulation of gene expression is essential to making optimal use of available energy. Adult tissue-specific stem cells have the capacity to self-renew and generate functional differentiated cells that replenish lost cells throughout an organism’s lifetime. ...
Decomposition of DNA Sequence Complexity
Decomposition of DNA Sequence Complexity

... of the spatial heterogeneity in symbolic sequences [1]. The most outstanding feature of SCC is that it increases with the level of detail in the description [2], thus fulfilling one of the key requirements for complexity measures [3]. Such a key feature is revealed by drawing the complexity profile, ...
File
File

... *Get lab folders organized. Due by the end of the school day.* HOMEWORK – DNA foldable. Due Tomorrow at the end of 4th period. CH 11 quiz corrections. Due in the tray by tomorrow beginning of period (see GC). ...
presentation - Genome-to-Genome Distance Calculator
presentation - Genome-to-Genome Distance Calculator

... Distance: 0.1661101 DDH estimate (regression­based): 76.7180478 Estimate of DDH <=70% (threshold­based): no (threshold=0.2676) ...
File
File

...  The first evidence for mobile DNA segments came from geneticist Barbara McClintock’s breeding experiments with Indian corn  McClintock identified changes in the color of corn kernels that made sense only if some genetic elements move from other genome locations into the genes for kernel color  T ...
Justification of Size Estimates for Tomato Genome Sequencing
Justification of Size Estimates for Tomato Genome Sequencing

... Additional Information. When the sequencing project is advanced to the stage where BAC contigs can be assayed for both total non-redundant sequence length and physical distance based on in situ hybridization, we will be able to develop an additional estimate of euchromatin physical size through vali ...
Document
Document

...  The first evidence for mobile DNA segments came from geneticist Barbara McClintock’s breeding experiments with Indian corn  McClintock identified changes in the color of corn kernels that made sense only if some genetic elements move from other genome locations into the genes for kernel color  T ...
DNA, RNA, and Snorks
DNA, RNA, and Snorks

... Fun with Translation! DNA, RNA, and Snorks ...
Page 517 Duplication of the S. cerevisiae genome
Page 517 Duplication of the S. cerevisiae genome

... can compensate for mutations: via genes with overlapping functions (e.g. paralogs), or via genes with unrelated functions that participate in regulatory networks. He reported that overall, gene duplications did not provide robustness. Instead, interactions among unrelated genes provide robustness ag ...
Independent specialization of the human and mouse X
Independent specialization of the human and mouse X

... 11.5 Mb of sequence generated, 3.15 Mb comprised X-chromosomal genes (13/144 in humans and 29/197 in mice) that violated Ohno’s amplicons. We estimated the total size of the human X chromosome to law were present because of duplication of an ancestral X-linked gene be about 155.3 Mb, of which ~2% wa ...
Yu-GO
Yu-GO

... coordinated at the transcription level, there is a need to study the between-unit expressional relationship directly. Results: We approach this issue by constructing an index of correlation function to convey the global pattern of coexpression between genes from one process and genes from the entire ...
Flatworms and Evolution
Flatworms and Evolution

... “We are asked to believe that the Turbellaria have lost their coelom, their anus, lost their nephrostomes. This is asking too much of one’s ...
Complete Mitochondrial DNA Sequence and Amino Acid Analysis of
Complete Mitochondrial DNA Sequence and Amino Acid Analysis of

... AF390098; Liverpool AeCOI, AY056596; Formosus AeCOI, AY056597 and Moyo-R AeCOI, AF380835. Comparative studies of mitochondrial DNA (mtDNA) among different groups have revealed an overall well conserved organization across metazoa but significant differences also exist. For example, compared to verte ...
Exploring a fatal outbreak of Escherichia coli using
Exploring a fatal outbreak of Escherichia coli using

... 8. This will filter the table on the right hand side to show all the genomes that were either isolated in Germany, or had that word mentioned in the information that was submitted when the genome became public. Other information about these genomes can be seen in the columns, including information l ...
Intra-genomic 16S rRNA gene heterogeneity in
Intra-genomic 16S rRNA gene heterogeneity in

... may, therefore, be a consequence of specialized organisms living in a uniform environment. 16S rRNA gene heterogeneity In total, 62.7% of all cyanobacterial genomes and 64.3% of filamentous forms contained more than one ribosomal operon (Table 1). Among these 37 cyanobacterial genomes with multiple ...
Document
Document

... • t - reversal distance between p and s • d(p, s) = smallest possible value of t, given p, s ...
Sex chromosome-to-autosome transposition - David Page Lab
Sex chromosome-to-autosome transposition - David Page Lab

... Background: Although the mammalian X and Y chromosomes evolved from a single pair of autosomes, they are highly differentiated: the Y chromosome is dramatically smaller than the X and has lost most of its genes. The surviving genes are a specialized set with extraordinary evolutionary longevity. Mos ...
repetitive extragenic palindromic sequences in pseudomonas
repetitive extragenic palindromic sequences in pseudomonas

... with respect to the sequenced genomes it is an exceptional candidate for use as a fingerprint in precise genotyping and epidemiological studies P. syringae is an agriculturally important plant pathogen with at least 50 pathovars based on host specificity. P. syringae enters plant leaves through stom ...
High-throughput reverse genetics: RNAi screens in
High-throughput reverse genetics: RNAi screens in

... clones were known before the screen. On chromosome III, 281 genes with a phenotype were found (86 previously known). In total, 12.9-13.9% of tested genes yielded a phenotype in the two screens, suggesting that the methods were about equally efficient in capturing gene function. As one might expect, ...
PDF - Oxford Academic - Oxford University Press
PDF - Oxford Academic - Oxford University Press

... representative of the import set (figs. 1b and 2 and supplementary fig. S1, Supplementary Material online). In fact, most of the genes reported by NS as acquired at the origins of a MAL are present in very few species in Archaea and Bacteria. More precisely, 52% (1,171/2,264 import clusters) are rep ...
video slide
video slide

... introns and gene-related regulatory sequences • Intergenic DNA is noncoding DNA found between genes – Pseudogenes are former genes that have accumulated mutations and are nonfunctional – Repetitive DNA is present in multiple copies in the genome ...
Alu Background Information
Alu Background Information

... Alu elements are found only in primates – the "monkey" branch of the evolutionary tree, which includes humans. So, all of the hundreds of thousands of Alu copies have accumulated in primates since their separation from other vertebrate groups about 65 million years ago. Once an Alu integrates into a ...
Slide 1
Slide 1

... - Telomeres in Drosophila are transposable elements that copy themselves and add sections, maintaining the length of their telomeres. Tn transposons in bacteria transfer antibiotic genes. - Transposons create homologous regions that increase the liklihood of recombination - and the unequal cross-ove ...
PPT - Blumberg Lab
PPT - Blumberg Lab

... • 21 was rich in rRNA genes so made a radiation hybrid panel from patient • Identified hybrid cell carrying the breakpoint – made a genomic library from it • Screened library for clones with both rRNA genes and X chromosome specific sequences – Long, tedious process with many more failures than succ ...
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Transposable element



A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.
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