The Physiological Roles of Enzymes
... the RNA molecule is removed while the parts on either side of this intron are reconnected. b. Other RNA molecules that do not undergo self-splicing can act on other molecules as substrates are true catalysts. i. Ribonuclease P cleaves transfer RNA precursors to their mature ...
... the RNA molecule is removed while the parts on either side of this intron are reconnected. b. Other RNA molecules that do not undergo self-splicing can act on other molecules as substrates are true catalysts. i. Ribonuclease P cleaves transfer RNA precursors to their mature ...
Lecture #7
... reaction decreases as inhibitor conc. increases, at saturation rate of reaction will be nil. Non competitive irreversible inhibition e.g heavy metals, nerve gas contains a compound that combines with serine in active site of acetylcholinesterase, and stops acetylcholine from binding. Causes accumu ...
... reaction decreases as inhibitor conc. increases, at saturation rate of reaction will be nil. Non competitive irreversible inhibition e.g heavy metals, nerve gas contains a compound that combines with serine in active site of acetylcholinesterase, and stops acetylcholine from binding. Causes accumu ...
Amino Acid Sidechains
... Every acidic or basic group on a molecule has a different “pK” (K is the dissociation constant) value. The relationship between the pH of the solution it is in and the pK of the ionizable group will determine the predominant form of the ionizable group. Every acidic or basic group has an “acid form” ...
... Every acidic or basic group on a molecule has a different “pK” (K is the dissociation constant) value. The relationship between the pH of the solution it is in and the pK of the ionizable group will determine the predominant form of the ionizable group. Every acidic or basic group has an “acid form” ...
Unit 3: Chapter 6
... i. all complex carbohydrates are _______________ of __________ joined together by ___________________ ii. ____saccharide ___saccharide _____saccharide iii. Glucose is the most common monosaccharide ...
... i. all complex carbohydrates are _______________ of __________ joined together by ___________________ ii. ____saccharide ___saccharide _____saccharide iii. Glucose is the most common monosaccharide ...
Practice Exam 1
... a). KM will decrease. b). No change. c). Observed rate will be faster. d). kcat will increase. e). Observed rate will be slower. 3). The basis for enzyme-substrate specificity is: a). shape/geometry. b). Keq. c). stereospecificity. d). electronic complementarity. e). none of the above. f). a, d, and ...
... a). KM will decrease. b). No change. c). Observed rate will be faster. d). kcat will increase. e). Observed rate will be slower. 3). The basis for enzyme-substrate specificity is: a). shape/geometry. b). Keq. c). stereospecificity. d). electronic complementarity. e). none of the above. f). a, d, and ...
The Chemistry of Life
... or the accumulation of product Rate of reaction is the slope of the linear portion of the graph Reaction rate is affected by pH, substrate conc., enzyme conc., temperature, and ...
... or the accumulation of product Rate of reaction is the slope of the linear portion of the graph Reaction rate is affected by pH, substrate conc., enzyme conc., temperature, and ...
7-JF-S`15
... Regulation of metabolic pathways In Feedback Inhibition, high concentration of the product of a pathway controls the rate of its own synthesis by inhibiting an early step Flux through the pathway is regulated depending on the concentration of Product (K below) In Allosteric Activation, high concent ...
... Regulation of metabolic pathways In Feedback Inhibition, high concentration of the product of a pathway controls the rate of its own synthesis by inhibiting an early step Flux through the pathway is regulated depending on the concentration of Product (K below) In Allosteric Activation, high concent ...
Chapter 6, Section 3
... Organic: contains carbon ◦ All living things contain carbon (C), hydrogen (H), oxygen (O), nitrogen (N), and phosphorus (P) Monomer: created when C,H,O, N, P bond together to form small molecules Polymer: large compounds that are formed by joining monomers together ...
... Organic: contains carbon ◦ All living things contain carbon (C), hydrogen (H), oxygen (O), nitrogen (N), and phosphorus (P) Monomer: created when C,H,O, N, P bond together to form small molecules Polymer: large compounds that are formed by joining monomers together ...
Chapter 5 notes cont.
... At any moment in the cell's life, the specific enzymes that are present and active determine which reactions occur. ...
... At any moment in the cell's life, the specific enzymes that are present and active determine which reactions occur. ...
Enzymes/Macromolecules/Bonding
... Enzymes Enzymes are proteins that help to speed up chemical reactions in the body Shape of Enzyme determines its function High temperature or extreme pH values may effect the shape of an enzyme molecule (denaturing). Makes enzymes useless ...
... Enzymes Enzymes are proteins that help to speed up chemical reactions in the body Shape of Enzyme determines its function High temperature or extreme pH values may effect the shape of an enzyme molecule (denaturing). Makes enzymes useless ...
103 Rev Ex2 key Win06
... 26. What are two common functions of metal ions as cofactors? Metal ions often are involved in electron transfer (redox) reactions in the active site. They also can activate the substrate by interacting with electron-rich atoms on the amino acid side-chains. They stabilize the transition state, and ...
... 26. What are two common functions of metal ions as cofactors? Metal ions often are involved in electron transfer (redox) reactions in the active site. They also can activate the substrate by interacting with electron-rich atoms on the amino acid side-chains. They stabilize the transition state, and ...
Chem 464 Biochemistry
... Hypochromism refers to the fact that DNA has a lower absorbance at 260 nm that you would calculate based on the sum of the absorbancies of the monomers. This occurs because the bases stacked in the core of the helix have electronic interactions with the bases above and below them that change their l ...
... Hypochromism refers to the fact that DNA has a lower absorbance at 260 nm that you would calculate based on the sum of the absorbancies of the monomers. This occurs because the bases stacked in the core of the helix have electronic interactions with the bases above and below them that change their l ...
SI Worksheet 10 1. What does coupling reactions mean? The
... 14. Another word for a non-protein organic molecule is ______________. What is an example of one? Coenzymes, NAD+) “nicotinamide adenine dinucleotide”, they help enzymes do their thing 15. What is an important example of a cofactor in the body? Mg 2+, most of the cofactors are metal ions that are i ...
... 14. Another word for a non-protein organic molecule is ______________. What is an example of one? Coenzymes, NAD+) “nicotinamide adenine dinucleotide”, they help enzymes do their thing 15. What is an important example of a cofactor in the body? Mg 2+, most of the cofactors are metal ions that are i ...
Catalytic triad
A catalytic triad refers to the three amino acid residues that function together at the centre of the active site of some hydrolase and transferase enzymes (e.g. proteases, amidases, esterases, acylases, lipases and β-lactamases). An Acid-Base-Nucleophile triad is a common motif for generating a nucleophilic residue for covalent catalysis. The residues form a charge-relay network to polarise and activate the nucleophile, which attacks the substrate, forming a covalent intermediate which is then hydrolysed to regenerate free enzyme. The nucleophile is most commonly a serine or cysteine amino acid, but occasionally threonine. Because enzymes fold into complex three-dimensional structures, the residues of a catalytic triad can be far from each other along the amino-acid sequence (primary structure), however, they are brought close together in the final fold.As well as divergent evolution of function (and even the triad's nucleophile), catalytic triads show some of the best examples of convergent evolution. Chemical constraints on catalysis have led to the same catalytic solution independently evolving in at least 23 separate superfamilies. Their mechanism of action is consequently one of the best studied in biochemistry.