Lecture 6A/ Chapter 6 Protein
									
... • When absorbed proteins are either: used for energy, synthesis (structure, facilitate, regulate) or transported to the liver. See Fig. 6.6. Protein Digestion in the GI Tract ...
                        	... • When absorbed proteins are either: used for energy, synthesis (structure, facilitate, regulate) or transported to the liver. See Fig. 6.6. Protein Digestion in the GI Tract ...
									L1-2
									
... • ~70,000 proteins in humans • ~21,000 structures known • Only 6 classes of protein folds – Class a: bundles of a helices connected by loops on surface of proteins – Class b: antiparallel b sheets, usually two sheets in close contact forming sandwich – Class a/b: mainly parallel b sheets with interv ...
                        	... • ~70,000 proteins in humans • ~21,000 structures known • Only 6 classes of protein folds – Class a: bundles of a helices connected by loops on surface of proteins – Class b: antiparallel b sheets, usually two sheets in close contact forming sandwich – Class a/b: mainly parallel b sheets with interv ...
									amino acid
									
... • There can be many different regulators acting on a single gene – i.e. more signal integration than in bacteria. • Alternate splicing can give rise to more than one protein product from a single ‘gene’. • Predicting genes (introns, exons and proper splicing) is very challenging. • Because the contr ...
                        	... • There can be many different regulators acting on a single gene – i.e. more signal integration than in bacteria. • Alternate splicing can give rise to more than one protein product from a single ‘gene’. • Predicting genes (introns, exons and proper splicing) is very challenging. • Because the contr ...
									What Do I already know about Prehistoric Cultures?
									
... • most plant foods contain limited amounts of one or two amino acids • for this reason single-item diets, such as those made up almost solely of corn or yams, can lead to protein deficiency The Cultural Feast, 2nd Ed., p. 52 ...
                        	... • most plant foods contain limited amounts of one or two amino acids • for this reason single-item diets, such as those made up almost solely of corn or yams, can lead to protein deficiency The Cultural Feast, 2nd Ed., p. 52 ...
									PAPER 1 1.Which pair of features is correct for both plant and
									
... Two chromosomes with differing sets of genes, in the same sequence, with the same alleles B. Two chromosomes with the same set of genes, in a different sequence, with the same alleles C. Two chromosomes with a different set of genes, in the same sequence, with different alleles D. Two chromosomes wi ...
                        	... Two chromosomes with differing sets of genes, in the same sequence, with the same alleles B. Two chromosomes with the same set of genes, in a different sequence, with the same alleles C. Two chromosomes with a different set of genes, in the same sequence, with different alleles D. Two chromosomes wi ...
									Full size lecture slides (PDF file, 660 kB)
									
... differently: cannot be broken down by the enzymes found in animals • Cows and other ruminants can digest cellulose by means of bacteria that live in their intestines which provide the ...
                        	... differently: cannot be broken down by the enzymes found in animals • Cows and other ruminants can digest cellulose by means of bacteria that live in their intestines which provide the ...
									or protein
									
... different amino acids, namely, the amino acid composition was used to distinguish different proteins before the days of protein sequencing. ...
                        	... different amino acids, namely, the amino acid composition was used to distinguish different proteins before the days of protein sequencing. ...
									Calliphorin, a Protein Involved in the Cuticle Formation
									
... blowflies, its physiological significance is still un known. It is generally thought that calliphorin may be a storage protein which functions as a source of nutrients for adult proteins. It may also play a role in providing haemolymph with amino acids to sustain osmotic pressure. Considering the f ...
                        	... blowflies, its physiological significance is still un known. It is generally thought that calliphorin may be a storage protein which functions as a source of nutrients for adult proteins. It may also play a role in providing haemolymph with amino acids to sustain osmotic pressure. Considering the f ...
									Review on Biochemistry: Protein Chemistry
									
...  -carboxyglutamate: found in prothrombin and certain Ca2+-binding protein.  Desmosine (a derivative of four Lys residues): found in the fibrous protein elastin.  Selenocysteine: Selenium replaces sulfur in cysteine during amino acid synthesis (derived from serine).  Amino acids not as constitue ...
                        	...  -carboxyglutamate: found in prothrombin and certain Ca2+-binding protein.  Desmosine (a derivative of four Lys residues): found in the fibrous protein elastin.  Selenocysteine: Selenium replaces sulfur in cysteine during amino acid synthesis (derived from serine).  Amino acids not as constitue ...
									interpreted as a demonstration of a biologically significant protein
									
... the protein from the reagents by passing the reaction mixture over a 10ml column of Sephadex G-25. The column is disposed of as radioactive waste at the end of the procedure. The column is initially prepared in the cold room and the buffer is kept on ice, but just before use it is brought into the f ...
                        	... the protein from the reagents by passing the reaction mixture over a 10ml column of Sephadex G-25. The column is disposed of as radioactive waste at the end of the procedure. The column is initially prepared in the cold room and the buffer is kept on ice, but just before use it is brought into the f ...
									DYMATIZE
									
