Slide 1
... The Genevestigator analysis platform comprises a large database of manually curated microarray experiments collected from the public domain or from individual contributors. The array annotations necessary for data analysis were retrieved from public repositories and/or, if insufficiently available, ...
... The Genevestigator analysis platform comprises a large database of manually curated microarray experiments collected from the public domain or from individual contributors. The array annotations necessary for data analysis were retrieved from public repositories and/or, if insufficiently available, ...
Vilar et al. 2006, PLoS Computational Biology
... We aim towards a set of heuristic rules to identify the most “druggable” GPCRs and the best model species in which to conduct preclinical tests. By “druggable” it is meant those which possess any single or combination of characteristics favourable to drug development, such as: (1) conserved sequence ...
... We aim towards a set of heuristic rules to identify the most “druggable” GPCRs and the best model species in which to conduct preclinical tests. By “druggable” it is meant those which possess any single or combination of characteristics favourable to drug development, such as: (1) conserved sequence ...
lecture9 - Stanford AI Lab
... one or more reads that map to the exact same 50 and 30 positions in the genome When identifying miRNAs in data from sea squirts, known to harbor large numbers of non-canonical miRNAs, the first version of miRDeep only reports 46 known and 31 novel miRNAs. In contrast, miRDeep2 reports 313 known and ...
... one or more reads that map to the exact same 50 and 30 positions in the genome When identifying miRNAs in data from sea squirts, known to harbor large numbers of non-canonical miRNAs, the first version of miRDeep only reports 46 known and 31 novel miRNAs. In contrast, miRDeep2 reports 313 known and ...
Solutions for Recombinant DNA Unit Exam
... 3. The yeast pathway may not be the same as the bacterial pathway. Or, different genes are required for the same job in different species. 4. Many eukaryotic proteins have post-translational modifications. 5. The mutation may be in a different gene. 6. Proteins may be structurally different between ...
... 3. The yeast pathway may not be the same as the bacterial pathway. Or, different genes are required for the same job in different species. 4. Many eukaryotic proteins have post-translational modifications. 5. The mutation may be in a different gene. 6. Proteins may be structurally different between ...
Investigation 1: Identify the Transcriptional Unit
... RNA polymerase binds to the promoter sequence on the template strand, constructing the transcribed mRNA in the direction, just like the coding DNA strand that you see on the tracks. In fact, polymerases can only add nucleotides to the 3’ end (free – OH) of the growing RNA molecule. Termination of mR ...
... RNA polymerase binds to the promoter sequence on the template strand, constructing the transcribed mRNA in the direction, just like the coding DNA strand that you see on the tracks. In fact, polymerases can only add nucleotides to the 3’ end (free – OH) of the growing RNA molecule. Termination of mR ...
Supplemental Figure Legends
... Carboplatin and Carboplatin+ABT888 treated tumors was used to adjust the GenePix arrays. Principle component analysis (A) before normalization and (B) after normalization are shown. Supplemental Figure S3. Diagram of each dataset’s analysis to arrive at the consensus list of 38 commonly regulated ge ...
... Carboplatin and Carboplatin+ABT888 treated tumors was used to adjust the GenePix arrays. Principle component analysis (A) before normalization and (B) after normalization are shown. Supplemental Figure S3. Diagram of each dataset’s analysis to arrive at the consensus list of 38 commonly regulated ge ...
New SigD-regulated genes identified in the
... detected in gyrA expression between the two strains. In total, six genes (appA, blsA, dhaS, spoVG, yqgA and RBAM_004640) were validated by qPCR to be SigD-regulated (Fig. 2). Three of them (spoVG, yqgA and RBAM_004640) were also confirmed by northern blot and thus described in later paragraphs. The ...
... detected in gyrA expression between the two strains. In total, six genes (appA, blsA, dhaS, spoVG, yqgA and RBAM_004640) were validated by qPCR to be SigD-regulated (Fig. 2). Three of them (spoVG, yqgA and RBAM_004640) were also confirmed by northern blot and thus described in later paragraphs. The ...
Overview of splicing relevant databases - Stamm
... Most alternative splicing databases are based on the same strategy: the exon content of transcripts is retrieved by aligning sequence of these transcripts together or against the corresponding genomic sequence. Transcript sequences are downloaded from publicly available databanks: EMBL, GenBank and ...
