Chromatin as a target antigen in human and murine lupus nephritis
... autoantibodies possess the potential to induce nephritis, the most serious complication in SLE [23,24]. The aetiology of SLE is not fully understood, but there are recent advances in its understanding. For example, there is growing interest in regulatory RNA molecules in SLE. miRNAs belong to a fami ...
... autoantibodies possess the potential to induce nephritis, the most serious complication in SLE [23,24]. The aetiology of SLE is not fully understood, but there are recent advances in its understanding. For example, there is growing interest in regulatory RNA molecules in SLE. miRNAs belong to a fami ...
Ophthalmology and Eye Diseases Review of Azithromycin
... showed peak drug concentrations in the tear film, cornea, conjunctiva and eyelids were higher when azithromycin was used with polycarbophil rather than without as demonstrated by the area under the curve (AUC). The sustained effect of azithromycin with polycarbophil after discontinuation of the medi ...
... showed peak drug concentrations in the tear film, cornea, conjunctiva and eyelids were higher when azithromycin was used with polycarbophil rather than without as demonstrated by the area under the curve (AUC). The sustained effect of azithromycin with polycarbophil after discontinuation of the medi ...
Brainstorm Reference Guide - American Headache Society
... 40 and then declining over the next few decades. Since these changes correspond with the female reproductive life cycle, it is reasonable to suppose that the sex steroids (such as estrogen and progesterone) are involved, but a causal relationship has not been defined. Other agerelated metabolic chang ...
... 40 and then declining over the next few decades. Since these changes correspond with the female reproductive life cycle, it is reasonable to suppose that the sex steroids (such as estrogen and progesterone) are involved, but a causal relationship has not been defined. Other agerelated metabolic chang ...
A Prospective Study of the Risk Factors Associated with Failure of
... proved the effectiveness of 1-mm-diameter miniscrews as anchors for orthodontic intrusion. Miniscrews 2 mm in diameter have been successfully used as anchorage for orthodontic patients.2,3,5 However, most of the previous accounts concerning the use of mini-implants for orthodontic purposes were in t ...
... proved the effectiveness of 1-mm-diameter miniscrews as anchors for orthodontic intrusion. Miniscrews 2 mm in diameter have been successfully used as anchorage for orthodontic patients.2,3,5 However, most of the previous accounts concerning the use of mini-implants for orthodontic purposes were in t ...
Clinical evaluation of Chronic HCV Infected Persons
... * For persons who might have been exposed to HCV within the past 6 months, testing for HCV RNA or follow-up testing for HCV antibody is recommended. For persons who are immunocompromised, testing for HCV RNA can be considered. ** To differentiate past, resolved HCV infection from biologic false posi ...
... * For persons who might have been exposed to HCV within the past 6 months, testing for HCV RNA or follow-up testing for HCV antibody is recommended. For persons who are immunocompromised, testing for HCV RNA can be considered. ** To differentiate past, resolved HCV infection from biologic false posi ...
ABILIFY® (aripiprazole)
... The recommended target dose of ABILIFY is 10 mg/day. Aripiprazole was studied in adolescent patients 13 to 17 years of age with schizophrenia at daily doses of 10 mg and 30 mg. The starting daily dose of the tablet formulation in these patients was 2 mg, which was titrated to 5 mg after 2 days and t ...
... The recommended target dose of ABILIFY is 10 mg/day. Aripiprazole was studied in adolescent patients 13 to 17 years of age with schizophrenia at daily doses of 10 mg and 30 mg. The starting daily dose of the tablet formulation in these patients was 2 mg, which was titrated to 5 mg after 2 days and t ...
Ginkgo Biloba Extract: A Review
... (one of the presumed active ingredients). In a few studies, larger doses (up to 320 mg/day) were used. Products made from the whole leaf of the ginkgo tree are probably not as effective as the standardized extract. The beneficial effects of ginkgo are sometimes seen as early as one or two weeks afte ...
... (one of the presumed active ingredients). In a few studies, larger doses (up to 320 mg/day) were used. Products made from the whole leaf of the ginkgo tree are probably not as effective as the standardized extract. The beneficial effects of ginkgo are sometimes seen as early as one or two weeks afte ...
Inhalant-allergens
... Local reactions range on a spectrum of pain and induration Systemic reactions usually manifest as exacerbation of the patients symptoms Treatment consists of antihistamines and reassurance, with steroids for more severe symptoms. ...
... Local reactions range on a spectrum of pain and induration Systemic reactions usually manifest as exacerbation of the patients symptoms Treatment consists of antihistamines and reassurance, with steroids for more severe symptoms. ...