... preserve the many important whey protein fractions including lactoferrin and immunoglobins, which can be lost in other forms of processing. We have carefully formulated ISO•100 to deliver more of what you want, and less of what you don’t want: free of gluten, fat, sugar, and lactose, plus only one g ...
                        	... preserve the many important whey protein fractions including lactoferrin and immunoglobins, which can be lost in other forms of processing. We have carefully formulated ISO•100 to deliver more of what you want, and less of what you don’t want: free of gluten, fat, sugar, and lactose, plus only one g ...
									Communication - Dundee Life Sciences
									
... Blocked in a DtatC Mutant—To test the role of the tatC gene product we constructed a strain in which the tatC gene was inactivated by an in-frame deletion as described under “Experimental Procedures.” The deletion strain is viable under aerobic respiratory or fermentative growth conditions, indicati ...
                        	... Blocked in a DtatC Mutant—To test the role of the tatC gene product we constructed a strain in which the tatC gene was inactivated by an in-frame deletion as described under “Experimental Procedures.” The deletion strain is viable under aerobic respiratory or fermentative growth conditions, indicati ...
									BICH 605
									
... subunits of different molecular size will be resolved into constituent polypeptides. Screen fractions during protein purification. Quaternary structure profile: Comparison of the protein bands obtained under non-reducing and reducing conditions provides information about the molecular size of subuni ...
                        	... subunits of different molecular size will be resolved into constituent polypeptides. Screen fractions during protein purification. Quaternary structure profile: Comparison of the protein bands obtained under non-reducing and reducing conditions provides information about the molecular size of subuni ...
									lecture 5
									
... Figure 2. Overall Structure of PDI (A) Ribbon diagram of PDI with the a, b, b′, and a′ domains in magenta, cyan, yellow, and red, respectively, and the C-terminal extension in green. The two orientations roughly differ by a 90° rotation around the horizontal axis. The side chains of the active site ...
                        	... Figure 2. Overall Structure of PDI (A) Ribbon diagram of PDI with the a, b, b′, and a′ domains in magenta, cyan, yellow, and red, respectively, and the C-terminal extension in green. The two orientations roughly differ by a 90° rotation around the horizontal axis. The side chains of the active site ...
									BICH 303 Exam #1 Fall 2005 1. Amphiphilic or amphipathic
									
... b genomic economy: less DNA required to code for a monomer that forms a homodimer. c. catalytic site: the monomer may not constitute a complete enzyme active site. The active site may only form in the oligomer using side chains from two-or-more monomers. d. substrate channeling: oligomeric enzymes m ...
                        	... b genomic economy: less DNA required to code for a monomer that forms a homodimer. c. catalytic site: the monomer may not constitute a complete enzyme active site. The active site may only form in the oligomer using side chains from two-or-more monomers. d. substrate channeling: oligomeric enzymes m ...
									Gene Section EIF4EBP1 (Eukaryotic translation initiation factor 4E binding protein 1)
									
... another initiation factor, eIF4G, that is essential for polypeptide chain initiation. Thus the availability of eIF4E for translation of cap-dependent mRNAs is limited by the extent to which this factor is sequestered by the 4E-BPs. 4E-BP1 is reversibly phosphorylated at multiple sites (see diagram a ...
                        	... another initiation factor, eIF4G, that is essential for polypeptide chain initiation. Thus the availability of eIF4E for translation of cap-dependent mRNAs is limited by the extent to which this factor is sequestered by the 4E-BPs. 4E-BP1 is reversibly phosphorylated at multiple sites (see diagram a ...
									Gene Section GBP1 (guanylate binding protein 1, interferon- inducible, 67kDa)
									
... The human GBP family comprises 7 highly homologous members, all located on the chromosome 1. GBP-1 is to 77% similar to GBP-2, 88% to GBP-3, 56% to GBP-4, 68% to GBP-5, 54% to GBP-6 and 56% to GBP-7. Homologues have been found in various species like zebrafish, chimpanzee (99% homology), rat, dog or ...
                        	... The human GBP family comprises 7 highly homologous members, all located on the chromosome 1. GBP-1 is to 77% similar to GBP-2, 88% to GBP-3, 56% to GBP-4, 68% to GBP-5, 54% to GBP-6 and 56% to GBP-7. Homologues have been found in various species like zebrafish, chimpanzee (99% homology), rat, dog or ...
									Review Questions
									
... The next level is called the tertiary level. Tertiary means “third”. The polypeptide continues to bond to itself but this time the individual amino acids join to each other by bonds between their R groups. Remember, the 20 kinds of amino acids differ because of their R groups. These R groups also h ...
                        	... The next level is called the tertiary level. Tertiary means “third”. The polypeptide continues to bond to itself but this time the individual amino acids join to each other by bonds between their R groups. Remember, the 20 kinds of amino acids differ because of their R groups. These R groups also h ...
									2.1 2 Translation - Pearson Schools and FE Colleges
									
... A What do you think the effect of cAMP is on the activity of the enzyme glycogen synthase and how do you think the effect is brought about? B What do you think the effect of G-6-P is on the activity of glycogen synthase? ...
                        	... A What do you think the effect of cAMP is on the activity of the enzyme glycogen synthase and how do you think the effect is brought about? B What do you think the effect of G-6-P is on the activity of glycogen synthase? ...
Interactome
                        In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.