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Asthma: Multi-System Implications.
Asthma: Multi-System Implications.

... neurogenic, chemical, and pharmacologic factors that are associated with asthma are specific to each individual. They stimulate or trigger the immune system to release chemical mediators, which in turn cause constriction of the bronchial muscles, increased mucus production, and swelling of the mucou ...
Slide 1
Slide 1

AASLD PRACTICE GUIDELINE UPDATE Chronic Hepatitis B
AASLD PRACTICE GUIDELINE UPDATE Chronic Hepatitis B

... HBV is transmitted by perinatal, percutaneous, and sexual exposure, as well as by close person-to-person contact presumably by open cuts and sores, especially among children in hyperendemic areas.10 HBV can survive outside the body for prolonged periods.18,19 The risk of developing chronic HBV infec ...
Clinical characteristics and risk factors for mortality in Morganella
Clinical characteristics and risk factors for mortality in Morganella

... M. morganii from blood culture. Bacteremia was considered hospital-acquired if blood culture performed ≥72 h after admission was positive for M. morganii in a patient who was asymptomatic for bacteremia at admission, or if the M. morganii bacteremia had been acquired during stay at another hospital ...
Critical illness neuropathy and myopathy
Critical illness neuropathy and myopathy

... Critically ill patients in the intensive care unit (ICU) frequently develop severe muscle weakness independently of whether they suffer from primary neurological diseases. This becomes apparent, at the latest, when weaning from the ventilator proves impossible or difficult and if physical rehabilita ...
Electroconvulsive Therapy and Related Treatments
Electroconvulsive Therapy and Related Treatments

... been investigated in mixed-age samples, including the dexamethasone suppression test, the thyrotropin-releasing hormone test, and other neuroendocrine tests (Decina et al. 1987; Kamil and Joffe 1991; Kirkegaard et al. 1975; Krog-Meyer et al. 1984; Papakostas et al. 1981; Swartz 1993), as well as pol ...
1 Chiari Malformation: A Literature Review Jessica Heithoff
1 Chiari Malformation: A Literature Review Jessica Heithoff

... Conclusion Chiari Malformation findings are becoming more common as the use of diagnostic imaging has increased. Sagittal MRI images are used to help diagnose and classify the different types of Chiari Malformations. Researchers are working to narrow down the genetic aspects that could possibly be t ...
Advances in the diagnosis and management REVIEW
Advances in the diagnosis and management REVIEW

... disease in others, the threshold of what constitutes pathological aspiration in a given individual may vary. Determining whether aspiration is a significant cause of respiratory disease can thus be challenging. There are no gold-standard diagnostic tests for CPA. Currently, the diagnosis of aspirati ...
1 Chiari Malformation: A Literature Review Jessica Heithoff
1 Chiari Malformation: A Literature Review Jessica Heithoff

... Conclusion Chiari Malformation findings are becoming more common as the use of diagnostic imaging has increased. Sagittal MRI images are used to help diagnose and classify the different types of Chiari Malformations. Researchers are working to narrow down the genetic aspects that could possibly be t ...
Full Article – PDF
Full Article – PDF

... and creatinine levels (in 50 to 75% of cases due to ureteral entrapment), and polyclonal hypergammaglobulinemia (and hyper IgG4 [16]). Imaging may include intravenous pyelography (IVP), showing medially deviated and narrowed ureters, with proximal dilatation and various degrees of hydronephrosis. Th ...
Greater first year effectiveness drives favorable cost
Greater first year effectiveness drives favorable cost

... alendronate. Large head-to-head randomized clinical trials comparing fracture outcomes between risedronate and alendronate treatment are not available; as such, costeffectiveness analyses have relied on linking data from clinical trials through placebo arms. However, this method has had two main wea ...
Immune-Mediated Adverse Reactions Management Guide
Immune-Mediated Adverse Reactions Management Guide

... WARNING: IMMUNE-MEDIATED ADVERSE REACTIONS YERVOY can result in severe and fatal immune-mediated adverse reactions. These immune-mediated reactions may involve any organ system; however, the most common severe immune-mediated adverse reactions are enterocolitis, hepatitis, dermatitis (including toxi ...
Neoral PI approved 21.05.12
Neoral PI approved 21.05.12

