Microbial Discovery Activity - American Society for Microbiology
... After everyone replicates and translates their sequence, have the students report out the results of their translation (the amino acid sequence) on the board in the same order that the sequences were received. See Figures 1A, B, C, and D in the Appendix for a representative sample of the results fro ...
... After everyone replicates and translates their sequence, have the students report out the results of their translation (the amino acid sequence) on the board in the same order that the sequences were received. See Figures 1A, B, C, and D in the Appendix for a representative sample of the results fro ...
biopatt - Carnegie Mellon School of Computer Science
... Pfam is a large collection of protein multiple sequence alignments and profile hidden Markov models. Pfam is available on the World Wide Web in the UK,…, Sweden, …, France, …, US. The latest version (6.6) of Pfam contains 3071 families, which match 69% of proteins in SWISS-PROT 39 and TrEMBL 14. Str ...
... Pfam is a large collection of protein multiple sequence alignments and profile hidden Markov models. Pfam is available on the World Wide Web in the UK,…, Sweden, …, France, …, US. The latest version (6.6) of Pfam contains 3071 families, which match 69% of proteins in SWISS-PROT 39 and TrEMBL 14. Str ...
—1— User Guide © Copyright 2009 Robert C. Edgar, all rights
... Evolver explicitly models protein evolution. The CDS of a gene must begin with a start codon and must contain exactly one stop codon which is the last codon in the CDS. Rare anomalies such as in-frame stop codons are thus not modeled. Frame is maintained: the CDS length must always be a multiple of ...
... Evolver explicitly models protein evolution. The CDS of a gene must begin with a start codon and must contain exactly one stop codon which is the last codon in the CDS. Rare anomalies such as in-frame stop codons are thus not modeled. Frame is maintained: the CDS length must always be a multiple of ...
Gene Conversion as a Source of Nucleotide Diversity in
... both, all except possibly one are consistent with an origin by gene conversion. This result is supported not only by the identity of the polymorphic nucleotides but also by the significant clustering of polymorphic nucleotides within each gene. Positioning of the polymorphisms within derived three-d ...
... both, all except possibly one are consistent with an origin by gene conversion. This result is supported not only by the identity of the polymorphic nucleotides but also by the significant clustering of polymorphic nucleotides within each gene. Positioning of the polymorphisms within derived three-d ...
OCA2 polymorphisms associated Distribution of two with pigmentation in East-Asian populations DATA REPORT
... frequencies in a broad East-Asian region, whereas the derived allele of rs74653330 is primarily restricted to northern East Asia. Our data suggest that these polymorphisms may have been selected independently in different regions of East Asia. Human Genome Variation (2015) 2, 15058; doi:10.1038/hgv. ...
... frequencies in a broad East-Asian region, whereas the derived allele of rs74653330 is primarily restricted to northern East Asia. Our data suggest that these polymorphisms may have been selected independently in different regions of East Asia. Human Genome Variation (2015) 2, 15058; doi:10.1038/hgv. ...
Identifying a Novel Isoform of the AZIN1 Gene by Combining High
... reading frame that would change the terminus of the subsequent protein from Ser-Asp-Glu-Asp-stop to PheArg-stop. Follow-up studies could validate this finding on the protein level and then measure gene expression of this new isoform in various tissues, subjects, and time-points. Moreover, the method ...
... reading frame that would change the terminus of the subsequent protein from Ser-Asp-Glu-Asp-stop to PheArg-stop. Follow-up studies could validate this finding on the protein level and then measure gene expression of this new isoform in various tissues, subjects, and time-points. Moreover, the method ...
Recombinant DNA Technology
... genes for antibiotic resistance. Chromosomal DNA is linear DNA. (Human DNA contains both introns and exons whereas plasmid DNA does not contain introns.) Scientists use plasmids as cloning vectors to transfer a human gene into bacterial cells for cloning and production of a desired protein. What wou ...
... genes for antibiotic resistance. Chromosomal DNA is linear DNA. (Human DNA contains both introns and exons whereas plasmid DNA does not contain introns.) Scientists use plasmids as cloning vectors to transfer a human gene into bacterial cells for cloning and production of a desired protein. What wou ...
Chapter 14.1
... In males, a defective allele for any of these genes results in colorblindness, an inability to distinguish certain colors. The most common form, red-green colorblindness, occurs in about 1 in 12 males. Among females, however, colorblindness affects only about 1 in 200. In order for a recessive allel ...
