The New England Journal of Medicine Volume 344 Number 14 April 5, 2001
... dose cohorts, which ranged from 25 to 1000 mg per day. Doses of STI571 were administered orally once daily, except for 800 and 1000 mg, which were administered twice daily as doses of 400 and 500 mg, respectively. Patients received continuous daily therapy with STI571 unless unacceptable adverse eff ...
... dose cohorts, which ranged from 25 to 1000 mg per day. Doses of STI571 were administered orally once daily, except for 800 and 1000 mg, which were administered twice daily as doses of 400 and 500 mg, respectively. Patients received continuous daily therapy with STI571 unless unacceptable adverse eff ...
sarcoidosis Treatment Guide
... onset of general symptoms – such as weight loss, fatigue, fever or just an overall feeling of ill health – usually means that the course of sarcoidosis will be relatively short and mild in severity. Symptoms of shortness of breath and some types of skin involvement mean that sarcoidosis will be more ...
... onset of general symptoms – such as weight loss, fatigue, fever or just an overall feeling of ill health – usually means that the course of sarcoidosis will be relatively short and mild in severity. Symptoms of shortness of breath and some types of skin involvement mean that sarcoidosis will be more ...
acupuncture for cancer patients - Acupuncture | The Acupuncture
... menopausal symptoms in patients experiencing the normal climacteric. It may have this effect by raising serotonin levels which alter the temperature set point in the hypothalamus. Vasomotor symptoms can be extreme in breast cancer patients and patients with prostate cancer who are undergoing antican ...
... menopausal symptoms in patients experiencing the normal climacteric. It may have this effect by raising serotonin levels which alter the temperature set point in the hypothalamus. Vasomotor symptoms can be extreme in breast cancer patients and patients with prostate cancer who are undergoing antican ...
2012 ACCF/AHA Guideline for Management of Unstable Angina
... Clinical decision making should consider the quality and availability of expertise in the area where care is provided. When these guidelines are used as the basis for regulatory or payer decisions, the goal should be improvement in quality of care. The Task Force recognizes that situations arise for ...
... Clinical decision making should consider the quality and availability of expertise in the area where care is provided. When these guidelines are used as the basis for regulatory or payer decisions, the goal should be improvement in quality of care. The Task Force recognizes that situations arise for ...
Product Monograph
... percutaneous endoscopic gastrostomy-jejunostomy (PEG-J) and long-term use of PEG-J need to be balanced against the expected benefits of using DUODOPA (levodopa/carbidopa intestinal gel). See WARNINGS AND PRECAUTIONS, General Peri-Operative Considerations, Gastrointestinal, DUODOPA Treatment and Devi ...
... percutaneous endoscopic gastrostomy-jejunostomy (PEG-J) and long-term use of PEG-J need to be balanced against the expected benefits of using DUODOPA (levodopa/carbidopa intestinal gel). See WARNINGS AND PRECAUTIONS, General Peri-Operative Considerations, Gastrointestinal, DUODOPA Treatment and Devi ...
Management of Atopic Eczema Vol.13 No.5 2007
... Wet Wrap reatment (WWT) – The use of dampened bandages to reduce inflamed eczema is an old remedy (30), which generally requires hospital admission but has also been used in primary care (9). Experts agree that WWT is effective for the treatment of severe atopic eczema (30) but should be reserved fo ...
... Wet Wrap reatment (WWT) – The use of dampened bandages to reduce inflamed eczema is an old remedy (30), which generally requires hospital admission but has also been used in primary care (9). Experts agree that WWT is effective for the treatment of severe atopic eczema (30) but should be reserved fo ...
highlights of prescribing information
... corticosteroids. After withdrawal from systemic corticosteroids, a number of months are required for recovery of hypothalamic-pituitary-adrenal (HPA) function. Patients who have been previously maintained on 20 mg or more per day of prednisone (or its equivalent) may be most susceptible, particularl ...
... corticosteroids. After withdrawal from systemic corticosteroids, a number of months are required for recovery of hypothalamic-pituitary-adrenal (HPA) function. Patients who have been previously maintained on 20 mg or more per day of prednisone (or its equivalent) may be most susceptible, particularl ...
Common Vulvar Complaints and Management What`s Your
... Acitretin (Soriatane) .It can work well in low dose 30-70 mg/week. ( Isotretinoin has been used to treat oral lichen planus; however, discontinuation of the medication results in recurrence of the oral lesions.) Long-term use of retinoids may result in liver dysfunction.but not in the small doses re ...
