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Susceptibility Weighted Imaging (SWI): Contributions to Multiple
Susceptibility Weighted Imaging (SWI): Contributions to Multiple

... Multiple sclerosis is the most common neurological disease of young adult caucasian and the most common cause of neurological disability in young adults. It is an inflammatory and demyelinating disease characterized by inflammation, demyelination plaques, axonal loss and gliosis. MRI is nowadays a m ...
Sphincter of Oddi dysfunction
Sphincter of Oddi dysfunction

... disruption in the flow of digestive juices through the sphincter, causing them to back-up in the bile duct system. Sometimes, this back flow can lead to blockages in the bile duct system or the pancreas, which can cause pancreatitis (inflammation of the pancreas) or abnormal blood tests (liver funct ...
IACFS/ME Conference 2014 Summary
IACFS/ME Conference 2014 Summary

... (Salt Lake City, USA). She described O.I. as treatable with midodrine and there are 2 FDA trials happening. Hours of vertical activity (HVA) was used as a measure to assess effectiveness. A pilot study of 23 patients was undertaken, but 12 never started the medication, 5 did not continue (lack of co ...
CCC Course Portfolio
CCC Course Portfolio

... importance of close collaboration and team work with other members of the dental team and medical colleagues when treating patients, with periodontitis and know risk factors for periodontal disease. 3- They will have an understanding how the periodontal infections can affect the systemic health and ...
Orthognathic Treatment (Treatment of Dentofacial/Jaw Deformity)
Orthognathic Treatment (Treatment of Dentofacial/Jaw Deformity)

... The aforementioned patients commonly have dental malocclusions that cannot be managed by orthodontic treatment alone. All of these conditions are relatively uncommon but can have a devastating effect on patients in terms of function and integration in society. Although the majority of patients who p ...
ID_3859_Viral hepatitis-AIDS-Infectiou_English_sem_10
ID_3859_Viral hepatitis-AIDS-Infectiou_English_sem_10

... That characteristic of a partial answer of interferon therapy are all, except. Disappearance of markers of viral replication Normalization of activity of ALaT is upon completion of course of therapy Disappearance of icterus Normalization the state of patient Normalization of the size of liver That c ...
Chapter 25 – Dementia
Chapter 25 – Dementia

... more coarse in their display of emotions, and are less spontaneous. Some of these symptoms may mimic those of depression, but more often they occur in the absence of a clearly depressed mood or with thoughts of worthlessness, hopelessness, or guilt. Depressed mood may be evident at some time during ...
Pantoprazol Bluefish 20 mg gastro
Pantoprazol Bluefish 20 mg gastro

... has been achieved, reoccurring symptoms can be controlled using an on-demand regimen of 20 mg once daily, when required. A switch to continuous therapy may be considered in case satisfactory symptom control cannot be maintained with on-demand treatment. Long-term management and prevention of relapse ...
Biologic agents in psoriasis
Biologic agents in psoriasis

... reduction from baseline 2 weeks after the last dose, 79% maintain at least a 25% reduction in PASI during the 12week follow-up period.7 Adverse events reported from clinical trials include headache, pruritus, infection, rhinitis, injection site pain and injection site inflammation.7,9,10 The trials ...
Drug-induced  lung  disease:  1990  review REVIEW
Drug-induced lung disease: 1990 review REVIEW

... than 30 mg per 100 ml [36], pulmonary oedema was present in the oldest eight patients, in all smokers and in patients chronically receiving salicylate derivatives. Neurological abnormalities, proteinuria and a salicylate serum concentration higher than 40 mg per 100 ml were often present. The severi ...
Successful Metronidazole Desensitization Using Modified Oral
Successful Metronidazole Desensitization Using Modified Oral

... have been described, including one intravenous3 and two oral protocols [4,5]. In 2008, the Centers for Disease Control and Prevention published a study documenting a total of 127 patients with suspected metronidazole hypersensitivity, among whom 15 patients underwent metronidazole desensitization2. ...
The Diagnosis, Staging, and Treatment Options for Mycosis Fungoides
The Diagnosis, Staging, and Treatment Options for Mycosis Fungoides

... to 60 years). Children and adolescents are rarely affected. Approximately 1,000 new cases are diagnosed each year in the United States.12 The course of MF is usually indolent, with slow progression over years to decades, but it can be unpredictable. It usually demonstrates epidermotropism by involvi ...
The role of penicillin in benign skin rashes in childhood
The role of penicillin in benign skin rashes in childhood