Anaphylaxis - Repid Recognition and Treatment
... ● ACE inhibitors are of particular importance in regards to patients who have experienced anaphylaxis to Hymenoptera venom [44,45]. They not only block the effect of angiotensin, a compensatory response, but also block the degradation of kinins which are active in the production of symptoms and sign ...
... ● ACE inhibitors are of particular importance in regards to patients who have experienced anaphylaxis to Hymenoptera venom [44,45]. They not only block the effect of angiotensin, a compensatory response, but also block the degradation of kinins which are active in the production of symptoms and sign ...
Drug Allergy: An Updated Practice Parameter
... allergy is defined as an immunologically mediated response to a pharmaceutical and/or formulation (excipient) agent in a sensitized person. The implication is that drug allergy does not simply include only IgE-mediated reactions. Another significant change is the introduction of the new term induct ...
... allergy is defined as an immunologically mediated response to a pharmaceutical and/or formulation (excipient) agent in a sensitized person. The implication is that drug allergy does not simply include only IgE-mediated reactions. Another significant change is the introduction of the new term induct ...
Lamotrigin Actavis tablet ENG SmPC
... response. During the pill-free week, a two-fold increase in lamotrigine levels has been observed. Doserelated adverse events cannot be excluded. Therefore, consideration should be given to using contraception without a pill-free week, as first-line therapy (for example, continuous hormonal contrace ...
... response. During the pill-free week, a two-fold increase in lamotrigine levels has been observed. Doserelated adverse events cannot be excluded. Therefore, consideration should be given to using contraception without a pill-free week, as first-line therapy (for example, continuous hormonal contrace ...
exercise rehabilitation in the non-operative management of rotator
... were commonly located more posterior than originally thought, approximately 15mm posterior to the biceps tendon. This suggests that most degenerative cuff tears initiate from a region near the junction of the supraspinatus and infraspinatus tendons. Superior rotator cuff tears not involving the cabl ...
... were commonly located more posterior than originally thought, approximately 15mm posterior to the biceps tendon. This suggests that most degenerative cuff tears initiate from a region near the junction of the supraspinatus and infraspinatus tendons. Superior rotator cuff tears not involving the cabl ...
Product Monograph
... and monitored regularly during treatment. Patients should be told to consult their doctors if they have symptoms associated with acute severe hypertension, such as headache (particularly in the back of head/neck when waking up), stronger heart beat and possibly more rapid, palpitations, dizziness, e ...
... and monitored regularly during treatment. Patients should be told to consult their doctors if they have symptoms associated with acute severe hypertension, such as headache (particularly in the back of head/neck when waking up), stronger heart beat and possibly more rapid, palpitations, dizziness, e ...
112196 Primary Biliary Cirrhosis
... and is infiltrated by lymphocytes and fragments of lymphocytes. The epithelial cells are damaged and are missing from one quadrant of the duct, which has presumably been totally destroyed. The cells surrounding the bile duct are primarily lymphocytes, but there are also larger mononuclear cells and ...
... and is infiltrated by lymphocytes and fragments of lymphocytes. The epithelial cells are damaged and are missing from one quadrant of the duct, which has presumably been totally destroyed. The cells surrounding the bile duct are primarily lymphocytes, but there are also larger mononuclear cells and ...
ANTIMICROBIAL TREATMENT OF BACTERIAL CNS INFECTIONS
... diagnosis was defined by a CSF white blood cell count of over 1,000 cells per mm 3 and/or more than 80% polymorphonuclear cells, the CSF culture was positive for 85% of cases in the absence of prior antibiotic ...
... diagnosis was defined by a CSF white blood cell count of over 1,000 cells per mm 3 and/or more than 80% polymorphonuclear cells, the CSF culture was positive for 85% of cases in the absence of prior antibiotic ...
Treatment of Patients With Eating Disorders
... circumstances rather than simply rely on one or more physical parameters, such as weight [I]. Weight in relation to estimated individually healthy weight, the rate of weight loss, cardiac function, and metabolic status are the most important physical parameters to be considered when choosing a treat ...
... circumstances rather than simply rely on one or more physical parameters, such as weight [I]. Weight in relation to estimated individually healthy weight, the rate of weight loss, cardiac function, and metabolic status are the most important physical parameters to be considered when choosing a treat ...
