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Basic Genetics Notes
Basic Genetics Notes

... • Get ½ of DNA from your mom • The other ½ of DNA comes from your dad ...
Genetics of prokaryotic cell
Genetics of prokaryotic cell

...  with classical Mendelian inheritance  with non-Mendelian inheritance - imprinting errors - dynamic mutations - uniparental disomy ...
Genetics of prokaryotic cell
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What Would You Do? - Honors 210G (Section 01): Ebola
What Would You Do? - Honors 210G (Section 01): Ebola

... shared must be accurate, says Ellen the whole genome; you’re going to Wright Clayton, who studies law see Y and Z.” and genetics at Vanderbilt UniverWhile many genetic studies strip sity in Nashville, and they should be DNA samples of personal identifiuseful. But “deciding your threshers and assign e ...
MI Practice EOC/Final Exam - Kenwood Academy High School
MI Practice EOC/Final Exam - Kenwood Academy High School

... B. Go to all practices, games, and conditioning training, as well as doing extra workouts with his brother every day until the day of the tournament. C. Attend conditioning training and practices, stretch before any physical activity, eat a healthy and balanced diet and wear his orthopedic cleats wh ...
Chapter 13
Chapter 13

... 20. If the sequence TCGTA was used as a template in DNA replication, what would the sequence of bases be on the newly synthesized strand? A) ATGCT B) CTACG C) AGCAT D) GCATC E) TCGTA ...
Gene Duplication and Gene Families
Gene Duplication and Gene Families

... freed from the constraints of natural selection and allowed to accumulate mutational changes without phenotypic effect. They may evolve modified, or more rarely, completely different functions. Even when genes in a family have similar functions they may be expressed in different tissues and at diffe ...
Powerpoint template for scientific posters (Swarthmore
Powerpoint template for scientific posters (Swarthmore

... The “Adopt-a-Genome” Education Program sponsored by the DOE Joint Genome Institute makes available to colleges/universities microbial genome sequence data for use in authentic research in genome annotation. Genome annotation identifies and attaches biological information to putative genes using bioi ...
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chromosomal

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Chap 7 Photosynthesis

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... http://www.sanger.ac.uk/HGP/havana/ ...
Gene Regulation in Cells
Gene Regulation in Cells

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HW#2 (first draft)

... Several single colonies can be screened after transformation for correct product. Reasonable if correct product is only one in ten or so. ...
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Exam Procedures: this isBMB 526 Exam #1 11/5/12 this is form A

... Questions 28 and 29 refer to two patients in a Case Study, designated as Case A. 28. A 2-day-old boy exhibits extreme lethargy and hyperventilation. Complete blood count (CBC) report documented megaloblastic anemia (low hematocrit, low RBC count, low plasma hemoglobin, and elevated mean corpuscular ...
Powerpoint - University of British Columbia
Powerpoint - University of British Columbia

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NAME: NWAIWU ROSEMARY DEPT: BIOCHEMISTRY COURSE
NAME: NWAIWU ROSEMARY DEPT: BIOCHEMISTRY COURSE

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... presence of recognition sites does not necessarily interfere with our method, although additional fitness tests might be necessary. An increased specificity could be achieved by using alternative endonucleases, such as artificial zinc-finger nucleases [35,36]. Careful endonuclease selection is thus ...
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Powerpoint - Wishart Research Group

... • Most gene finders don’t handle overlapping or nested genes • Most can’t find non-protein genes (tRNAs) ...
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1) Lecture notes: effects of bile salts on cholesterol metabolism

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... years ago most CF patients died as babies. Now most in the United States live into their late 30s. The Cystic Fibrosis Gene To find the CF gene, geneticists looked for markers (fragments of identifiable DNA) on specific chromosomes by comparing the DNA of CF-affected individuals to DNA of people wit ...
Biology 303 EXAM II 3/14/00 NAME
Biology 303 EXAM II 3/14/00 NAME

... 10. Chromosomal inversions can bring about phenotypic changes. This is best explained by the phenomenon known as: 1. polyploidy. 2. genetic deletion. 3. position effect. 4. aneuploidy. ...
Biology 303 EXAM II 3/14/00 NAME
Biology 303 EXAM II 3/14/00 NAME

... 10. Chromosomal inversions can bring about phenotypic changes. This is best explained by the phenomenon known as: 1. polyploidy. 2. genetic deletion. 3. position effect. 4. aneuploidy. ...
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... In some plants, when the soil pH is >7 blue flowers are produced and when the soil pH is <7 pink flowers are produced. It’s the best explanation for the color changes in these plants. A – Multiple alleles determine the color of the flowers. B – The change in flower color is the result of a mutation. ...
CRISPR Applications: Mouse - Innovative Genomics Institute
CRISPR Applications: Mouse - Innovative Genomics Institute

... More reliable sgRNA design (particularly for desirable HDR editing) Complex genome editing still requires ESCs Precise genotyping in mouse embryos Somatic mouse models Rapid, easy, tissue specific, inducible, multiplex genome editing. Delivery of Cas9 for building somatic mouse models. (improved vir ...
Potatoes à la Genetic Carte - Max-Planck
Potatoes à la Genetic Carte - Max-Planck

... Although most of these mutations have no effect, some can trigger negative consequences while others promote positive characteristics. It is the search for the latter that is keeping people busy in Cologne. However, in view of the one billion base pairs and approximately 30,000 genes that exist in t ...
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Genome editing

Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, replaced, or removed from a genome using artificially engineered nucleases, or ""molecular scissors."" The nucleases create specific double-stranded break (DSBs) at desired locations in the genome, and harness the cell’s endogenous mechanisms to repair the induced break by natural processes of homologous recombination (HR) and nonhomologous end-joining (NHEJ). There are currently four families of engineered nucleases being used: Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), the CRISPR/Cas system, and engineered meganuclease re-engineered homing endonucleases.It is commonly practiced in genetic analysis that in order to understand the function of a gene or a protein function one interferes with it in a sequence-specific way and monitors its effects on the organism. However, in some organisms it is difficult or impossible to perform site-specific mutagenesis, and therefore more indirect methods have to be used, such as silencing the gene of interest by short RNA interference (siRNA) . Yet gene disruption by siRNA can be variable and incomplete. Genome editing with nucleases such as ZFN is different from siRNA in that the engineered nuclease is able to modify DNA-binding specificity and therefore can in principle cut any targeted position in the genome, and introduce modification of the endogenous sequences for genes that are impossible to specifically target by conventional RNAi. Furthermore, the specificity of ZFNs and TALENs are enhanced as two ZFNs are required in the recognition of their portion of the target and subsequently direct to the neighboring sequences.It was chosen by Nature Methods as the 2011 Method of the Year.
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