... Most alternative splicing databases are based on the same strategy: the exon content of transcripts is retrieved by aligning sequence of these transcripts together or against the corresponding genomic sequence. Transcript sequences are downloaded from publicly available databanks: EMBL, GenBank and ...
THE SELFISH GENE
... Culture distinguishes individuals from the other living beings. Cultural transmission is a phenomenon similar to genetic transmission because it can provoke a sort of evolution. For example, changes in clothing, customs and feeding represent forms of progress. Taken that genes are replicators, a new ...
... Culture distinguishes individuals from the other living beings. Cultural transmission is a phenomenon similar to genetic transmission because it can provoke a sort of evolution. For example, changes in clothing, customs and feeding represent forms of progress. Taken that genes are replicators, a new ...
Chapter 15 The Chromosomal Basis of Inheritance
... In humans and other mammals, there are two varieties of sex chromosomes: a larger X chromosome and a smaller Y chromosome Only the ends of the Y chromosome have regions that are homologous with corresponding regions of the X chromosome The SRY gene on the Y chromosome codes for a protein that direct ...
... In humans and other mammals, there are two varieties of sex chromosomes: a larger X chromosome and a smaller Y chromosome Only the ends of the Y chromosome have regions that are homologous with corresponding regions of the X chromosome The SRY gene on the Y chromosome codes for a protein that direct ...
Variation due to change in the individual genes
... the complicated environment of the cell protoplasm, it reacts in such a way as to convert some of the common surrounding material into an end product identical in kind with the original gene itself. This action fulfills the chemist’s definition of “autocatalysis”; it is what the physiologist would c ...
... the complicated environment of the cell protoplasm, it reacts in such a way as to convert some of the common surrounding material into an end product identical in kind with the original gene itself. This action fulfills the chemist’s definition of “autocatalysis”; it is what the physiologist would c ...
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[001-072] pierce student man
... The interference among these genes is 0.5. A fly with black body, purple eyes, and vestigial wings is crossed with a fly homozygous for gray body, red eyes, and normal wings. The female progeny are then crossed with males that have black body, purple eyes, and vestigial wings. If 1000 progeny are pr ...
... The interference among these genes is 0.5. A fly with black body, purple eyes, and vestigial wings is crossed with a fly homozygous for gray body, red eyes, and normal wings. The female progeny are then crossed with males that have black body, purple eyes, and vestigial wings. If 1000 progeny are pr ...
Gene Section IGH (Immunoglobulin Heavy) Atlas of Genetics and Cytogenetics
... IGHC genes. Eighty-two to 88 IGHV genes belong to 7 subgroups, whereas 41 pseudogenes, which are too divergent to be assigned to subgroups, have been assigned to 4 clans. Seven non-mapped IGHV genes have been described as insertion/deletion polymorphism but have not yet been precisely located. The m ...
... IGHC genes. Eighty-two to 88 IGHV genes belong to 7 subgroups, whereas 41 pseudogenes, which are too divergent to be assigned to subgroups, have been assigned to 4 clans. Seven non-mapped IGHV genes have been described as insertion/deletion polymorphism but have not yet been precisely located. The m ...
Supplemental Material For: Sex-specific Differential
... no significant differences in age or pack-years. One limitation of this approach is that this stringent matching results in a strong bias for re-sampling some of the subjects many times and others much fewer. We repeated the ensemble network analysis in the sputum gene expression dataset, building P ...
... no significant differences in age or pack-years. One limitation of this approach is that this stringent matching results in a strong bias for re-sampling some of the subjects many times and others much fewer. We repeated the ensemble network analysis in the sputum gene expression dataset, building P ...
Three Genes of the Arabidopsis RPP1 Complex
... Thomas et al., 1997). Structural comparisons between the tomato Cf-9 and Cf-4 R proteins revealed significant sequence divergence only within the N-terminal portion of their LRRs, implicating this domain in specific Avr recognition (Thomas et al., 1997). Molecular analysis of allelic variants at the ...
... Thomas et al., 1997). Structural comparisons between the tomato Cf-9 and Cf-4 R proteins revealed significant sequence divergence only within the N-terminal portion of their LRRs, implicating this domain in specific Avr recognition (Thomas et al., 1997). Molecular analysis of allelic variants at the ...
Brooker Chapter 6
... Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display ...
... Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display ...
