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NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines
NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines

... age is a poor surrogate for fitness for therapy. Patients should be evaluated on an individual basis, including for the following factors: end-organ reserve, end-organ dysfunction, and performance status. l All ALL treatment regimens include CNS prophylaxis. m See Principles of Chemotherapy (ALL-D). ...
1 HIGHLIGHTS OF PRESCRIBING INFORMATION
1 HIGHLIGHTS OF PRESCRIBING INFORMATION

... inhibiting the progression of structural damage, and improving physical function in patients with psoriatic arthritis. 1.8 Plaque Psoriasis REMICADE is indicated for the treatment of adult patients with chronic severe (i.e., extensive and/or disabling) plaque psoriasis who are candidates for system ...
(95% CI) OR
(95% CI) OR

... gastroesophageal reflux, osteoporosis with prolonged use, osteonecrosis even with a single dose, adrenal insufficiency, increased risk of mild and serious infections and malignancy, neurocognitive events including depression and psychosis, ...
Osteopathic Treatment of Female Incontinence
Osteopathic Treatment of Female Incontinence

... The bladder empties itself by reflex, without the individual having the urge to urinate. In most cases however, there remains additional residual urine indicating an incomplete drainage of the bladder. Overflow incontinence occurs when the pressure in the overfilled bladder is higher than the closin ...
Generalized Pustular Psoriasis of Zambusch: Case Report of Successful
Generalized Pustular Psoriasis of Zambusch: Case Report of Successful

... et al18 retrospectively reviewed 12 patients with psoriasis onset or exacerbation while on anti–TNF-a therapy; they found that skin lesions often developed within the first few months of treatment and were more common in patients with a history of psoriasis. Palmoplantar pustular psoriasis was a com ...
RES-ML2-COPD_FINAL
RES-ML2-COPD_FINAL

... Initiative for Chronic Obstructive Lung Disease (GOLD) stage 1 or stage 2, with progression to GOLD 3 or 4 with severe failure) ...
Integrating Cryptococcal Antigen Screening and Pre
Integrating Cryptococcal Antigen Screening and Pre

... 20% and 39% in a tertiary care referral hospital despite access to ART,8,9 with only 40% alive after 6 months.10 The experience in South Africa has been similar, with in-hospital mortality near 30%, and 6-month survival of 40%–60%.1,11 Outcomes in routine clinical practice are likely substantially w ...
Biomechanical aspects of external root resorption in orthodontic
Biomechanical aspects of external root resorption in orthodontic

... only a few teeth. The number increase significantly after 6 months. To monitor apical root resorption the standard procedure is a radiographic examination after 6 months of treatment. In teeth with enhanced risk, such as teeth with blunt and pipette-shaped apices, a 3-month radiographic control foll ...
In July 2004, The Training Program Director`s Core Curriculum and
In July 2004, The Training Program Director`s Core Curriculum and

...  The Reading List Subcommittee  The In-Training Examination Subcommittee. This document provides a framework for training programs to design an individualized course of study that supplements the diverse strengths and weaknesses of each fellowship training program and faculty. It is updated every ...
Product Monograph Template - Standard - GlaxoSmithKline
Product Monograph Template - Standard - GlaxoSmithKline

... may experience worsening of their depressive symptoms and/or the emergence of suicidal ideation and behaviours (suicidality) whether or not they are taking medications for bipolar disorder, including lamotrigine. Suicidal ideation and behaviour have been reported in patients treated with antiepilept ...
symptom assessment and management in patients with heart failure
symptom assessment and management in patients with heart failure

... Patients with heart failure (HF) must monitor and recognize escalating symptoms to manage worsening HF in a timely manner. However, routine symptom monitoring is not commonly performed by this population. Providing a symptom diary along with an education and counseling session may help HF patients p ...
BCG plus Interferon-alpha for Superficial Bladder Cancer
BCG plus Interferon-alpha for Superficial Bladder Cancer

... systemic steroids (e.g. prednisone 40 mg/day) may be life-saving in cases of frank BCG sepsis. Antibiotics must accompany steroid use. ...
alzheimer`s disease - Innovative Educational Services
alzheimer`s disease - Innovative Educational Services

