physical maps
... Males have twofold higher mutation rate than females. Human races have very few unique distinguishing genes. All living organisms evolve from a common ancestor. Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display ...
... Males have twofold higher mutation rate than females. Human races have very few unique distinguishing genes. All living organisms evolve from a common ancestor. Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display ...
Supplementary material
... Close to 1,000 of the clones find multiple potential genes with our method. This often is a result of ESTs for the same clone belonging to different Unigene clusters, and can also be the result of closely related genes being found with the Blast method. In some cases, this automated method may not c ...
... Close to 1,000 of the clones find multiple potential genes with our method. This often is a result of ESTs for the same clone belonging to different Unigene clusters, and can also be the result of closely related genes being found with the Blast method. In some cases, this automated method may not c ...
gene technology extra qs with mark scheme
... drug which then kills the cell. Professor Stratford and his colleagues at Manchester are taking advantage of the fact that the P450 reductase gene is only switched on in an environment which is low in oxygen. His team have constructed the piece of DNA which is shown in the diagram. Region of DNA whi ...
... drug which then kills the cell. Professor Stratford and his colleagues at Manchester are taking advantage of the fact that the P450 reductase gene is only switched on in an environment which is low in oxygen. His team have constructed the piece of DNA which is shown in the diagram. Region of DNA whi ...
pplacer: linear time maximum-likelihood and Bayesian phylogenetic
... method for unknown sequences. However, traditional likelihood-based phylogenetic methods cannot be applied to large volumes of short reads from next-generation sequencing due to computational complexity issues and lack of phylogenetic signal. “Phylogenetic placement,” where a reference tree is fixed ...
... method for unknown sequences. However, traditional likelihood-based phylogenetic methods cannot be applied to large volumes of short reads from next-generation sequencing due to computational complexity issues and lack of phylogenetic signal. “Phylogenetic placement,” where a reference tree is fixed ...
Integrating Functional Genomic Information into the Saccharomyces Genome Database.
... Information about a gene’s standard name and aliases along with gene product and phenotype descriptions will continue to be displayed on SGD’s new locus page. A controlled vocabulary to describe mutant phenotypes is being developed to facilitate quick and accurate searches for genes with similar phe ...
... Information about a gene’s standard name and aliases along with gene product and phenotype descriptions will continue to be displayed on SGD’s new locus page. A controlled vocabulary to describe mutant phenotypes is being developed to facilitate quick and accurate searches for genes with similar phe ...
An rpoB signature sequence provides unique resolution for the
... The use of morphological characters for the classification of cyanobacteria has often led to ambiguous strain assignment. In the past two decades, the availability of sequences, such as those of the 16S rRNA, nif, cpc and rpoC1 genes, and the use of metagenomics, has steadily increased and has made ...
... The use of morphological characters for the classification of cyanobacteria has often led to ambiguous strain assignment. In the past two decades, the availability of sequences, such as those of the 16S rRNA, nif, cpc and rpoC1 genes, and the use of metagenomics, has steadily increased and has made ...
Recombinant DNA cloning technology
... • Antibodies can be (in theory, at least) be produced which react with any molecule. • If a protein is injected into a rabbit (or goat, or sheep, etc.) the blood isolated from the injected animal will have antibodies against the injected protein. • Mono-clonal antibodies are produced from cells grow ...
... • Antibodies can be (in theory, at least) be produced which react with any molecule. • If a protein is injected into a rabbit (or goat, or sheep, etc.) the blood isolated from the injected animal will have antibodies against the injected protein. • Mono-clonal antibodies are produced from cells grow ...
DNA Shape Dominates Sequence Affinity in Nucleosome Formation
... are arranged as c2 > c3 > c1, consistent with their relative affinities for nucleosome formation. This trend is also apparent in d1, d2, and d3, which progressively purge TA motifs (Fig. S6 [22]). Why, then, do specific sequence motifs enhance the orientational preference? We address this question b ...
... are arranged as c2 > c3 > c1, consistent with their relative affinities for nucleosome formation. This trend is also apparent in d1, d2, and d3, which progressively purge TA motifs (Fig. S6 [22]). Why, then, do specific sequence motifs enhance the orientational preference? We address this question b ...
Journal of Microbiological Methods
... Type strains with known peptidase genes and proteolytic bacteria from a grassland rhizosphere soil, a garden soil and an arable field were investigated for their genotypic proteolytic potential. For 52 out of 53 proteolytic bacterial isolates, at least one of the three peptidase classes could be ide ...