... In males, a defective allele for any of these genes results in colorblindness, an inability to distinguish certain colors. The most common form, red-green colorblindness, occurs in about 1 in 12 males. Among females, however, colorblindness affects only about 1 in 200. In order for a recessive allel ...
Transposons ※ Transposons are DNA elements that can hop, or
... place in DNA to another. They are also called “jumping genes”. They carry the enzyme, transposase responsible for transposition, the movement by a transposon. ※ They are discovered by Barbara McClintock in the early 1950s. ※ The transposons now exist in all organisms on the earth, including human. ※ ...
... place in DNA to another. They are also called “jumping genes”. They carry the enzyme, transposase responsible for transposition, the movement by a transposon. ※ They are discovered by Barbara McClintock in the early 1950s. ※ The transposons now exist in all organisms on the earth, including human. ※ ...
Characterization of two rice DNA methyltransferases
... libraries. OsMET1-1 has an open reading frame of 4,566 nucleotides with twelve exons and eleven introns while OsMET1-2 has an open reading frame of 4,452 nucleotides with eleven exons and ten introns. Although OsMET1-1 and OsMET1-2 have high sequence similarity overall, they share only 24% identity ...
... libraries. OsMET1-1 has an open reading frame of 4,566 nucleotides with twelve exons and eleven introns while OsMET1-2 has an open reading frame of 4,452 nucleotides with eleven exons and ten introns. Although OsMET1-1 and OsMET1-2 have high sequence similarity overall, they share only 24% identity ...
Rate Asymmetry After Genome Duplication Causes Substantial
... topologies among neighbor-joining (NJ) trees drawn from different loci and suggested that this conflict was the result of ‘‘asynchronous functional divergence’’ of duplicated genes (Langkjaer, R. B., P. F. Cliften, M. Johnston, and J. Piskur. 2003. Yeast genome duplication was followed by asynchrono ...
... topologies among neighbor-joining (NJ) trees drawn from different loci and suggested that this conflict was the result of ‘‘asynchronous functional divergence’’ of duplicated genes (Langkjaer, R. B., P. F. Cliften, M. Johnston, and J. Piskur. 2003. Yeast genome duplication was followed by asynchrono ...
Current Awareness Of Issues Related To Genetically Modified Food
... for introduction of a transgene at a very high copy number per plant cell if introduced into a chloroplast. This has advantages if the transgene is one that it is desirable to have expressed at a high level in the plant cells. Chloroplast inheritance is maternal in most flowering plants and is achie ...
... for introduction of a transgene at a very high copy number per plant cell if introduced into a chloroplast. This has advantages if the transgene is one that it is desirable to have expressed at a high level in the plant cells. Chloroplast inheritance is maternal in most flowering plants and is achie ...
Genes without frontiers?
... Gene flow across distantly related bacterial groups (horizontal gene transfer) is a major feature of bacterial evolution (Maynard Smith et al, 1991; Campbell, 2000; Ochman et al, 2000; Gogarten et al, 2002). This evolution need not be slow. The intense selection pressure imposed on microbial communi ...
... Gene flow across distantly related bacterial groups (horizontal gene transfer) is a major feature of bacterial evolution (Maynard Smith et al, 1991; Campbell, 2000; Ochman et al, 2000; Gogarten et al, 2002). This evolution need not be slow. The intense selection pressure imposed on microbial communi ...
chapter 15 - Issaquah Connect
... of the genetic loci along a particular chromosome and hypothesized that the frequency of recombinant offspring reflected the distance between genes on a chromosome. Sturtevant predicted the farther apart two genes are, the _________ the probability a crossover will occur, and therefore, the higher ...
... of the genetic loci along a particular chromosome and hypothesized that the frequency of recombinant offspring reflected the distance between genes on a chromosome. Sturtevant predicted the farther apart two genes are, the _________ the probability a crossover will occur, and therefore, the higher ...
Phylogeny, taxonomy, and evolution of the endothelin receptor gene
... along the basal internode that interconnects the two most recent common ancestors of the two groups. The most obvious example of a type II position is one that is fixed for radically different amino acids between therians and non-therians. In contrast, a conserved position is one with a constant site ...
