Lecture 4
... • 2000 first draft of genome published • More than 200,000 expressed sequence tags available • Large scale transposon mutagenesis • Flybase: computer database and resource ...
... • 2000 first draft of genome published • More than 200,000 expressed sequence tags available • Large scale transposon mutagenesis • Flybase: computer database and resource ...
multicopy gene family evolution on primate y chromosomes
... Contrary to previous theories, the Y chromosome is an important determinant of male phenotype [15–17]. The Y chromosome has been found to be associated with male fertility in humans [18] and even less obvious traits like lifespan [19] and locomotive activity [20] in Drosophila species. Therefore, an ...
... Contrary to previous theories, the Y chromosome is an important determinant of male phenotype [15–17]. The Y chromosome has been found to be associated with male fertility in humans [18] and even less obvious traits like lifespan [19] and locomotive activity [20] in Drosophila species. Therefore, an ...
Anterior boundaries of Hox gene expression in mesoderm
... els of Hox 1.1 transcripts are detected in RNAs from embryos at 12 days post coitum (P.c.) and multiple transcripts are found in adult testis, kidney, brain, and ovary [q.Restricted transcription of the Hox 1.3 gene to thoracic sclerotomes, as well as tissues derived from or induced by thoracic meso ...
... els of Hox 1.1 transcripts are detected in RNAs from embryos at 12 days post coitum (P.c.) and multiple transcripts are found in adult testis, kidney, brain, and ovary [q.Restricted transcription of the Hox 1.3 gene to thoracic sclerotomes, as well as tissues derived from or induced by thoracic meso ...
Primer on Molecular Biology
... More Terminology • The genome is an organism’s complete set of DNA. ...
... More Terminology • The genome is an organism’s complete set of DNA. ...
Primer on Molecular Biology
... More Terminology • The genome is an organism’s complete set of DNA. ...
... More Terminology • The genome is an organism’s complete set of DNA. ...
UCSD_PevznerMolecula.. - Purdue University :: Computer Science
... More Terminology • The genome is an organism’s complete set of DNA. ...
... More Terminology • The genome is an organism’s complete set of DNA. ...
Patent constraints
... polypeptides in plants" which also includes continuations called "Yield related genes in plants", "environmental stress tolerance genes", etc all claiming priority to a series of 1998 "bulk sequence applications". While these 1998 applications themselves are not published, it can be inferred from th ...
... polypeptides in plants" which also includes continuations called "Yield related genes in plants", "environmental stress tolerance genes", etc all claiming priority to a series of 1998 "bulk sequence applications". While these 1998 applications themselves are not published, it can be inferred from th ...
Genome-wide characteristics of sequence coverage by next
... “The most likely explanation for why genes for common diseases have not been found is that, with few exceptions, they do not exist. …., if inherited genes are not to blame for our commonest illnesses, can we find out what is? “ ...
... “The most likely explanation for why genes for common diseases have not been found is that, with few exceptions, they do not exist. …., if inherited genes are not to blame for our commonest illnesses, can we find out what is? “ ...
Snorks Lab File
... protein molecules and that this is virtually the same mechanism for all life forms. ...
... protein molecules and that this is virtually the same mechanism for all life forms. ...
29th International Conference on Animal Genetics ISAG2004/TOKYO
... Construction of a high resolution comparative gene map between human chromosome 14 and swine chromosomes using RH mapping. Hiroshi Yasue (National Institute of Agrobiological Sciences) ...
... Construction of a high resolution comparative gene map between human chromosome 14 and swine chromosomes using RH mapping. Hiroshi Yasue (National Institute of Agrobiological Sciences) ...
A Single Eubacterial Origin of Eukaryotic
... David S. Horner, Robert P. Hirt, and T. Martin Embley Department of Zoology, Natural History Museum, London, England The iron sulfur protein pyruvate:ferredoxin oxidoreductase (PFO) is central to energy metabolism in amitochondriate eukaryotes, including those with hydrogenosomes. Thus, revealing th ...
... David S. Horner, Robert P. Hirt, and T. Martin Embley Department of Zoology, Natural History Museum, London, England The iron sulfur protein pyruvate:ferredoxin oxidoreductase (PFO) is central to energy metabolism in amitochondriate eukaryotes, including those with hydrogenosomes. Thus, revealing th ...
Transvection and pairing of a Drosophila Hox long noncoding RNA
... 1995). This region is also associated with numerous mutations resulting in a dominant gain of function (GOF) Scr homeotic transformation, whereby sex combs (normally specific to the male T1 leg) are ectopically formed on legs of the T2 and T3 segments (Pattatucci et al. 1991). Strikingly, five diffe ...
... 1995). This region is also associated with numerous mutations resulting in a dominant gain of function (GOF) Scr homeotic transformation, whereby sex combs (normally specific to the male T1 leg) are ectopically formed on legs of the T2 and T3 segments (Pattatucci et al. 1991). Strikingly, five diffe ...
Properties of Mitotic and Meiotic Recombination in the
... recombination in the CUP1 array; recombination events that delete the URA3 insertion from the CUP1 array occur at a rate of >10-3/division in unselected cells. This rate is almost three orders of magnitude higher than observed for mitotic recombination events involving single-copy genes. In summary, ...
... recombination in the CUP1 array; recombination events that delete the URA3 insertion from the CUP1 array occur at a rate of >10-3/division in unselected cells. This rate is almost three orders of magnitude higher than observed for mitotic recombination events involving single-copy genes. In summary, ...
Telomere maintenance without telomerase
... recombination, as the appearance of survivors was blocked if the est1-D strain was also defective for RAD52, which is responsible for the majority of homologous recombination events in yeast. Survivors could be grouped into two general classes based on the pattern of ampli®cation of telomeric and/or ...