... helped explain some of the variation in the age at which the disease develops. Scientists are continuing this research through the Dominantly Inherited Alzheimer Network (DIAN), an international partnership to study families with a genetic mutation that causes early-onset Alzheimer's disease. By obs ...
Communications - Canadian Rheumatology Association
Communications - Canadian Rheumatology Association

... rheumatologists to ensure that patients taking potentially teratogenic medications do not become ...
Full-Text PDF
Full-Text PDF

... recognized by distinct receptors. The effector responses triggered lead to a chronic tissue inflammation. DsDNA autoantibodies are the most studied as well as the first in being characterized for its pathogenic role in Lupus nephritis. However, others are of growing interest since they have been ass ...
Frequently-Asked Questions about LDN
Frequently-Asked Questions about LDN

... clinical studies with low dose naltrexone in normal volunteers, HIV positive, Multiple Sclerosis, Autism, Fibromyalgia, Diabetes, and cancer patients showed no major toxicity Current treatments used to prevent the development of immunodeficiency in individuals with autoimmune disease, Crohn’s Diseas ...
HIGHLIGHTS OF PRESCRIBING INFORMATION ------------------------------- CONTRAINDICATIONS ------------------------------
HIGHLIGHTS OF PRESCRIBING INFORMATION ------------------------------- CONTRAINDICATIONS ------------------------------

... be carefully monitored during COUMADIN therapy. Determine the INR daily after the administration of the initial dose until INR results stabilize in the therapeutic range. After stabilization, maintain dosing within the therapeutic range by performing periodic INRs. The frequency of performing INR sh ...
Lower extremity lymphedema
Lower extremity lymphedema

... looking for the presence of microfilariae. Antigen testing by immunochromatographic card test (Binax) or enzyme-linked immunosorbent assay (TropBio) is more sensitive than microfilariae detection; these tests can use blood collected during the day or night.16 In addition to a thorough history and ph ...
Diagnosis and treatment of lupus nephritis
Diagnosis and treatment of lupus nephritis

... individualised based on the characteristics of each patient and their current stage of disease, taking into account that the patient will require life-long follow-up. There is some debate regarding how to measure proteinuria. Although the gold standard is 24-hour urine samples, the protein/creatinin ...
ADULT SEPSIS SCREEN AND TREATMENT ALGORITHM BAYLOR
ADULT SEPSIS SCREEN AND TREATMENT ALGORITHM BAYLOR

... Special handling was required to compensate and expedite these specific tests within our ED. Finally, it seemed that EM provider and ED nursing education and feedback was an essential component of our intervention. This alone represents the single greatest labor intensive aspect of our implementatio ...
Lichen planus and its management
Lichen planus and its management

... taper). Other treatments that have been tried (unlicensed indications) include the topical calcineurin inhibitors tacrolimus and pimecrolimus, ciclosporin (1–6mg/kg/day for several months2), acitretin (30mg/day for eight weeks2) and methotrexate (1–15mg/week for up to 17 months3). Treatment with ult ...
Exelon® Patch 5
Exelon® Patch 5

... more intense local reaction (e.g. increasing erythema, edema, papules, vesicles) and if symptoms do not significantly improve within 48 hours after patch removal. In these cases, treatment should be discontinued (see section CONTRAINDICATIONS). In patients who develop application site reactions sugg ...
RCSLT Project1 - Royal College of Speech and Language Therapists
RCSLT Project1 - Royal College of Speech and Language Therapists

... Furthermore, aspiration pneumonia is a leading cause of death in nursing homes. It has been reported that between 35-85% of people are malnourished in longstay institutions such as nursing and residential homes. As well as being an alarming symptom, swallowing difficulties in the elderly lead to phy ...
CLINICAL AND MYCOLOGICAL STUDY OF DERMATOPHYTOSIS IN JAIPUR (INDIA)  Research Article   DR. RICHA SHARMA
CLINICAL AND MYCOLOGICAL STUDY OF DERMATOPHYTOSIS IN JAIPUR (INDIA)  Research Article   DR. RICHA SHARMA

LAMICTAL Product Monograph
LAMICTAL Product Monograph

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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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