• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
AP Biology
AP Biology

...  Genes for antibiotic resistance = R Plasmids  Role in rapid evolution  Method for spreading “antibiotic resistance” ...
bio 30 ch 18 molecular genetics review
bio 30 ch 18 molecular genetics review

... 2. DNA replication copies the entire DNA code. Transcription makes a short section of the DNA. 3. DNA nucleotides include thymines, while RNA contains uracil 6. If mRNA can not be produced, proteins can not be synthesized. Functional proteins serve a variety of essential body functions and include h ...
Shotgun DNA sequencing using cloned DNase I
Shotgun DNA sequencing using cloned DNase I

... by restriction enzymes with four-base recognition sites, moreover, are shorter than the length of accurate sequence that can be read from a gel, so sequencing such fragments represents an inefficient use of resources. For the above reasons a simple method was developed for shotgun DNA sequencing usi ...
gen-305-presentation-8-16
gen-305-presentation-8-16

... • The genome comprises all the genetic material that an organism possesses – In bacteria, it is typically a single circular chromosome – In eukaryotes, it refers to one complete set of nuclear chromosomes ...
Deep Insight Section Common fragile sites and genomic instability
Deep Insight Section Common fragile sites and genomic instability

... induced by aphidicolin, an inhibitor of DNA synthesis that, by affecting DNA polymerases alpha, delta and epsilon, has been shown to activate most fragile sites (Mrasek et al., 2010), inducing gaps that are microscopically visible in metaphase chromosomes. At the molecular level, the phenomenon of c ...
NAME: ________________ DATE: ____________ BLOCK: _____
NAME: ________________ DATE: ____________ BLOCK: _____

... Bitter-tasting compounds are recognized by receptor proteins on the surface of taste cells. There are approximately 30 genes for different bitter taste receptors in mammals. The gene for the PTC taste receptor, TAS2R38, was identified in 2003. Sequencing identified three nucleotide positions that va ...
Isolation of a gene encoding a novel chloroplast protein by T
Isolation of a gene encoding a novel chloroplast protein by T

1 X chromosome crossover formation and genome stability in
1 X chromosome crossover formation and genome stability in

... The germ line efficiently combats numerous genotoxic insults to ensure the high fidelity propagation of unaltered genomic information across generations. Yet, germ cells in most metazoans also intentionally create double-strand breaks (DSBs) to promote DNA exchange between parental chromosomes, a pr ...
Consalez, GG, Stayton, CL, Freimer, NB, Goonewardena, Brown, WT, Gilliam, TC and Warren, ST: Isolation and characterization of a highly polymorphic human locus (DXS 455) in proximal Xq28. Genomics 12:710-714 (1992).
Consalez, GG, Stayton, CL, Freimer, NB, Goonewardena, Brown, WT, Gilliam, TC and Warren, ST: Isolation and characterization of a highly polymorphic human locus (DXS 455) in proximal Xq28. Genomics 12:710-714 (1992).

... lane number corresponds to the same female subject. TO map DXS455 within Xq28 more precisely, meiotic crossovers between established Xq28 marker loci were used as map indicators. As shown in Fig. 5, two families segregating fragile X syndrome that exhibited crossovers with four flanking markers were ...
RECOMBINANT DNA TECHNOLOGY: APPLICATIONS IN THE
RECOMBINANT DNA TECHNOLOGY: APPLICATIONS IN THE

... fragment length polymorphisms (RFLPs), short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs). All three can occur within genes as well as in intergenic regions, and altogether there are several million of these polymeric sites I the human genome, with SNPs being the most common. Gen ...
Document
Document

... Thus, these individuals do not play a role in the gene pool. However, sometimes the deleted DNA sequence in some individuals may trigger the editing machinery so that the machinery would insert back nucleotides to those positions of deletions and preserve the correct reading frame. In this case, the ...
Document
Document

... Li-Fraumeni syndrome Individuals in a family have a propensity to develop tumors at an early age Often these families have a deletion in the p53 gene When this family has a child, they might want to know if their child has normal p53 or not Nucleic acid hybridization provides a means to rapidly dete ...
cDNA chips
cDNA chips

... Readout using micro-flow cells or optic fiber arrays ...
mRNA Codon
mRNA Codon

... Proteins are vital to living organisms. They are involved in chemical reactions, oxygen transport, muscle contraction, sensory perception, blood clotting, and many other activities. The great variety of roles requires equal variety in the structure of protein molecules. This variety is achieved by m ...
File
File

A novel variant of the amelogenin gene (AMEL-X) in cattle
A novel variant of the amelogenin gene (AMEL-X) in cattle