Prevention and Treatment of Cancer-Related Infections
... k Consider antifungal prophylaxis in all patients with GVHD receiving the clearance of several agents used to treat cancer. n A lipid formulation is generally preferred based on less toxicity. immunosuppressive therapy. Note: All recommendations are category 2A unless otherwise indicated. Clinical T ...
... k Consider antifungal prophylaxis in all patients with GVHD receiving the clearance of several agents used to treat cancer. n A lipid formulation is generally preferred based on less toxicity. immunosuppressive therapy. Note: All recommendations are category 2A unless otherwise indicated. Clinical T ...
lewy_body_dementia
... activity. Being outdoors and exercising is vital for the health and state of mind—of both of you. Strengthen senses. Have a doctor evaluate each the patient’s five senses in order to identify and treat any abnormalities. Then ask about exercises to improve them. Make behavioral changes. To help mini ...
... activity. Being outdoors and exercising is vital for the health and state of mind—of both of you. Strengthen senses. Have a doctor evaluate each the patient’s five senses in order to identify and treat any abnormalities. Then ask about exercises to improve them. Make behavioral changes. To help mini ...
Beth A. Drolet, Peter C. Frommelt, Sarah L. Chamlin, Anita... Bauman, Yvonne E. Chiu, Robert H. Chun, Maria C. Garzon,... Initiation and Use of Propranolol for Infantile Hemangioma: Report of... Consensus Conference
... Infantile hemangiomas (IHs) are common neoplasms composed of proliferating endothelial-like cells. Despite the relative frequency of IH and the potential severity of complications, there are currently no uniform guidelines for treatment. Although propranolol has rapidly been adopted, there is signifi ...
... Infantile hemangiomas (IHs) are common neoplasms composed of proliferating endothelial-like cells. Despite the relative frequency of IH and the potential severity of complications, there are currently no uniform guidelines for treatment. Although propranolol has rapidly been adopted, there is signifi ...
(ezetimibe, rosuvastatin (as calcium)
... Renal Insufficiency Ezetimibe After a single 10 mg dose of ezetimibe in patients with severe renal disease (n=8; mean CrCl ≤ 30 mL/min/1.73 m2), the mean AUC for total ezetimibe was increased approximately 1.5-fold, compared to healthy subjects (n=9). This result is not considered clinically signifi ...
... Renal Insufficiency Ezetimibe After a single 10 mg dose of ezetimibe in patients with severe renal disease (n=8; mean CrCl ≤ 30 mL/min/1.73 m2), the mean AUC for total ezetimibe was increased approximately 1.5-fold, compared to healthy subjects (n=9). This result is not considered clinically signifi ...
peripheral neuropathy
... Quite frequently, podiatrists are faced with difficult patients without an obvious diagnosis. These are patients who may have seen several other specialists who were also stumped by the patient's disease. Often this type of patient involves laboratory testing which includes nerve conduction studies ...
... Quite frequently, podiatrists are faced with difficult patients without an obvious diagnosis. These are patients who may have seen several other specialists who were also stumped by the patient's disease. Often this type of patient involves laboratory testing which includes nerve conduction studies ...
KDIGO Clinical Practice Guideline for the Management of Blood Pressure
... the recommended course of action and only a small proportion would not. ...
... the recommended course of action and only a small proportion would not. ...
Product Information for Rosuzet Composite Pack (ezetimibe
... Renal Insufficiency Ezetimibe After a single 10 mg dose of ezetimibe in patients with severe renal disease (n=8; mean CrCl ≤ 30 mL/min/1.73 m2), the mean AUC for total ezetimibe was increased approximately 1.5-fold, compared to healthy subjects (n=9). This result is not considered clinically signifi ...
... Renal Insufficiency Ezetimibe After a single 10 mg dose of ezetimibe in patients with severe renal disease (n=8; mean CrCl ≤ 30 mL/min/1.73 m2), the mean AUC for total ezetimibe was increased approximately 1.5-fold, compared to healthy subjects (n=9). This result is not considered clinically signifi ...
depo-provera
... Incident Rate Ratio (IRR) for any fracture during the follow-up period (mean = 5.5 years) was 1.41 (95% CI 1.35, 1.47). Among the sub-cohort with data before and after first reported contraceptive treatment (N=166,367), comparisons were made for the follow-up period and also for the 6-month period p ...
... Incident Rate Ratio (IRR) for any fracture during the follow-up period (mean = 5.5 years) was 1.41 (95% CI 1.35, 1.47). Among the sub-cohort with data before and after first reported contraceptive treatment (N=166,367), comparisons were made for the follow-up period and also for the 6-month period p ...
Management of multiple sclerosis
Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.