... Type strains with known peptidase genes and proteolytic bacteria from a grassland rhizosphere soil, a garden soil and an arable field were investigated for their genotypic proteolytic potential. For 52 out of 53 proteolytic bacterial isolates, at least one of the three peptidase classes could be ide ...
The Trouble with Sliding Windows and the Selective Pressure in
... To examine whether the patterns of Figure 1 are statistically significant and may thus reflect real biological processes, we apply the sliding-window analysis to data sets simulated under model M0 (one-ratio), which assumes the same dS, dN, and v across the whole sequence and independent evolution a ...
... To examine whether the patterns of Figure 1 are statistically significant and may thus reflect real biological processes, we apply the sliding-window analysis to data sets simulated under model M0 (one-ratio), which assumes the same dS, dN, and v across the whole sequence and independent evolution a ...
Quantitating Maxwell® Extracted DNA Samples Using the
... is important to know the exact amount of input DNA, so adding an accurate DNA quantitation step prior to downstream analysis is desirable. ...
... is important to know the exact amount of input DNA, so adding an accurate DNA quantitation step prior to downstream analysis is desirable. ...
PowerPoint
... SNP risk allele with large odds ratio or explains a lot of trait variance This is unknown at beginning of study • Risk SNP is common This is unknown at beginning of study Calculate power for a range of common MAFs (5-45%) • Genotype the risk SNP directly Risk SNP is unknown at beginning of study Rem ...
... SNP risk allele with large odds ratio or explains a lot of trait variance This is unknown at beginning of study • Risk SNP is common This is unknown at beginning of study Calculate power for a range of common MAFs (5-45%) • Genotype the risk SNP directly Risk SNP is unknown at beginning of study Rem ...
view PDF
... formosanus, clone BCf6-17 (GenBank accession no. AB062833). With recognized organisms, strain TI-1T was found to share greatest similarity with members of the genus Enterococcus (i.e. 92?8 % with Enterococcus saccharolyticus, 92?5 % with Enterococcus gallinarum, 92?2 % with Enterococcus hirae and 92 ...
... formosanus, clone BCf6-17 (GenBank accession no. AB062833). With recognized organisms, strain TI-1T was found to share greatest similarity with members of the genus Enterococcus (i.e. 92?8 % with Enterococcus saccharolyticus, 92?5 % with Enterococcus gallinarum, 92?2 % with Enterococcus hirae and 92 ...
cooked meat chiller treatment
... activity in cattle against potential pathogens such as E. coli O157:H7, Salmonella spp. and Staphylococcus aureus. DFMs are a feed supplement composed of living microorganisms, like probiotics. This review covers the challenges for development of DFMs that are effective over a wide range of ruminant ...
... activity in cattle against potential pathogens such as E. coli O157:H7, Salmonella spp. and Staphylococcus aureus. DFMs are a feed supplement composed of living microorganisms, like probiotics. This review covers the challenges for development of DFMs that are effective over a wide range of ruminant ...
Lesson 2 - Laboratory of Molecular Modelling
... 2. Required for evolutionary studies (e.g., tree reconstruction). 3. To detect conservation (e.g., a tyrosine that is evolutionary conserved is more likely to be a phosphorylation site). ...
... 2. Required for evolutionary studies (e.g., tree reconstruction). 3. To detect conservation (e.g., a tyrosine that is evolutionary conserved is more likely to be a phosphorylation site). ...
Honours project list
... Epidemiology and pathogenesis of Campylobacter concisus Campylobacter infections caused by C. jejuni and C. coli are of the most common causes of gastroenteritis worldwide. However, new emerging Campylobacter spp., such as C. concisus, are associated with gastroenteritis cases in children, the elder ...
... Epidemiology and pathogenesis of Campylobacter concisus Campylobacter infections caused by C. jejuni and C. coli are of the most common causes of gastroenteritis worldwide. However, new emerging Campylobacter spp., such as C. concisus, are associated with gastroenteritis cases in children, the elder ...
Catalogue of Activities Work Product – Mendelian Genetic Disorders
... In doing so, the Human Variome Project takes on four roles: 1) establishing and maintaining the standards, systems and infrastructure necessary for the worldwide collection, curation, interpretation and sharing of information across the genome; 2) advocating and promoting ethical behaviour in the fi ...