... 2005] presumably due to selection pressure. The number of variations observed in AMEL-Y vs AMEL-X sequences indicate that both genes were not subjected to the same evolutionary constraints [Delgado et al. 2005]. Thus, it seems particularly important to verify whether amelogenin protein coded by the ...
2 Mendelismo
2 Mendelismo

... had been worked out. Advances in molecular genetics led to the first recombinant DNA experiments in 1973, which touched off another revolution in genetic research. Walter Gilbert (b. 1932) and Frederick Sanger (b. 1918) developed methods for sequencing DNA in 1977. The polymerase chain reaction, a t ...
Linking of the human immunoglobulin VKJKCK regions by
Linking of the human immunoglobulin VKJKCK regions by

... studies the finding of reciprocal recombination products of V R and J v flanks in lymphoid cells (13-17) led to the proposal of a sister chromatid exchange process (15,16) and to an inversion/ deletion model for V..-J., recombination (17). The latter model requires some of the V,, gene segments to b ...
Core Concepts
Core Concepts

... (carbohydrates, lipids, proteins, and nucleic acids).  B2.2D - Explain the general structure and primary functions of the major complex organic molecules that compose living organisms.  B2.2E Describe how dehydration and hydrolysis relate to organic molecules.  B2.2f - Explain the role of enzymes ...
Newly found, `thrifty` genetic variant influences
Newly found, `thrifty` genetic variant influences

... School of Public Health performed analyses using the genotype information to look for signals across Once modern conveniences like motor vehicles and the whole genome that genetic variants might be high-calorie foods became prevalent among associated with BMI. They found that one region of Samoans, ...
We conducted a full analysis on the excluded 26 cases (see details
We conducted a full analysis on the excluded 26 cases (see details

... in D. grimshawi, D. mojavensis and D. virilis. However, this may be wrong. For example, in D. grimshawi, GH14404 appears to be a best-to-best ortholog of CG13762 based on UCSC genomic alignment. GH14404 is in the Muller D element. Thus case is more likely to be a one-exon-to-multiple-exon DNA-level ...
Paris_iGEM_Presentation_-_041708
Paris_iGEM_Presentation_-_041708

... • Monitor changes in soma/germ genome & phenotype ▫ Do they swap genes? ▫ Do they become more or less dependent? ...
Exploring a fatal outbreak of Escherichia coli using
Exploring a fatal outbreak of Escherichia coli using

... Searching for specific genes in PATRIC Scientists studying the 2011 outbreak found that genomes isolated from the E. coli bacteria associated with the epidemic certain genes that had previously been associated with virulence (attA, aggR, aap, aggA, and aggC). In addition, these strains also carried ...
Identification of editing positions in the ndhB transcript from maize
Identification of editing positions in the ndhB transcript from maize

... previously for the maize chloroplast ndhA transcript and the plant mitochondrial nadl transcripts (13). The present finding of two other editing sites common to the two plant organelles adds further support to the suggestion that the editing processes in both plant organelles share common components ...
genetics
genetics

... Prometaphase: The nuclear membrane begins to disintegrate and chromosome spread around the cells. Each chromosome becomes attached at its centromere to a microtubule of the mitotic ...
< 1 ... 111 112 113 114 115 116 117 118 119 ... 445 >

Genome editing

Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, replaced, or removed from a genome using artificially engineered nucleases, or ""molecular scissors."" The nucleases create specific double-stranded break (DSBs) at desired locations in the genome, and harness the cell’s endogenous mechanisms to repair the induced break by natural processes of homologous recombination (HR) and nonhomologous end-joining (NHEJ). There are currently four families of engineered nucleases being used: Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), the CRISPR/Cas system, and engineered meganuclease re-engineered homing endonucleases.It is commonly practiced in genetic analysis that in order to understand the function of a gene or a protein function one interferes with it in a sequence-specific way and monitors its effects on the organism. However, in some organisms it is difficult or impossible to perform site-specific mutagenesis, and therefore more indirect methods have to be used, such as silencing the gene of interest by short RNA interference (siRNA) . Yet gene disruption by siRNA can be variable and incomplete. Genome editing with nucleases such as ZFN is different from siRNA in that the engineered nuclease is able to modify DNA-binding specificity and therefore can in principle cut any targeted position in the genome, and introduce modification of the endogenous sequences for genes that are impossible to specifically target by conventional RNAi. Furthermore, the specificity of ZFNs and TALENs are enhanced as two ZFNs are required in the recognition of their portion of the target and subsequently direct to the neighboring sequences.It was chosen by Nature Methods as the 2011 Method of the Year.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report