... recombination, as the appearance of survivors was blocked if the est1-D strain was also defective for RAD52, which is responsible for the majority of homologous recombination events in yeast. Survivors could be grouped into two general classes based on the pattern of ampli®cation of telomeric and/or ...
SVPaper050711
... yields 117 deletions. Assuming that this region is typical, the rest of the genome (in classical laboratory strains) will contain approximately 49,000 deletions in this size range. Table 1 classifies SVs greater than 100 bp into two groups: 99.4% are simple and 0.6% are complex. Simple SVs include t ...
... yields 117 deletions. Assuming that this region is typical, the rest of the genome (in classical laboratory strains) will contain approximately 49,000 deletions in this size range. Table 1 classifies SVs greater than 100 bp into two groups: 99.4% are simple and 0.6% are complex. Simple SVs include t ...
STRIVE Report Series No.65
... strains have been well characterised for their ability to degrade this molecule, particularly members of the genus Pseudomonas. There is also now considerable interest in examining ways to convert some of the styrene-based products, such as polystyrene, back to styrene monomers which may subsequentl ...
... strains have been well characterised for their ability to degrade this molecule, particularly members of the genus Pseudomonas. There is also now considerable interest in examining ways to convert some of the styrene-based products, such as polystyrene, back to styrene monomers which may subsequentl ...
Evolutionary dynamics of nematode operons
... genes reside in over 1100 operons in the model organism Caenorhabditis elegans. It is unclear how operons have become abundant in nematode genomes. The “one-way street” hypothesis asserts that once formed by chance, operons are very difficult to break, because the breakage would leave downstream gen ...
... genes reside in over 1100 operons in the model organism Caenorhabditis elegans. It is unclear how operons have become abundant in nematode genomes. The “one-way street” hypothesis asserts that once formed by chance, operons are very difficult to break, because the breakage would leave downstream gen ...
ARTICLES - Weizmann Institute of Science
... Indeed, several types of regions had markedly high or low predicted occupancy. The highest predicted occupancy was over centromeres, indicating that centromere function requires enhanced stability of histone–DNA interactions that are encoded in the genomic sequence. One might think that genomes woul ...
... Indeed, several types of regions had markedly high or low predicted occupancy. The highest predicted occupancy was over centromeres, indicating that centromere function requires enhanced stability of histone–DNA interactions that are encoded in the genomic sequence. One might think that genomes woul ...
Computational Definition of
... constitutively spliced exons. We focused on constitutive splicing as opposed to alternative splicing so as to tackle the more fundamental problem represented by the former and to avoid what are likely more complex mechanisms in the latter. The strategy we used to overcome the confounding presence of ...
... constitutively spliced exons. We focused on constitutive splicing as opposed to alternative splicing so as to tackle the more fundamental problem represented by the former and to avoid what are likely more complex mechanisms in the latter. The strategy we used to overcome the confounding presence of ...
Opsin genes, cone photopigments, color vision, and color blindness
... in the outer segments of the cone photoreceptor cells (left). Each molecule consists of a transmembrane opsin bound to a chromophore, 11-cis-retinal. The opsin or protein portion of the molecule is a chain of amino acids, running from an amino-terminal end (N), exposed on the external aqueous surfac ...
... in the outer segments of the cone photoreceptor cells (left). Each molecule consists of a transmembrane opsin bound to a chromophore, 11-cis-retinal. The opsin or protein portion of the molecule is a chain of amino acids, running from an amino-terminal end (N), exposed on the external aqueous surfac ...
Imprinting in the endosperm: a possible role in preventing wide
... placenta, are regulated by a range of epigenetic mechanisms that are globally termed imprinting. Imprinted genes are characterized by their uniparental expression, the other parental allele being silenced. Normal development of the endosperm thus requires a highly specific balance of gene expression ...
... placenta, are regulated by a range of epigenetic mechanisms that are globally termed imprinting. Imprinted genes are characterized by their uniparental expression, the other parental allele being silenced. Normal development of the endosperm thus requires a highly specific balance of gene expression ...
Codon usage bias from tRNA`s point of view
... species. Surprisingly, despite the wide G+C variation of bacterial genomes these anticodons are the same in most genomes. This suggests an optimization of the translation machinery to use a small subset of optimal codons and anticodons in fast-growing bacteria and in highly expressed genes. As a res ...
... species. Surprisingly, despite the wide G+C variation of bacterial genomes these anticodons are the same in most genomes. This suggests an optimization of the translation machinery to use a small subset of optimal codons and anticodons in fast-growing bacteria and in highly expressed genes. As a res ...
Tracing the Thread of Plastid Diversity through the Tapestry of Life
... Herrmann 1998). Those plastid proteins not encoded in the plastid genome are encoded in the nuclear genome and must be targeted to the plastid. Three mechanisms underlie this reduction of the plastid genome; gene loss, substitution, and transfer. First, in the case of gene loss, genes that no longer ...
... Herrmann 1998). Those plastid proteins not encoded in the plastid genome are encoded in the nuclear genome and must be targeted to the plastid. Three mechanisms underlie this reduction of the plastid genome; gene loss, substitution, and transfer. First, in the case of gene loss, genes that no longer ...
Chromosomes Carrying Meiotic Avoidance Loci
... et al., 2004; Conner et al., 2008). By contrast, two independent dominant loci control apomixis in Hieracium praealtum. Genetic markers linked to these loci have been determined using a deletion mapping approach (Catanach et al., 2006). The roles of these two loci and their interactions with the sex ...
... et al., 2004; Conner et al., 2008). By contrast, two independent dominant loci control apomixis in Hieracium praealtum. Genetic markers linked to these loci have been determined using a deletion mapping approach (Catanach et al., 2006). The roles of these two loci and their interactions with the sex ...
Transposable element
A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.