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a copy of the Sample Syllabus
a copy of the Sample Syllabus

... Objectives: The fast pace of modern molecular genetics research is driven by major challenges in medicine, agriculture, and industry; and, ultimately, by intellectual curiosity. There is intense public interest in the human genome project and genetic engineering, due in part to fascination with how ...
Advances in Genetics
Advances in Genetics

What is the genomic location for the rice blast resistance gene Pi-ta
What is the genomic location for the rice blast resistance gene Pi-ta

... Answer: The nearest marker to Pi-ta is C53024S. Note that there are two sequence accessions that have been associated with the marker. This is because RFLP clones generally have both forward and reverse sequence. (Occasionally there are additional sequences associated with a given marker.) You can a ...
Molecular Genetics
Molecular Genetics

... of genes and chromosomes in individuals from generation to generation. Molecular Genetics: focuses on the structure and function of genes at the molecular level. Evolutionary genetics: focus on the study of genetic basis of changes in organism over time  Population Genetics: focuses on heredity i ...
Genetically Engineering Plants
Genetically Engineering Plants

... nucleotides encodes all of the cell's information. • A set of nucleotides that code for a particular protein is called a gene, and each chromosome contains thousands of genes. Since the proteins a cell produces are responsible for its specific traits, by changing the genes of an organism you can cha ...
Standard Grade Biology – Investigating Cells
Standard Grade Biology – Investigating Cells

... Proteins are made up of a large number of sub-units called amino acids (there are about 20 amino acids). These are joined together into polypeptide chains consisting of hundreds of amino acids linked together. The sequence of the amino acids will determine the final structure of the protein and the ...
Biology 303 EXAM II 3/14/00 NAME
Biology 303 EXAM II 3/14/00 NAME

... sure to fill-out your student number and name on the answer sheet. Also, write “version 1” in the space for “college.” Good luck! ...
Timeline Code DNAi Site Guide
Timeline Code DNAi Site Guide

... Click on a "spot" to find out about the gene or genes at that location ...
APBioTech 2015 16
APBioTech 2015 16

... A stem cell is a relatively unspecialized cell that can reproduce itself indefinitely and differentiate into specialized cells of one or more types ...
38. Bacterial Transformation Simulation Lesson Plan
38. Bacterial Transformation Simulation Lesson Plan

Sickle Cell Anemia
Sickle Cell Anemia

... – view protein structure Scott - What is a genetic disorder? Example of genetic disorder - Sickle Cell – Map of where disease is prevalent What causes the genetic disorder? Why does it persist? When did it originate? Scott - INTERACTIVE – 30 minutes Where is HB gene? NCBI - Human genome -use ncbi to ...
lizcar~1
lizcar~1

... generation of successful transgenics ...
Extra Homework problems
Extra Homework problems

Three Revolutions in Molecular Biology - Pittsburgh
Three Revolutions in Molecular Biology - Pittsburgh

... The roles of microRNAs and other small RNAs that associate with factors in the microRNA pathway in gene regulation and cancer will be discussed. Long non-coding RNAs in mammals are products of a permissive transcription of the genome, many associated with transcriptional enhancers and divergent tran ...
下載 - 國立高雄師範大學
下載 - 國立高雄師範大學

... (B) They are used to communicate between different organisms (C) They elicit specific biological responses from target cells (D) They are produced by endocrine glands (E) They are modified amino acids, peptides, or steroid molecules 6. Frequently, very few molecules of a hormone are required to affe ...
Chapter 12: Genetics and Health
Chapter 12: Genetics and Health

Lecture#31 – Evolution and cis
Lecture#31 – Evolution and cis

... Changes DNA sequence -> changes in physical traits Research has focused on genes for last ~40 years –> amino acid coding sequences Human – Drosophila comparison Drosophila ~14K genes -> human ~35K genes ~2x change in total number, but humans are much more complex Human – Chimp comparison -> 99% same ...
1 Molecular Genetics
1 Molecular Genetics

... the first draft of the sequence of the human human genome ...
4.2 Mutation
4.2 Mutation

Bioinformatics: One Minute and One Hour at a Time
Bioinformatics: One Minute and One Hour at a Time

... Hierarchical Clustering • Join two most similar genes • Join next two most similar “objects” (genes or clusters of genes) • Distance from one gene to a set of genes is minimum of all distances from the gene to the individual members ...
Genetics Vocabulary Note-Taking Chart
Genetics Vocabulary Note-Taking Chart

... Chromosomes, Compact spools of DNA in a cell’s nucleus n. that carry the code for the organism’s inherited characteristics DNA, n. The genetic molecule in a cell’s nucleus that determines the organism’s genetic traits Gene, n. A segment of DNA on a chromosome that determines a particular inherited G ...
semester 1 review
semester 1 review

... 34. Write out the equation for cellular respiration. Indicate the products and reactants. 35. Identify the steps in cellular respiration in the proper sequence. For each indicate where it occurs (be specific). Indicate the products of each step (include the electron carriers) 36. How are cellular r ...
Gene Cloning and Karyotyping
Gene Cloning and Karyotyping

... • One goal may be to produce a protein product for use. • A second goal may be to prepare many copies of the gene itself. – This may enable scientists to determine the gene’s nucleotide sequence or provide an organism with a new metabolic capability by transferring a gene from another organism. ...
Manipulating genes and cells (Kap. 10)
Manipulating genes and cells (Kap. 10)

... ¾ nucleic acid hybridization techniques ¾ genomic and cDNA libraries ¾ cloning of DNA ¾ PCR and PCR applications ¾ isolating cells and growing them in culture ¾ protein expression in recombinant cell lines ¾ genetically altered animals and plants ...
What is another name for a polypeptide?
What is another name for a polypeptide?

... Other mutations are caused by mutagens (MYEW tuh junz), which are chemicals or radiation that can damage DNA. Chemical mutagens are being studied for possible use in treating HIV—the virus that ...
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Genome editing

Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, replaced, or removed from a genome using artificially engineered nucleases, or ""molecular scissors."" The nucleases create specific double-stranded break (DSBs) at desired locations in the genome, and harness the cell’s endogenous mechanisms to repair the induced break by natural processes of homologous recombination (HR) and nonhomologous end-joining (NHEJ). There are currently four families of engineered nucleases being used: Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), the CRISPR/Cas system, and engineered meganuclease re-engineered homing endonucleases.It is commonly practiced in genetic analysis that in order to understand the function of a gene or a protein function one interferes with it in a sequence-specific way and monitors its effects on the organism. However, in some organisms it is difficult or impossible to perform site-specific mutagenesis, and therefore more indirect methods have to be used, such as silencing the gene of interest by short RNA interference (siRNA) . Yet gene disruption by siRNA can be variable and incomplete. Genome editing with nucleases such as ZFN is different from siRNA in that the engineered nuclease is able to modify DNA-binding specificity and therefore can in principle cut any targeted position in the genome, and introduce modification of the endogenous sequences for genes that are impossible to specifically target by conventional RNAi. Furthermore, the specificity of ZFNs and TALENs are enhanced as two ZFNs are required in the recognition of their portion of the target and subsequently direct to the neighboring sequences.It was chosen by Nature Methods as the 2011 Method of the Year.
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