... antibiotics, with somewhere between 3.6 g and 23 g per 1000 people per day prescribed in Europe.1 In children treated with b-lactams, skin rashes, mostly described as maculopapular or urticarial, are frequently reported by primary care physicians.2 Such rashes are frequently assumed to be a drug-rel ...
Symptomatic Arnold-Chiari malformation and cranial nerve
Symptomatic Arnold-Chiari malformation and cranial nerve

... health. As AK has grown and branched into so many areas within the healing arts, it has become apparent that many mental and emotional problems are due to physiologic dysfunction. When the body is returned to normal function, the mental or emotional problem is often eliminated or the patient is bett ...
PHENTERMINE HYDROCHLORIDE TABLETS USP, 37.5 mg CIV
PHENTERMINE HYDROCHLORIDE TABLETS USP, 37.5 mg CIV

... Phentermine hydrochloride is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with ...
Diagnosis and management of peripheral arterial disease. (SIGN
Diagnosis and management of peripheral arterial disease. (SIGN

... treatment has often been considered difficult because of concerns that antihypertensives, especially beta blockers, may have adverse effects on PAD due to possible drug induced peripheral vasoconstriction leading to further ischaemia in the leg. In a Cochrane systematic review of the treatment of hy ...
A trial of beclomethasone/formoterol in COPD using EXACT-PRO to measure exacerbations
A trial of beclomethasone/formoterol in COPD using EXACT-PRO to measure exacerbations

... most risk of future exacerbations. The recruitment approach employed in the stud ...
ARVO 2016 Annual Meeting Abstracts 515 Neuro
ARVO 2016 Annual Meeting Abstracts 515 Neuro

... Washington Hospital Center, The Plains, VA. Purpose: The debate over the need for MRI neuroimaging in the initial workup of acute oculomotor mononeuropathies is ongoing. While most cases are due to microvascular ischemia, studies have demonstrated that 1-15% are due to intracranial neoplasm, stroke, ...
English Edition, 2008
English Edition, 2008

... This allows one practitioner to apply a traditional TCM approach for use in diagnosis and treatment, while a second utilizes the principles of "Shanghanlun (On Cold Damage)" to construct a new theory, a third incorporates the principles of constitutional medicine in clinical practice, and a fourth p ...
Multiple Sclerosis: New perspectives on the patient journey
Multiple Sclerosis: New perspectives on the patient journey

... 570,000 people in the United States have MS.2,3 The majority of patients are diagnosed between the ages of 20 and 50 years, during their peak working years.4 Relapsing-remitting multiple sclerosis (RRMS) comprises the most common initial course of clinical progression, which is highly variable and u ...
Trichuris suis ova: Testing a helminth
Trichuris suis ova: Testing a helminth

... showed that current parasitic infection was statistically significantly associated with a reduced risk of skin sensitization to allergens (odds ratio, 0.69; 95% CI, 0.60-0.79; P <.01).9 Although this analysis shows a significant risk reduction, it relies on allergen skin reactivity, which is poorly ...
Drug-Induced Pulmonary Diseases
Drug-Induced Pulmonary Diseases

... in critically ill patients who are receiving neuromuscular blockers 1.2% of patients experiencing adverse drug reactions. In a recent continuously for more than 2 days to facilitate mechanical ventiretrospective analysis of clinical case series in France, 898 patients lation.7,8 This has resulted in ...
Prognostic Factors and Clinical Features of Non
Prognostic Factors and Clinical Features of Non

... a 2,900-bed tertiary referral medical center and has specialized units for solid organ and bone marrow transplantation, cardiac monitoring, burns and intensive care units. The medical records of eligible patients were reviewed, including their demographic characteristics, underlying diseases, clinic ...


... seems likely that inhaled steroids, by acting at the surface of the airway, have an effect that can be achieved only by large doses of oral steroids [21]. Thus, unless adequate inhaled forms of the drugs are reaching the airways, SRA cannot be established. There are many reasons why sufficient drug ...
Quality Measures Redux
Quality Measures Redux

... The make-up of the committee to determine these standards is overly weighted by “Epilepsy Specialists” (fourteen of these). I think the views of general, practicing neurologists should have been taken into account when a document of this nature is developed. Despite the inclusion of various imaging ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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