An exo-b-( 1,3)-glucanase of Candida albicans
... bands in the C . kefyr medium may represent several related gene products or heterogeneity arising from posttranslational modification of one gene product. The M , 56000 band in the S. cerevisiae sample is as expected for the major glycosylated form of the exoglucanase secreted by this species (Rami ...
... bands in the C . kefyr medium may represent several related gene products or heterogeneity arising from posttranslational modification of one gene product. The M , 56000 band in the S. cerevisiae sample is as expected for the major glycosylated form of the exoglucanase secreted by this species (Rami ...
Identification of a Novel Streptococcal Gene
... autocatalytic cleavage of the Ala84-Gly85 bond of LexA, which disrupts its ability to dimerize (35, 57). Self-cleavage of LexA inactivates LexA as a repressor, which induces the expression of SOS genes. SOS mutagenesis is mainly mediated by errorprone polymerases and takes place under severe conditi ...
... autocatalytic cleavage of the Ala84-Gly85 bond of LexA, which disrupts its ability to dimerize (35, 57). Self-cleavage of LexA inactivates LexA as a repressor, which induces the expression of SOS genes. SOS mutagenesis is mainly mediated by errorprone polymerases and takes place under severe conditi ...
Molecular Coat Colour Genetics
... Bailey et al., 2002). The high level of sequence identity provides an ample substrate for recombination events. Furthermore, nearly identical sequence copies in the genome created by duplications may lead to large-scale chromosomal rearrangements, such as deletions, inversions, translocations and ad ...
... Bailey et al., 2002). The high level of sequence identity provides an ample substrate for recombination events. Furthermore, nearly identical sequence copies in the genome created by duplications may lead to large-scale chromosomal rearrangements, such as deletions, inversions, translocations and ad ...
Heritable genome-wide variation of gene expression and promoter methylation between
... To verify the results of the array-based methylation analysis, we arbitrarily selected four genes, which were DM on the tiling arrays in either parents or offspring, FUCA1, PCDHAC1, TXNDC16, and RUFY3, and replicated the findings for those, using a different technique and a different animal material ...
... To verify the results of the array-based methylation analysis, we arbitrarily selected four genes, which were DM on the tiling arrays in either parents or offspring, FUCA1, PCDHAC1, TXNDC16, and RUFY3, and replicated the findings for those, using a different technique and a different animal material ...
Stanford Profiles: /viewBiosketch - CAP Network
... Linking Collagen Genotypes to Molecular Phenotypes The long-term goal of this proposal is to determine the chemical, physical and structural properties of biopolymers in the context of natural sequence variation. Mutations in type I collagen lead to an array of minor to lethal disorders. Osteogenesi ...
... Linking Collagen Genotypes to Molecular Phenotypes The long-term goal of this proposal is to determine the chemical, physical and structural properties of biopolymers in the context of natural sequence variation. Mutations in type I collagen lead to an array of minor to lethal disorders. Osteogenesi ...
RNA Tertiary Structure
... Ninety eight percent of the human genome does not code for protein. What is its function? ...
... Ninety eight percent of the human genome does not code for protein. What is its function? ...
The Recombinant DNA Controversy: A Contemporary
... or gene cloner does. The million sheets of paper cannot be confused with a million cars. The many copies of a gene generated through recombinant DNA technology stand in precisely the same relation to the organism from which the gene was isolated as does the stack of paper to the car. Indeed the anal ...
... or gene cloner does. The million sheets of paper cannot be confused with a million cars. The many copies of a gene generated through recombinant DNA technology stand in precisely the same relation to the organism from which the gene was isolated as does the stack of paper to the car. Indeed the anal ...
Correlations Between Gene Expression and Gene Conservation in
... three gene categories among genes regulated during sexual differentiation (Mata et al. 2002). Unlike the comparisons in Figure 1, the following analyses do not consider absolute levels of gene expression, but are based on relative expression levels (meiotic vs. vegetative expression). We found that ...
... three gene categories among genes regulated during sexual differentiation (Mata et al. 2002). Unlike the comparisons in Figure 1, the following analyses do not consider absolute levels of gene expression, but are based on relative expression levels (meiotic vs. vegetative expression). We found that ...
A virulence-associated gene microarray: a tool for
... contributed by virulence-associated genes (Fitzgerald et al., 2001). This ensures that strains present a variable antigenic profile to the host and may limit the effective immunity of the population to colonization. S. aureus strains carry a range of genes that confer resistance to a growing list of ...
