PDF
... Although many of the regulatory hierarchies governing development have been elucidated, progress has been slow in identifying the direct targets of the terminal regulatory genes in these hierarchies. These difficulties arise from: (1) few target genes being unique to one hierarchy; (2) difficulties ...
... Although many of the regulatory hierarchies governing development have been elucidated, progress has been slow in identifying the direct targets of the terminal regulatory genes in these hierarchies. These difficulties arise from: (1) few target genes being unique to one hierarchy; (2) difficulties ...
Science-2004-Tong-808-13 - San Diego Center for Systems Biology
... was mapped by crossing mutations in 132 different query genes into a set of ⬃4700 viable gene yeast deletion mutants and scoring the double mutant progeny for fitness defects. Network connectivity was predictive of function because interactions often occurred among functionally related genes, and sim ...
... was mapped by crossing mutations in 132 different query genes into a set of ⬃4700 viable gene yeast deletion mutants and scoring the double mutant progeny for fitness defects. Network connectivity was predictive of function because interactions often occurred among functionally related genes, and sim ...
Substitution Rates in a New Silene latifolia Sex
... significantly faster accumulation of nonsynonymous substitutions, which is consistent with the theoretical prediction of relaxed purifying selection in Y-linked genes, leading to the accumulation of nonsynonymous substitutions and genetic degeneration of the Y-linked genes. ...
... significantly faster accumulation of nonsynonymous substitutions, which is consistent with the theoretical prediction of relaxed purifying selection in Y-linked genes, leading to the accumulation of nonsynonymous substitutions and genetic degeneration of the Y-linked genes. ...
Gene ORGANizer: linking genes to the organs they
... Many high-throughput methods such as whole-genome sequencing, expression microarrays, RNA-seq, and wholegenome methylation mapping produce genome-wide data whose analyses produce long lists of genes of interest. These lists typically include genes that share a certain trait such as being bound by th ...
... Many high-throughput methods such as whole-genome sequencing, expression microarrays, RNA-seq, and wholegenome methylation mapping produce genome-wide data whose analyses produce long lists of genes of interest. These lists typically include genes that share a certain trait such as being bound by th ...
Comparative analysis of the Geobacillus hemicellulose utilization locus reveals a highly
... there has been increasing interest in the use of microorganisms and their enzymes for the hydrolysis of hemicelluloses, as a result of the various biotechnological and industrial applications in which the hydrolytic enzymes, the hemicelluloytic process and its products can be exploited. For example, ...
... there has been increasing interest in the use of microorganisms and their enzymes for the hydrolysis of hemicelluloses, as a result of the various biotechnological and industrial applications in which the hydrolytic enzymes, the hemicelluloytic process and its products can be exploited. For example, ...
Greedy Algorithms
... At each of the following t-2 iterations, finds a “best” l-mer in sequence i from the perspective of the already constructed (i-1) x l alignment matrix for the first (i-1) sequences In other words, it finds an l-mer in sequence i maximizing Score(s,i,DNA) ...
... At each of the following t-2 iterations, finds a “best” l-mer in sequence i from the perspective of the already constructed (i-1) x l alignment matrix for the first (i-1) sequences In other words, it finds an l-mer in sequence i maximizing Score(s,i,DNA) ...
et al.
... Cells transformed by electroporation can be selected on the surface of solid media, thus facilitating subsequent manipulation. Both the spheroplast technique and electroporation have been applied to a wide range of yeasts and filamentous fungi. ...
... Cells transformed by electroporation can be selected on the surface of solid media, thus facilitating subsequent manipulation. Both the spheroplast technique and electroporation have been applied to a wide range of yeasts and filamentous fungi. ...
Comprehensive Cardiomyopathy Panel
... sarcomere and cytoskeleton. DCM Dilated Cardiomyopathy (DCM) is characterized by left ventricular enlargement and systolic dysfunction. DCM can either be acquired though environmental causes (most commonly through ischemic injury following myocardial infarction or coronary artery disease), or can be ...
... sarcomere and cytoskeleton. DCM Dilated Cardiomyopathy (DCM) is characterized by left ventricular enlargement and systolic dysfunction. DCM can either be acquired though environmental causes (most commonly through ischemic injury following myocardial infarction or coronary artery disease), or can be ...
RESEARCH ARTICLES
... Consequently, most of the cassettes were designed and synthesized based on the CP001621 sequence (11). When it was finished, we chose the sequence of the genome successfully transplanted from yeast (CP001668) as our design reference (except that we kept the intact typeIIIres gene). All differences t ...
... Consequently, most of the cassettes were designed and synthesized based on the CP001621 sequence (11). When it was finished, we chose the sequence of the genome successfully transplanted from yeast (CP001668) as our design reference (except that we kept the intact typeIIIres gene). All differences t ...
Section 11–3 Exploring Mendelian Genetics
... shape segregate independently of those for seed color? He observed F2 offspring that had combinations of phenotypes—and therefore combinations of alleles—not found in either parent. ...
... shape segregate independently of those for seed color? He observed F2 offspring that had combinations of phenotypes—and therefore combinations of alleles—not found in either parent. ...
Section 11–3 Exploring Mendelian Genetics (pages 270–274)
... shape segregate independently of those for seed color? He observed F2 offspring that had combinations of phenotypes—and therefore combinations of alleles—not found in either parent. ...
... shape segregate independently of those for seed color? He observed F2 offspring that had combinations of phenotypes—and therefore combinations of alleles—not found in either parent. ...
Microbiology
... Agar plates containing Azurine-Crosslinked (AZCL) polysaccharides (Megazyme) were prepared by adding 0.2 YOof the substrate to LB agar. Extracellular enzyme activity was indicated by liquefaction of the substrate particles around the colonies. Cellular fractions of E. coli transformed by recombinant ...
