• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Fast and Flexible Single Nucleotide Polymorphism (SNP) Detection
Fast and Flexible Single Nucleotide Polymorphism (SNP) Detection

... which pedigree analysis track transmission of a disease through a family, have been successfully applied to in the detection of Mendelian disorders. In recent years a more powerful approach involving the detection of single nucleotide polymorphisms (SNPs) has become increasingly popular. By conventi ...
File - MS Barnes` Biology 12
File - MS Barnes` Biology 12

... Do questions #8 & 9 from your textbook below. #8 A food dye that has been identified as a chemical mutagen poses greater dangers for a developing fetus than for an adult. A fetus is undergoing rapid developmental growth within the uterus. The rate of mitosis for all cells is much faster than that wi ...
DNA chips
DNA chips

... Readout using micro-flow cells or optic fiber arrays ...
DNA and Genetics
DNA and Genetics

... structure and replication. Simple DNA extraction could be performed as an introduction to the Unit. The stages of the cell cycle should then be covered. In the teaching of the cell cycle, the importance of the varying levels of CdKs at various points should be emphasised. The significance of the dif ...
Candidate gene screening using long-read sequencing
Candidate gene screening using long-read sequencing

... PacBio, Menlo Park, CA USA ...
Study questions - Pre-lab
Study questions - Pre-lab

... C.R. Noller. One night in his lab Fox accidentally over-poured PTC and complained of the 2. bitter taste in the air as the powder diffused around him. His colleague Noller, on the other hand, tasted 3. nothing. Intrigued by the vast differences in their tasting Fox and Noller went on to explore the ...
Learning Log/ FRQ-style Question
Learning Log/ FRQ-style Question

... Describe an environmental factor that would cause a change in gene expression, and the affect that it would have on an organism. Many bacteria respond to an environment with and without the presence of lactose. If lactose is present in the environment, a genetic operon repressor is inactive, and a g ...
15.2 Recombinant DNA
15.2 Recombinant DNA

... Today, scientists can produce custom-built DNA molecules in the lab and then insert those molecules—along with the genes they carry—into living cells. Machines known as DNA synthesizers are used to produce short pieces of DNA, up to several hundred bases in length. These synthetic sequences can then ...
BI:4224
BI:4224

... 5’ direction, synthesizing a complementary RNA molecule w/ elongation occurring in the 3’ to 5’ direction. The DNA sequence dictates where RNA synthesis will occur. There are also a number of RNA-dependent RNA polymerases as well that use RNA as their template for synthesis of a new strand of RNA. F ...
Aimhigher Monitoring Template
Aimhigher Monitoring Template

... Each session offered to the schools lasted 45 -50mins. In some schools the sessions were in direct succession, in others, one was before lunch and the other after lunch. Pupils were asked their opinion on the length of the event; 74.3% thought that the event was just right in length, 16.9% thought i ...
Activity 2.2.1: Gene Therapy Introduction
Activity 2.2.1: Gene Therapy Introduction

... Gene therapy is the practice of inserting functional genes into a person’s genome to replace faulty genes. Doctors and medical researchers are working to restore function to cells that are affected by genetic disorders. To accomplish this goal, scientists have to get the right gene to the right cell ...
Prentice Hall Biology - Mid
Prentice Hall Biology - Mid

... Producing Recombinant DNA Transforming (and then Cloning Cells) Screening Target Cells with gene (Clone the screened Target cell) ...
Adaptive Radiation and Macroevolution in the Hawaiian Silverswords
Adaptive Radiation and Macroevolution in the Hawaiian Silverswords

... (photos from http://www.botany.hawaii.edu/faculty/carr/silversword.htm) ...
BioUnit3AlignedMaterialsList
BioUnit3AlignedMaterialsList

... reason for these differences in physical characteristics (called phenotype) is the different combination of genes possessed by each individual. To illustrate the tremendous variety possible when you begin to combine genes, you and a classmate will establish the genotypes for a potential offspring. Y ...
Sequences of flavivirus-related RNA viruses persist in DNA form
Sequences of flavivirus-related RNA viruses persist in DNA form

... and Aedes aegypti mosquitoes, demonstrating for the first time an integration into a eukaryotic genome of a multigenic sequence from an RNA virus that replicates without a recognized DNA intermediate. In the Aedes albopictus C6/36 cell line, an open reading frame (ORF) of 1557 aa with protease/helic ...
What is the Unit of Natural Selection?
What is the Unit of Natural Selection?

