Table S1: Description of the cohort used for the novel - HAL
... (http://evs.gs.washington.edu/EVS/). For whole genome sequencing, we used 54 individual genomes sequenced by Complete Genomics (www.completegenomics.com). For both methods, we observed a very low sequencing coverage of SHANK1 and SHANK3 (Figure S3). Whole genome sequencing seems to be a better appro ...
... (http://evs.gs.washington.edu/EVS/). For whole genome sequencing, we used 54 individual genomes sequenced by Complete Genomics (www.completegenomics.com). For both methods, we observed a very low sequencing coverage of SHANK1 and SHANK3 (Figure S3). Whole genome sequencing seems to be a better appro ...
What I`ve done this summer
... The allelic diversity arises from unequal homologous crossing-over or gene conversions rather than point mutations. The incidence of the allelic diversity across the world appears to be characteristic of the ethnic or geographic origin of the subjects. The evolution of the three identified hot spots ...
... The allelic diversity arises from unequal homologous crossing-over or gene conversions rather than point mutations. The incidence of the allelic diversity across the world appears to be characteristic of the ethnic or geographic origin of the subjects. The evolution of the three identified hot spots ...
Section 6-3
... –Genes from one organism are transferred to the DNA of another organism • Can be done in bacteria to produce medication (insulin) • Some tomatoes have been engineered to survive cold, pests, etc – Gene therapy • splice “healthy” DNA into the DNA of a sick individual ...
... –Genes from one organism are transferred to the DNA of another organism • Can be done in bacteria to produce medication (insulin) • Some tomatoes have been engineered to survive cold, pests, etc – Gene therapy • splice “healthy” DNA into the DNA of a sick individual ...
Genética Molecular em Medicina Transfusional
... • Provides scaffold for assembly • Original strategy of Human Genome Project • Shotgun: • Quick, highly redundant – requires 7-9X coverage for sequencing reads of 500-750bp. This means that for the Human Genome of 3 billion bp, 21-27 billion bases need to be sequence to provide adequate fragment ove ...
... • Provides scaffold for assembly • Original strategy of Human Genome Project • Shotgun: • Quick, highly redundant – requires 7-9X coverage for sequencing reads of 500-750bp. This means that for the Human Genome of 3 billion bp, 21-27 billion bases need to be sequence to provide adequate fragment ove ...
Simple tandem repeats in mammalian genomes
... Caenorhabditis elegans with its more than 19,000 genes or the fruit fly Drosophila melanogaster with about 13,000 genes. This led to the assumption that the difference between humans and other organisms is not so much due the number of genes, but more to how these genes function. DNA molecules are m ...
... Caenorhabditis elegans with its more than 19,000 genes or the fruit fly Drosophila melanogaster with about 13,000 genes. This led to the assumption that the difference between humans and other organisms is not so much due the number of genes, but more to how these genes function. DNA molecules are m ...
Osman et al Supplementary Materials 1. Supplementary Materials
... using Cutadapt version 1.2.1[4]. The option “-O 3” was set, so the 3' end of any reads which matched the adapter sequence over at least 3 bp was trimmed off. The reads were further trimmed to remove low quality bases, using Sickle version 1.200 with a minimum window quality score of 20. After trimmi ...
... using Cutadapt version 1.2.1[4]. The option “-O 3” was set, so the 3' end of any reads which matched the adapter sequence over at least 3 bp was trimmed off. The reads were further trimmed to remove low quality bases, using Sickle version 1.200 with a minimum window quality score of 20. After trimmi ...
2.5.4. DNA Revision Qs
... 3 Say if the following variations are inherited or acquired. (a) freckles _____________________________________ (b) the production of an enzyme _____________________________________ (c) the ability to play a musical instrument _____________________________________ (d) the ability to form a blood clo ...
... 3 Say if the following variations are inherited or acquired. (a) freckles _____________________________________ (b) the production of an enzyme _____________________________________ (c) the ability to play a musical instrument _____________________________________ (d) the ability to form a blood clo ...
The Genetics of Alternating Hemiplegia of Childhood A long
... Sent via ISB to Complete Genomics, Inc Provides sequenced data and variant reports ...
... Sent via ISB to Complete Genomics, Inc Provides sequenced data and variant reports ...
Rosa blanda
... The objective of this project was to determine the genus, and if possible the species, of several berry-bearing trees growing in the Peconic River System by properly barcoding the leaves and berries and and compare the results using the DNA Subway website and the NCBI BLAST tool . Out of the 17 samp ...
... The objective of this project was to determine the genus, and if possible the species, of several berry-bearing trees growing in the Peconic River System by properly barcoding the leaves and berries and and compare the results using the DNA Subway website and the NCBI BLAST tool . Out of the 17 samp ...
Sequencing
... • ESTs are short sequences of 300-500 bp and represent actually expressed genes. • These are markers that are helpful in locating (map) genes on chromosomes • EST submissions therefore include both sequence and mapping information ...
... • ESTs are short sequences of 300-500 bp and represent actually expressed genes. • These are markers that are helpful in locating (map) genes on chromosomes • EST submissions therefore include both sequence and mapping information ...