... Agar plates containing Azurine-Crosslinked (AZCL) polysaccharides (Megazyme) were prepared by adding 0.2 YOof the substrate to LB agar. Extracellular enzyme activity was indicated by liquefaction of the substrate particles around the colonies. Cellular fractions of E. coli transformed by recombinant ...
finding the genes that regulate development
... (2) The realisation that such genes and basic developmental events are extremely highly conserved through evolution. So observations made in one organism (e.g. Drosophila) have wider relevance to all animals (including humans). (3) The development of molecular techniques to manipulate developmental ...
... (2) The realisation that such genes and basic developmental events are extremely highly conserved through evolution. So observations made in one organism (e.g. Drosophila) have wider relevance to all animals (including humans). (3) The development of molecular techniques to manipulate developmental ...
PDF - Journal of Genomics
... evidence suggests that several amino acid biosynthetic pathways are shared between aphid and Buchnera, providing the aphid the ability to regulate the endosymbiont’s metabolism (16). No aphid species poses a greater threat to soybean yields in North America than the soybean aphid, Aphis glycines Mat ...
... evidence suggests that several amino acid biosynthetic pathways are shared between aphid and Buchnera, providing the aphid the ability to regulate the endosymbiont’s metabolism (16). No aphid species poses a greater threat to soybean yields in North America than the soybean aphid, Aphis glycines Mat ...
No Slide Title
... 2. The function requires a large amount of diversity. immunoglobulin and histocompatibility genes ...
... 2. The function requires a large amount of diversity. immunoglobulin and histocompatibility genes ...
Inferring Gene Regulatory Networks from Time
... elements Mij the estimated parameters being σ̂ 2 and the elements of the matrix Λ̂ that we allow to be nonzero. From this equation, we see that while the squared error decreases, the AIC may increase as the number of nonzero elements increases. A gene regulatory network may now be inferred from gene ...
... elements Mij the estimated parameters being σ̂ 2 and the elements of the matrix Λ̂ that we allow to be nonzero. From this equation, we see that while the squared error decreases, the AIC may increase as the number of nonzero elements increases. A gene regulatory network may now be inferred from gene ...
RefGen_v3_status_20120522
... the International Nucleotide Sequence Database Collaboration (INSDC), also known as DDBJ/EMBL/GenBank: 1) B73 RefGen_v2 pseudomolecule scaffold sequence and AGP (short for “A Golden Path”, the table that specifies how the component contigs are combined to build the pseudomolecule scaffold sequences) ...
... the International Nucleotide Sequence Database Collaboration (INSDC), also known as DDBJ/EMBL/GenBank: 1) B73 RefGen_v2 pseudomolecule scaffold sequence and AGP (short for “A Golden Path”, the table that specifies how the component contigs are combined to build the pseudomolecule scaffold sequences) ...
Slide 1
... To identify yeast gene products important for accurate chromosome transmission in mitosis. Importance: Errors during chromosome transmission in humans can lead to cell death, genetic disorders (e.g., Down Syndrome), and cancer. Experimental Strategy: Plasmids containing yeast genes that suppress ...
... To identify yeast gene products important for accurate chromosome transmission in mitosis. Importance: Errors during chromosome transmission in humans can lead to cell death, genetic disorders (e.g., Down Syndrome), and cancer. Experimental Strategy: Plasmids containing yeast genes that suppress ...
Analysis of Time-Series Gene Expression Data : Methods
... and the results to a great extent depend on the specific use of the method as well as the nature the type of data. • Methods should be evaluated and not compared, and evaluation could be problem dependent. ...
... and the results to a great extent depend on the specific use of the method as well as the nature the type of data. • Methods should be evaluated and not compared, and evaluation could be problem dependent. ...
CHAPTER 1: Introduction During the past century some major
... Neo-Darwinists thought that natural selection was the most important mechanism to explain evolution in the detriment of drift and other non-adaptive variation. In a first attempt to measure variation, two different models emerged. The ‘classical model’ supported the role of natural selection in pur ...
... Neo-Darwinists thought that natural selection was the most important mechanism to explain evolution in the detriment of drift and other non-adaptive variation. In a first attempt to measure variation, two different models emerged. The ‘classical model’ supported the role of natural selection in pur ...
Normalization between a pair of arrays
... Some regulatory proteins play targeted role i.e. they take part in regulation of a few genes. Some regulatory proteins play more general role in initiating transcription (for example the eukaryotic transcription factors of type II or the RNA polymerase itself that is essential for the transcription ...
... Some regulatory proteins play targeted role i.e. they take part in regulation of a few genes. Some regulatory proteins play more general role in initiating transcription (for example the eukaryotic transcription factors of type II or the RNA polymerase itself that is essential for the transcription ...
Fully automated pipeline for detection of sex linked genes using
... Background: Sex chromosomes present a genomic region which to some extent, differs between the genders of a single species. Reliable high-throughput methods for detection of sex chromosomes specific markers are needed, especially in species where genome information is limited. Next generation sequen ...
... Background: Sex chromosomes present a genomic region which to some extent, differs between the genders of a single species. Reliable high-throughput methods for detection of sex chromosomes specific markers are needed, especially in species where genome information is limited. Next generation sequen ...
Homeotic selector genes
... HOX-C genes specify a discrete combinatorial code that uniquely identified each cell in the body – called the HOX code – alterations in the HOX code cause predictable changes in patterning • loss-of-function cause anterior transformations • gain-of-function cause posterior transformations – since th ...
... HOX-C genes specify a discrete combinatorial code that uniquely identified each cell in the body – called the HOX code – alterations in the HOX code cause predictable changes in patterning • loss-of-function cause anterior transformations • gain-of-function cause posterior transformations – since th ...