... phenotypic effects tend to out-replicate those with other phenotypic effects. If they are also germ-line replicators, these changes in relative frequency can have a long term evolutionary impact.” [3] The question now becomes one of locating the level in the hierarchy of living systems at which the ...
Significance of multiple mutations in cancer
Significance of multiple mutations in cancer

... There is increasing evidence that in eukaryotic cells, DNA undergoes continuous damage, repair and resynthesis. A homeostatic equilibrium exists in which extensive DNA damage is counterbalanced by multiple pathways for DNA repair. In normal cells, most DNA damage is repaired without error. However, ...
lecture05_11
lecture05_11

... PROBLEMS… • When searching for a motif in a genome using PSSM or other methods – the motif is usually found all over the place ->The motif is considered real if found in the vicinity of a gene. • Checking experimentally for the binding sites of a specific TF (location analysis) – the sites that bin ...
2009 Hart and Grosbe.. - Evolution and Ecology | UC Davis
2009 Hart and Grosbe.. - Evolution and Ecology | UC Davis

... should be typical of cirripedes. Alternatively, if, as I suggest, rhizocephalans are not arthropods but acquired arthropod larvae by hybrid transfer, at least three genomes should be detected. Those that code for nauplius and cypris larvae should be similar to those in cirripedes, while the third ‘a ...
Genomic Analysis of Arabidopsis Thaliana
Genomic Analysis of Arabidopsis Thaliana

... In addition to the many advantages described above, the rapid rise of Arabidopsis as a preferred plant model is based upon its small genome size and few repetitive sequences. The framework for Arabadopsis genomics was set by early kinetic analyses of total Arabidopsis DNA in 1984. Most of the genome ...
3.C.1 - The Bio Edge
3.C.1 - The Bio Edge

... LO 3.24 The student is able to predict how a change in genotype, when expressed as a phenotype, provides a variation that can be subject to natural selection. [See SP 6.4, 7.2] LO 3.25 The student can create a visual representation to illustrate how changes in a DNA nucleotide sequence can result in ...
- e-space: Manchester Metropolitan University`s
- e-space: Manchester Metropolitan University`s

... given genetic library [42]. We dissected the functional diversity of a constrained library, and found that even such relatively simple libraries can provide a rich variety of potential behaviours. As we have established, given a library of regulatory elements, it is possible to construct many circui ...
Leukaemia Section t(9;11)(p22;q23) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(9;11)(p22;q23) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... Fusion protein ...
fingerprint - West Essex Regional School District
fingerprint - West Essex Regional School District

... specific places, it will form different sized DNA fragments ◦ Using a technology called Gel Electrophoresis, these DNA fragments can be separated within a gel ◦ The results will form band patterns (or fingerprint) in the gel specific to that individual ◦ Relatives may share some bands and this is ho ...
Hypothesis for the evolutionary origin of the chloroplast ribosomal
Hypothesis for the evolutionary origin of the chloroplast ribosomal

... The amino acid sequence has been aligned with the sequences for L21 r-protein from M. polymorpha (Kochi et al. 1988) and E. coli (Heiland and Wittmann-Liebold 5979) as shown in Fig. 2. The spinach L21 r-protein contains roughly 500 residues common to all three sequences, a region which we term the c ...
< 1 ... 113 114 115 116 117 118 119 120 121 ... 445 >

Genome editing

Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, replaced, or removed from a genome using artificially engineered nucleases, or ""molecular scissors."" The nucleases create specific double-stranded break (DSBs) at desired locations in the genome, and harness the cell’s endogenous mechanisms to repair the induced break by natural processes of homologous recombination (HR) and nonhomologous end-joining (NHEJ). There are currently four families of engineered nucleases being used: Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), the CRISPR/Cas system, and engineered meganuclease re-engineered homing endonucleases.It is commonly practiced in genetic analysis that in order to understand the function of a gene or a protein function one interferes with it in a sequence-specific way and monitors its effects on the organism. However, in some organisms it is difficult or impossible to perform site-specific mutagenesis, and therefore more indirect methods have to be used, such as silencing the gene of interest by short RNA interference (siRNA) . Yet gene disruption by siRNA can be variable and incomplete. Genome editing with nucleases such as ZFN is different from siRNA in that the engineered nuclease is able to modify DNA-binding specificity and therefore can in principle cut any targeted position in the genome, and introduce modification of the endogenous sequences for genes that are impossible to specifically target by conventional RNAi. Furthermore, the specificity of ZFNs and TALENs are enhanced as two ZFNs are required in the recognition of their portion of the target and subsequently direct to the neighboring sequences.It was chosen by Nature Methods as the 2011 Method of the Year.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report