... Acitretin (Soriatane) .It can work well in low dose 30-70 mg/week. ( Isotretinoin has been used to treat oral lichen planus; however, discontinuation of the medication results in recurrence of the oral lesions.) Long-term use of retinoids may result in liver dysfunction.but not in the small doses re ...
Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols
... 3. Severity of Symptoms: A symptom has significant severity if it substantially impacts (approximately a 50% reduction) on the patient’s life experience and activities. In assessing severity and impact, compare the patient’s activity level to their premorbid activity level. Establishing the severity ...
... 3. Severity of Symptoms: A symptom has significant severity if it substantially impacts (approximately a 50% reduction) on the patient’s life experience and activities. In assessing severity and impact, compare the patient’s activity level to their premorbid activity level. Establishing the severity ...
Living with Ulcerative Colitis
... No one knows exactly what causes ulcerative colitis. Also, no one can predict how the disease—once it is diagnosed—will affect a particular person. Some people go for years without having any symptoms, while others have more frequent flare-ups, or symptom attack, of their disease activity. However, o ...
... No one knows exactly what causes ulcerative colitis. Also, no one can predict how the disease—once it is diagnosed—will affect a particular person. Some people go for years without having any symptoms, while others have more frequent flare-ups, or symptom attack, of their disease activity. However, o ...
Review - American Physiological Society
... no reliable ameliorating treatment is available for such involvement, it frequently leads to severe respiratory disability and often death (8). The most prominent symptoms are tachypnea and exertional dyspnea, secondary to either pulmonary fibrosis or pulmonary hypertension. Many patients remain asy ...
... no reliable ameliorating treatment is available for such involvement, it frequently leads to severe respiratory disability and often death (8). The most prominent symptoms are tachypnea and exertional dyspnea, secondary to either pulmonary fibrosis or pulmonary hypertension. Many patients remain asy ...
Age-Related Macular Degeneration
... scientific data as interpreted by panels of knowledgeable health professionals. In some instances, such as when results of carefully conducted clinical trials are available, the data are particularly persuasive and provide clear guidance. In other instances, the panels have to rely on their collecti ...
... scientific data as interpreted by panels of knowledgeable health professionals. In some instances, such as when results of carefully conducted clinical trials are available, the data are particularly persuasive and provide clear guidance. In other instances, the panels have to rely on their collecti ...
Robert W. Sweetow, Ph.D. - The International Tinnitus Journal.
... It is difficult to state definitively whether the emotional status of tinnitus patients existed before the onset of tinnitus, or whether it resulted from the tinnitus. The hearing health care professional must be prepared to recognize when outside referral to a mental health professional is appropri ...
... It is difficult to state definitively whether the emotional status of tinnitus patients existed before the onset of tinnitus, or whether it resulted from the tinnitus. The hearing health care professional must be prepared to recognize when outside referral to a mental health professional is appropri ...
Imiquimod 5% cream for the treatment of actinic keratosis
... range from 11% to 25%, whereas in the whiteskinned population living in Australia, the incidence is estimated to range from 40% to 60%.4,5 Histologically and clinically, there is a continuum and a progression between AK and squamous cell carcinoma (SCC) that makes reliable clinical distinction betwe ...
... range from 11% to 25%, whereas in the whiteskinned population living in Australia, the incidence is estimated to range from 40% to 60%.4,5 Histologically and clinically, there is a continuum and a progression between AK and squamous cell carcinoma (SCC) that makes reliable clinical distinction betwe ...
Innovative Medicines Division
... Head-to-head superiority trials underway in three indications to potentially become standard of care • Most comprehensive head-to-head program to date in psoriasis, PsA and AS ...
... Head-to-head superiority trials underway in three indications to potentially become standard of care • Most comprehensive head-to-head program to date in psoriasis, PsA and AS ...
Clinical Signs of Gout
... attack is often dramatic and painful, it is usually selflimited and lasts only several days. After each attack, long asymptomatic intervals may occur, which are referred to as the intercritical period.8 This stage may last many years and, in some cases, patients have persistent hyperuricemia and low ...
... attack is often dramatic and painful, it is usually selflimited and lasts only several days. After each attack, long asymptomatic intervals may occur, which are referred to as the intercritical period.8 This stage may last many years and, in some cases, patients have persistent hyperuricemia and low ...
Prozac - Eli Lilly and Company
... Adult — Initiate PROZAC 20 mg/day, orally in the morning. Consider a dose increase after several weeks if insufficient clinical improvement is observed. The full therapeutic effect may be delayed until 5 weeks of treatment or longer. Administer doses above 20 mg/day once daily in the morning or twic ...