The Yale Center for Genome Analysis
... than a decade of research, a $3 billion investment, and the work of 900 DNA sequencing machines in laboratories around the world. Today, the Yale Center for Genome Analysis produces the equivalent of more than 3,000 complete human genomes a month, yielding a tremendous volume of information that dri ...
... than a decade of research, a $3 billion investment, and the work of 900 DNA sequencing machines in laboratories around the world. Today, the Yale Center for Genome Analysis produces the equivalent of more than 3,000 complete human genomes a month, yielding a tremendous volume of information that dri ...
PERSONAL GENOMICS
... “They fully sequenced the genes of both his cancer cells and healthy cells for comparison, and at the same time analyzed his RNA, a close chemical cousin to DNA, for clues to what his genes were doing.” “And they found a culprit - a normal gene that was in overdrive, churning out huge amounts of a p ...
... “They fully sequenced the genes of both his cancer cells and healthy cells for comparison, and at the same time analyzed his RNA, a close chemical cousin to DNA, for clues to what his genes were doing.” “And they found a culprit - a normal gene that was in overdrive, churning out huge amounts of a p ...
Complementary DNA Sequencing: Expressed Sequence Tags and
... sequencing by matching ESTs with human sequences in GenBank. • NIH genetic sequence database, providing a collection of DNA sequences to the public. • Avg accuracy rate: 97.7% for 150 - 400 bases, having < 3% ambiguous base calls. • 348 ESTs met this criteria and were submitted to GenBank. ...
... sequencing by matching ESTs with human sequences in GenBank. • NIH genetic sequence database, providing a collection of DNA sequences to the public. • Avg accuracy rate: 97.7% for 150 - 400 bases, having < 3% ambiguous base calls. • 348 ESTs met this criteria and were submitted to GenBank. ...
Supplementary experimental procedures
... 2009 dataset, nucleotide reads for each of the RBB hits were manually annotated in order to find ...
... 2009 dataset, nucleotide reads for each of the RBB hits were manually annotated in order to find ...
DNA Technology
... • A way to identify an individual based on their unique sequences of DNA • Many sequences are the same in humans • Look for regions with greatest diversity ...
... • A way to identify an individual based on their unique sequences of DNA • Many sequences are the same in humans • Look for regions with greatest diversity ...
Cracking the code of life
... 10. Would you be willing to take a test to tell you if your children would be at risk for certain disorders and diseases? Why or why not? ...
... 10. Would you be willing to take a test to tell you if your children would be at risk for certain disorders and diseases? Why or why not? ...
On bioinformatics
... 3D protein structure data; population study data sets; assemblies of complete genomes; etc ...
... 3D protein structure data; population study data sets; assemblies of complete genomes; etc ...
Gen677_Week5a_HGT_2012
... * Poorly characterized genes * Orphan genes (no homology to any known gene) * More mobile elements, phage sequences, repeats ...
... * Poorly characterized genes * Orphan genes (no homology to any known gene) * More mobile elements, phage sequences, repeats ...
Chorionic Gonadotropin (CG) 태반성 성선자극호르몬
... Primates and an Evolutionary History of Selection Glenn A. Maston & Maryellen Ruvolo Department of Anthropology, Harvard University, Cambridge, Massachusetts Abstract ...
... Primates and an Evolutionary History of Selection Glenn A. Maston & Maryellen Ruvolo Department of Anthropology, Harvard University, Cambridge, Massachusetts Abstract ...
Incorporating Research into a Laboratory Course
... • Students learn that science often requires repetitive use of a technique to answer different questions. ...
... • Students learn that science often requires repetitive use of a technique to answer different questions. ...
Biotechnology Key Terms and Concepts
... *Refer to textbook for more detail I. Biotechnology A. Definition-use of organisms to perform practical tasks for humans B. Much of biotechnology deals with analyzing and manipulating genomes of organisms at the molecular level (DNA technology) C. Genome-complete set of an organism’s genetic materia ...
... *Refer to textbook for more detail I. Biotechnology A. Definition-use of organisms to perform practical tasks for humans B. Much of biotechnology deals with analyzing and manipulating genomes of organisms at the molecular level (DNA technology) C. Genome-complete set of an organism’s genetic materia ...
Gen660_Week4a_HGT_2014
... Grey = sequence homology around 4 genomic islands (2 related to pathogenicity and 2 related to environmental responses); black = Genomic Islands ...
... Grey = sequence homology around 4 genomic islands (2 related to pathogenicity and 2 related to environmental responses); black = Genomic Islands ...
Metagenomics
Metagenomics is the study of genetic material recovered directly from environmental samples. The broad field may also be referred to as environmental genomics, ecogenomics or community genomics. While traditional microbiology and microbial genome sequencing and genomics rely upon cultivated clonal cultures, early environmental gene sequencing cloned specific genes (often the 16S rRNA gene) to produce a profile of diversity in a natural sample. Such work revealed that the vast majority of microbial biodiversity had been missed by cultivation-based methods. Recent studies use either ""shotgun"" or PCR directed sequencing to get largely unbiased samples of all genes from all the members of the sampled communities. Because of its ability to reveal the previously hidden diversity of microscopic life, metagenomics offers a powerful lens for viewing the microbial world that has the potential to revolutionize understanding of the entire living world. As the price of DNA sequencing continues to fall, metagenomics now allows microbial ecology to be investigated at a much greater scale and detail than before.