... along the basal internode that interconnects the two most recent common ancestors of the two groups. The most obvious example of a type II position is one that is fixed for radically different amino acids between therians and non-therians. In contrast, a conserved position is one with a constant site ...
as a PDF
... Investigations of lampbrush chromosomes and the nucleolar organizer have suggested that each gene may be duplicated many times in consecutive linear series within one DNA molecule. This conclusion is in direct conflict with recombination data which indicate, not only that each gene is represented on ...
... Investigations of lampbrush chromosomes and the nucleolar organizer have suggested that each gene may be duplicated many times in consecutive linear series within one DNA molecule. This conclusion is in direct conflict with recombination data which indicate, not only that each gene is represented on ...
Isolation of a gene encoding a novel chloroplast protein by T
... upstream of the stop codon. A fusion protein, seven amino acids longer than its wild-type counterpart of Mr 46 251, is therefore synthesized in the pale mutant. Transcript analysis during dark-light transition, in vitro protein transport assay, and the absence of DNA sequence homology between cs and ...
... upstream of the stop codon. A fusion protein, seven amino acids longer than its wild-type counterpart of Mr 46 251, is therefore synthesized in the pale mutant. Transcript analysis during dark-light transition, in vitro protein transport assay, and the absence of DNA sequence homology between cs and ...
Two groups of human herpesvirus 6 identified by sequence
... group A (U 1102) and group B (Z29) show in addition to extensive DNA cross-hybridization an identical genome structure, base composition and size. These are AT-rich, 162 kbp genomes bounded by direct terminal repeats (Martin et al., 1991; Lindquester & Pellett, 1991). In this study we investigated t ...
... group A (U 1102) and group B (Z29) show in addition to extensive DNA cross-hybridization an identical genome structure, base composition and size. These are AT-rich, 162 kbp genomes bounded by direct terminal repeats (Martin et al., 1991; Lindquester & Pellett, 1991). In this study we investigated t ...
The nucleotide sequence of Saccharomyces cerevisiae
... helices which, when present in a bundle, can contribute to the formation of a polar channel within the lipid bilayer. Of the 572 ORFs, 359 (63 %) show no predicted transmembrane spans or are known to be soluble, 79 (14 %) carry at least three putative spans or are known to be membrane bound, and 134 ...
... helices which, when present in a bundle, can contribute to the formation of a polar channel within the lipid bilayer. Of the 572 ORFs, 359 (63 %) show no predicted transmembrane spans or are known to be soluble, 79 (14 %) carry at least three putative spans or are known to be membrane bound, and 134 ...
Ch. 7: Presentation Slides
... • When chromosome 21 is one of the acrocentrics in a Robertsonian translocation, the rearrangement leads to a familial type of Down syndrome • The heterozygous carrier is phenotypically normal, but a high risk of Down syndrome results from aberrant segregation in meiosis • Approximately 3 percent of ...
... • When chromosome 21 is one of the acrocentrics in a Robertsonian translocation, the rearrangement leads to a familial type of Down syndrome • The heterozygous carrier is phenotypically normal, but a high risk of Down syndrome results from aberrant segregation in meiosis • Approximately 3 percent of ...
Fighting the good cause: meaning, purpose
... Many four-‐‑year-‐‑olds delight in asking “Why?” and when one offers an explanation, respond with another “Why?” requesting an explanation of the explanation, until explanatory exhaustion. Aristotle and Thomas Aquinas used the threatened infinite regress of c ...
... Many four-‐‑year-‐‑olds delight in asking “Why?” and when one offers an explanation, respond with another “Why?” requesting an explanation of the explanation, until explanatory exhaustion. Aristotle and Thomas Aquinas used the threatened infinite regress of c ...
Fine Mapping of Two Wheat Powdery Mildew Resistance Genes
... et al., 2012). Barley (Hordeum vulgare L.) Mla (Wei et al., 1999), maize (Zea mays L.) Rp1 (Ramakrishna et al., 2002; Smith et al., 2004), and lettuce (Lactuca sativa L.) RGC2 (Meyers et al., 1998) are all known R-gene clusters. The Rp1 encompassed up to >50 copies of R genes was probably the larges ...
... et al., 2012). Barley (Hordeum vulgare L.) Mla (Wei et al., 1999), maize (Zea mays L.) Rp1 (Ramakrishna et al., 2002; Smith et al., 2004), and lettuce (Lactuca sativa L.) RGC2 (Meyers et al., 1998) are all known R-gene clusters. The Rp1 encompassed up to >50 copies of R genes was probably the larges ...
Human genome
The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.