... Adult — Initiate PROZAC 20 mg/day, orally in the morning. Consider a dose increase after several weeks if insufficient clinical improvement is observed. The full therapeutic effect may be delayed until 5 weeks of treatment or longer. Administer doses above 20 mg/day once daily in the morning or twic ...
Efficacy of Human Immunoglobulin and Penicillin G in
... animals assigned to the various treatment groups (Table 1). Table 1 compares the overall mortality and bacterial clearance from blood and CSF among the six treatment groups. All animals receiving ISG alone died within 2 days of therapy. Otherwise, the mortality rates among the remaining five groups ...
... animals assigned to the various treatment groups (Table 1). Table 1 compares the overall mortality and bacterial clearance from blood and CSF among the six treatment groups. All animals receiving ISG alone died within 2 days of therapy. Otherwise, the mortality rates among the remaining five groups ...
Global Initiative for Chronic Obstructive Lung Disease
... Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality throughout the world. Much has been learned about COPD since the Global Initiative for Chronic Obstructive Lung Disease issued its first report, Global Strategy for the Diagnosis, Management, and Prevention of C ...
... Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality throughout the world. Much has been learned about COPD since the Global Initiative for Chronic Obstructive Lung Disease issued its first report, Global Strategy for the Diagnosis, Management, and Prevention of C ...
The Ocular Side-Effects of Vigabatrin
... Treatment dose and duration Several studies have not identified a relationship between the daily or cumulative dose of vigabatrin and the risk of VAVFC. It has therefore been postulated that the drug response is idiosyncratic in nature. By contrast other studies, with more precise data on dose and d ...
... Treatment dose and duration Several studies have not identified a relationship between the daily or cumulative dose of vigabatrin and the risk of VAVFC. It has therefore been postulated that the drug response is idiosyncratic in nature. By contrast other studies, with more precise data on dose and d ...
Premenstrual syndrome and premenstrual dysphoric disorder
... of psychosocial stressors and likely still benefit from charting and conservative interventions. ...
... of psychosocial stressors and likely still benefit from charting and conservative interventions. ...
Bleomycin PFI
... pulmonary fibrosis. Frequent chest X-rays (preferably weekly) are advisable and should be continued for up to 4 weeks after completion of a course of treatment. Pulmonary toxicity of Bleomycin is both dose-related and age-related when the total dose exceeds 400 units (USP) (approximately 225 units/m ...
... pulmonary fibrosis. Frequent chest X-rays (preferably weekly) are advisable and should be continued for up to 4 weeks after completion of a course of treatment. Pulmonary toxicity of Bleomycin is both dose-related and age-related when the total dose exceeds 400 units (USP) (approximately 225 units/m ...
Clinical guidelines for best practice management of acute and chronic whiplash-associated disorders
... Treatments that had evidence against their use, and treatments for which there was an absence of evidence, and were therefore not recommended on the basis of consensus, were grouped under the heading Treatments that should not be undertaken. The distinction between the latter two groups is made expl ...
... Treatments that had evidence against their use, and treatments for which there was an absence of evidence, and were therefore not recommended on the basis of consensus, were grouped under the heading Treatments that should not be undertaken. The distinction between the latter two groups is made expl ...
informe del instituto quintiles-ims: "outlook for global
... U.S. market growth will slow by half in 2016 to 6–7% from 12% in 2015, and is forecast to average 6–9% through 2021. This decline is a key driver of the overall global slowdown and has similar causes—the end of Hepatitis C-driven growth and the greater impact of patent expiries after a period with f ...
... U.S. market growth will slow by half in 2016 to 6–7% from 12% in 2015, and is forecast to average 6–9% through 2021. This decline is a key driver of the overall global slowdown and has similar causes—the end of Hepatitis C-driven growth and the greater impact of patent expiries after a period with f ...
Intergroup Study (EORTC 20051)
... H8+H9) (Ref. 12, Ref. 13, Ref. 14) We aim in this new trial at reducing treatment related toxicity especially long-term- in selected groups of patients who are “overtreated” with the current treatment standard. Patients who are cured of HL have a life-long increased risk of premature death as compar ...
... H8+H9) (Ref. 12, Ref. 13, Ref. 14) We aim in this new trial at reducing treatment related toxicity especially long-term- in selected groups of patients who are “overtreated” with the current treatment standard. Patients who are cured of HL have a life-long increased risk of premature death as compar ...
Management of multiple sclerosis
Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.