... performed to examine relapse rates following cyclosporin withdrawal or the effects of longterm therapy and different dosing strategies. In one of these studies (SIM SF04), 5 mg/kg per day of the drug was given for 6 weeks, then the relapse rates were observed over a further 6 weeks; patients who rel ...
digitalis_toxcicty
digitalis_toxcicty

Clinical Practice Guideline - Lymphoma
Clinical Practice Guideline - Lymphoma

EMEDICINE SPECIALTIES > DERMATOLOGY > DISEASES OF THE ADNEXA ALOPECIA AREATA
EMEDICINE SPECIALTIES > DERMATOLOGY > DISEASES OF THE ADNEXA ALOPECIA AREATA

... Much evidence supports the hypothesis that alopecia areata is an autoimmune condition. The process appears to be T-cell mediated, but antibodies directed to hair follicle structures also have been found with increased frequency in alopecia areata patients compared with control subjects. Using immun ...
Preview the material
Preview the material

... organ system, and the pathogenesis of SLE is a complex, and incompletely understood process involving genetic, environmental, and immunologic factors. Symptomatic therapy for SLE can be very effective and advances in treatment have dramatically increased survival rates. However, there is no cure and ...
Trigeminal Neuralgia - American Academy of Family Physicians
Trigeminal Neuralgia - American Academy of Family Physicians

... multiple sclerosis or by tumors arising near the trigeminal smaller studies or case reports include phenytoin (Dilannerve root. A history of previous neurologic symptoms tin), lamotrigine (Lamictal), gabapentin (Neurontin), and typical findings on MRI assist with the diagnosis of topiramate (Topamax) ...
Chronic plaque psoriasis?
Chronic plaque psoriasis?

... weekly is effective for generalized disease. It is often considered in patients for whom narrowband UVB therapy is ineffective. However, many PUVA treatments are required, necessitating frequent office visits, and it may be associated with phototoxicity, such as erythema and blistering, and increase ...
Alzheimer`s Dementia
Alzheimer`s Dementia

... Upon discontinuation of treatment, a gradual abatement of the beneficial effects of donepezil hydrochloride is seen. Patients with renal or hepatic impairment A similar dose schedule can be followed for patients with renal impairment, as clearance of donepezil hydrochloride is not affected by this c ...
Syndrome de Fatigue Chronique: diagnostic, traitement et
Syndrome de Fatigue Chronique: diagnostic, traitement et

... La reproduction partielle de ce document est autorisée à condition que la source soit mentionnée. Ce document est disponible en téléchargement sur le site Web du Centre fédéral d’expertise des soins de santé. Comment citer ce rapport ? Stordeur S, Thiry N, Eyssen M. Syndrome de Fatigue Chronique : d ...
rch - Therapeutic Goods Administration
rch - Therapeutic Goods Administration

... statins and other lipid lowering therapies such as LDL apheresis and partial ileal bypass.1 There may be differences in Asian and Caucasian populations in the phenotypes that specific mutations cause. PCSK9 gain-of function mutations, such as the D374Y mutation, decrease the number of LDL receptors ...
Cutaneous Lupus Erythematosus
Cutaneous Lupus Erythematosus

...  Common in acute cutaneous LE (occurs in 20-60% of patients with LE)  Begins on malar area and bridge of nose, classically associated with edema (can be severe)  Nasolabial folds are characteristically spared  May begin as macules and/or papules the may become confluent and hyperkeratotic  Ears ...
L-Tyrosine Monograph - Alternative Medicine Review
L-Tyrosine Monograph - Alternative Medicine Review

... double-blind, placebo-controlled trial involving 14 patients suffering from major depression (five or more symptoms of depression present for at least two weeks) of at least moderate severity. Six patients received 100 mg/kg oral tyrosine daily and eight received placebo for four weeks. Four of six ...
PRESCRIBING INFORMATION ATIVAN
PRESCRIBING INFORMATION ATIVAN

... obstruction may occur and be fatal. Patients who develop angioedema after treatment with a benzodiazepine should not be rechallenged with the drug. Ativan (lorazepam) is not recommended for the use in depressive neurosis or in psychotic reactions. Because of the lack of sufficient clinical experienc ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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