... In doing so, the Human Variome Project takes on four roles: 1) establishing and maintaining the standards, systems and infrastructure necessary for the worldwide collection, curation, interpretation and sharing of information across the genome; 2) advocating and promoting ethical behaviour in the fi ...
subunit gene. - Radboud Repository
... cells using a sense primer corresponding to nucleotide positions 1 to 20 of EST HS61279 (Accession No. R13612) and an antisense primer corresponding to nu cleotides from the most extreme 5' end of our cDNA clones. A PCR product of approximately 300 bp was subcloned and sequenced, showing that there ...
... cells using a sense primer corresponding to nucleotide positions 1 to 20 of EST HS61279 (Accession No. R13612) and an antisense primer corresponding to nu cleotides from the most extreme 5' end of our cDNA clones. A PCR product of approximately 300 bp was subcloned and sequenced, showing that there ...
Title Heterochromatin Blocks Constituting the Entire
... repeats of the largest scale were four 17-bp blocks containing up to two mismatched nucleotides (Fig. 5A). These repeats spanned about half of the consensus sequence. With respect to inverted repeats, several pairs of blocks were found scattered throughout the consensus sequence (Fig. 5B). Of the 14 ...
... repeats of the largest scale were four 17-bp blocks containing up to two mismatched nucleotides (Fig. 5A). These repeats spanned about half of the consensus sequence. With respect to inverted repeats, several pairs of blocks were found scattered throughout the consensus sequence (Fig. 5B). Of the 14 ...
Molecular biology of Ri-plasmid—A review
... al., 1986). Mutations in rolA (rolA–) results in the formation of long, straight roots giving the tumor a less compact appearance on Kalanchoe diagremontiana leaves (figure 2). The rolB mutation eliminates both callus or root formation at the wound site, while rolC– and rolD–mutations are more subtl ...
... al., 1986). Mutations in rolA (rolA–) results in the formation of long, straight roots giving the tumor a less compact appearance on Kalanchoe diagremontiana leaves (figure 2). The rolB mutation eliminates both callus or root formation at the wound site, while rolC– and rolD–mutations are more subtl ...
lecture 3
... - found in telomeric regions - used in original DNA fingerprinting technique by Alec Jeffreys ...
... - found in telomeric regions - used in original DNA fingerprinting technique by Alec Jeffreys ...
Sequences of flavivirus-related RNA viruses persist in DNA form
... an artefact resulting from the manipulation of mosquito cell lines, since they exist under natural conditions. This finding has major implications regarding evolution, as it represents an entirely different mechanism by which genetic diversity may be generated in eukaryotic cells distinct from accep ...
... an artefact resulting from the manipulation of mosquito cell lines, since they exist under natural conditions. This finding has major implications regarding evolution, as it represents an entirely different mechanism by which genetic diversity may be generated in eukaryotic cells distinct from accep ...
primer on genetic epidemiology
... the assumption of identical environment in twin studies may be difficult to hold. Twins may display difference in delivery process, special life events, and interactions with teachers or friends. In an alternative adoption study, a biological parent and an adopted-away offspring, or a full sibling a ...
... the assumption of identical environment in twin studies may be difficult to hold. Twins may display difference in delivery process, special life events, and interactions with teachers or friends. In an alternative adoption study, a biological parent and an adopted-away offspring, or a full sibling a ...
Super models
... other systems. S. cerevisiae boasts the awesome power of yeast genetics. Drosophila claims sophisticated genetics, polytene chromosomes, and a wealth of information on developmental biology. A rapid generation time, limited number of cells, and hermaphroditism distinguish C. elegans. External fertil ...
... other systems. S. cerevisiae boasts the awesome power of yeast genetics. Drosophila claims sophisticated genetics, polytene chromosomes, and a wealth of information on developmental biology. A rapid generation time, limited number of cells, and hermaphroditism distinguish C. elegans. External fertil ...
Metagenomics
Metagenomics is the study of genetic material recovered directly from environmental samples. The broad field may also be referred to as environmental genomics, ecogenomics or community genomics. While traditional microbiology and microbial genome sequencing and genomics rely upon cultivated clonal cultures, early environmental gene sequencing cloned specific genes (often the 16S rRNA gene) to produce a profile of diversity in a natural sample. Such work revealed that the vast majority of microbial biodiversity had been missed by cultivation-based methods. Recent studies use either ""shotgun"" or PCR directed sequencing to get largely unbiased samples of all genes from all the members of the sampled communities. Because of its ability to reveal the previously hidden diversity of microscopic life, metagenomics offers a powerful lens for viewing the microbial world that has the potential to revolutionize understanding of the entire living world. As the price of DNA sequencing continues to fall, metagenomics now allows microbial ecology to be investigated at a much greater scale and detail than before.