... contributed by virulence-associated genes (Fitzgerald et al., 2001). This ensures that strains present a variable antigenic profile to the host and may limit the effective immunity of the population to colonization. S. aureus strains carry a range of genes that confer resistance to a growing list of ...
Crossing over - JeongAPbiology
... 1) synapsis and crossing over do not occur in mitosis 2) at metaphase I, homologous pairs are lined up, but in mitosis invidivual chromosomes lined up 3) Anaphase 1 chromosomes move to opposite poles, but in mitosis, the sister chromatids ...
... 1) synapsis and crossing over do not occur in mitosis 2) at metaphase I, homologous pairs are lined up, but in mitosis invidivual chromosomes lined up 3) Anaphase 1 chromosomes move to opposite poles, but in mitosis, the sister chromatids ...
CHAPTER 6
... • In terms of genetic information, this corresponds to "N to C" in proteins. • The base sequence of a nucleic acid is its distinctive characteristic. • pGpApCpU, GpApCpUp, pGpApCpUp, GACU, dGACT Garrett and Grisham, Biochemistry, Third Edition ...
... • In terms of genetic information, this corresponds to "N to C" in proteins. • The base sequence of a nucleic acid is its distinctive characteristic. • pGpApCpU, GpApCpUp, pGpApCpUp, GACU, dGACT Garrett and Grisham, Biochemistry, Third Edition ...
7. APPLICATIONS - UTH e
... Microsatellite DNA Methodology Microsatellites (sometimes referred to as a variable number of tandem repeats or VNTRs) are short segments of DNA that have a repeated sequence such as CACACACA, and they tend to occur in non-coding DNA. In some microsatellites, the repeated unit (e.g. CA) may occu ...
... Microsatellite DNA Methodology Microsatellites (sometimes referred to as a variable number of tandem repeats or VNTRs) are short segments of DNA that have a repeated sequence such as CACACACA, and they tend to occur in non-coding DNA. In some microsatellites, the repeated unit (e.g. CA) may occu ...
Pairwise sequence alignment - uni
... Ideal for looking for features that may come in different orders Reveal complex patterns Benefit from the most sophisticated statistical‐analysis tool in the universe . . . your brain ...
... Ideal for looking for features that may come in different orders Reveal complex patterns Benefit from the most sophisticated statistical‐analysis tool in the universe . . . your brain ...
Less mastitis through targeted selective breeding Why a reduction of
... clinical and subclinical mastitis. The sizes of these genomic regions were typically in the range of several million DNA base pairs. Each region contained a plethora of genes of which some play a critical role in mastitis resistance either as single genes or in combination. They can, for example, al ...
... clinical and subclinical mastitis. The sizes of these genomic regions were typically in the range of several million DNA base pairs. Each region contained a plethora of genes of which some play a critical role in mastitis resistance either as single genes or in combination. They can, for example, al ...
INTRODUCTOR Y BIOTECHNOLOGY (ABG 504) THEORETICAL MODULE BY
... structure (i.e., shaped like a corkscrew).[18][19] Their double-helix model had two strands of DNA with the nucleotides pointing inward, each matching a complementary nucleotide on the other strand to form what looks like rungs on a twisted ladder.[20] This structure showed that genetic information ...
... structure (i.e., shaped like a corkscrew).[18][19] Their double-helix model had two strands of DNA with the nucleotides pointing inward, each matching a complementary nucleotide on the other strand to form what looks like rungs on a twisted ladder.[20] This structure showed that genetic information ...
Convergent evolution of genes controlling mitonuclear
... Here, we investigated the pattern of positive selection in annual (i.e. short-lived) and non-annual (i.e. long-lived) African killifishes to identify a genomic substrate for evolution of annual life history (and reduced lifespan). We identified genes under positive selection in all mitonuclear balan ...
... Here, we investigated the pattern of positive selection in annual (i.e. short-lived) and non-annual (i.e. long-lived) African killifishes to identify a genomic substrate for evolution of annual life history (and reduced lifespan). We identified genes under positive selection in all mitonuclear balan ...
E.Publication
... decided to do. They have set out to learn the language of the genes. This international effort is called the Human Genome Project. The United States is spending 3 billion dollars over 15 years on this project. Other countries also are investing large amounts on research. It is a huge undertaking tha ...
... decided to do. They have set out to learn the language of the genes. This international effort is called the Human Genome Project. The United States is spending 3 billion dollars over 15 years on this project. Other countries also are investing large amounts on research. It is a huge undertaking tha ...
Gene Section XPC (xeroderma pigmentosum, complementation group C) Atlas of Genetics and Cytogenetics
... genes. It is very likely that the XPC-HR23B complex is the principal damage recognition complex i.e. essential for the recognition of DNA lesions in the genome. Binding of XPC-HR23B to a DNA lesion causes local unwinding, so that the XPA protein can bind and the whole repair machinery can be loaded ...
... genes. It is very likely that the XPC-HR23B complex is the principal damage recognition complex i.e. essential for the recognition of DNA lesions in the genome. Binding of XPC-HR23B to a DNA lesion causes local unwinding, so that the XPA protein can bind and the whole repair machinery can be loaded ...
Characterization of Two Rice MADS Box Genes That Control
... protein (Figs. 1 and 2). This region is the most conserved region as observed from other MADS box genes. The second conserved domain, the K box, is located between the residues 95 and 160 in both OsMADS7 and OsMADS8 (Figs. 1 and 2) . The genes contain two variable regions, the I region between the M ...
... protein (Figs. 1 and 2). This region is the most conserved region as observed from other MADS box genes. The second conserved domain, the K box, is located between the residues 95 and 160 in both OsMADS7 and OsMADS8 (Figs. 1 and 2) . The genes contain two variable regions, the I region between the M ...
Diapositive 1 - Institut Pasteur
... ● Although deletion analyses of PE/PPE genes were accompanied with phenotypic characteristics, the detailed molecular mechanisms responsible for the observed effects remain to be demonstrated ...
... ● Although deletion analyses of PE/PPE genes were accompanied with phenotypic characteristics, the detailed molecular mechanisms responsible for the observed effects remain to be demonstrated ...
5. Harmful mutations
... biggest difference between DNA and RNA. Another difference is that RNA molecules can have a much greater variety of nucleic acid bases. DNA has mostly just 4 different bases with a few extra occasionally. The difference in these bases (between DNA and RNA) allows RNA molecules to assume a wide varie ...
... biggest difference between DNA and RNA. Another difference is that RNA molecules can have a much greater variety of nucleic acid bases. DNA has mostly just 4 different bases with a few extra occasionally. The difference in these bases (between DNA and RNA) allows RNA molecules to assume a wide varie ...
Cosmid walking and chromosome jumping in the region of PKD1
... Having identified the order of 26.6PROX and 26.6DIS, further attempts were made to extend the walk beyond cos7 in a distal direction towards the opposite flanking markers. These attempts were unsuccessful. To overcome this problem, a Noll jumping library was constructed. Such a library allows chromo ...
... Having identified the order of 26.6PROX and 26.6DIS, further attempts were made to extend the walk beyond cos7 in a distal direction towards the opposite flanking markers. These attempts were unsuccessful. To overcome this problem, a Noll jumping library was constructed. Such a library allows chromo ...
Gene Section NEIL1 (nei endonuclease VIII-like 1 (E. coli))
... deoxyribo-5'-phosphate (dRP) and excised by a dRP lyase (dRPase) activity of DNA polymerase beta. Since NEIL1 also has dRPase activity, NEIL1 has a role as a backup dRPase in mammalian cells. (5) NEIL1 has a repair activity for oxidized bases in single-strand DNA and bubble DNA, suggesting a possibi ...
... deoxyribo-5'-phosphate (dRP) and excised by a dRP lyase (dRPase) activity of DNA polymerase beta. Since NEIL1 also has dRPase activity, NEIL1 has a role as a backup dRPase in mammalian cells. (5) NEIL1 has a repair activity for oxidized bases in single-strand DNA and bubble DNA, suggesting a possibi ...
Identification of genes that are associated with DNA repeats in
... in the prokaryotic species is indicated in Table 1. For species for which the complete genome has not yet been published, the presence or absence of the cas genes is indicated. For those species whose genomes have been published the gene numbers of the cas genes are indicated. The positions of the c ...
... in the prokaryotic species is indicated in Table 1. For species for which the complete genome has not yet been published, the presence or absence of the cas genes is indicated. For those species whose genomes have been published the gene numbers of the cas genes are indicated. The positions of the c ...
Human genome
The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.