tecentriq® dosing and administration guide
... This indication is approved under accelerated approval based on tumor response rate and durability of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials. Metastatic non-small cell lung cancer TECENTRIQ is in ...
... This indication is approved under accelerated approval based on tumor response rate and durability of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials. Metastatic non-small cell lung cancer TECENTRIQ is in ...
PrDIANE®-35
... has been reported. Hepatic nodules (adenoma and focal nodular hyperplasia) have been reported, particularly in long-term users of estrogen/progestogen combinations. Although these lesions are uncommon, they have caused fatal intra-abdominal hemorrhage and should be considered in women presenting wit ...
... has been reported. Hepatic nodules (adenoma and focal nodular hyperplasia) have been reported, particularly in long-term users of estrogen/progestogen combinations. Although these lesions are uncommon, they have caused fatal intra-abdominal hemorrhage and should be considered in women presenting wit ...
Surgical Treatment of Mandibular Fracture without Intermaxillary
... when the dental arch was maintained in such a case like an isolated unilateral angle fracture, open reduction and internal fixation without intermaxillary fixation (IMF) brought satisfactory results (2-3). We propose that anatomical reduction and rigid fixation without IMF can provide secure immobil ...
... when the dental arch was maintained in such a case like an isolated unilateral angle fracture, open reduction and internal fixation without intermaxillary fixation (IMF) brought satisfactory results (2-3). We propose that anatomical reduction and rigid fixation without IMF can provide secure immobil ...
------------------RECENT MAJOR CHANGES
... Study 1, conducted by the National Cancer Institute (NCI), enrolled 184 patients; safety information is available for 149 patients. VORAXAZE was given at a dose of 50 Units/kg as an intravenous injection over 5 minutes. Patients with pre-VORAXAZE methotrexate concentrations >100 μmol/L were to recei ...
... Study 1, conducted by the National Cancer Institute (NCI), enrolled 184 patients; safety information is available for 149 patients. VORAXAZE was given at a dose of 50 Units/kg as an intravenous injection over 5 minutes. Patients with pre-VORAXAZE methotrexate concentrations >100 μmol/L were to recei ...
Effects of Smoked Cannabis ∆ and Oral -Tetrahydrocannabinol
... Richard E. Musty, PhD, and Rita Rossi are affiliated with the Department of Psychology, University of Vermont, Burlington, VT 05405. Richard E. Musty was supported by an individual project fellowship from the ...
... Richard E. Musty, PhD, and Rita Rossi are affiliated with the Department of Psychology, University of Vermont, Burlington, VT 05405. Richard E. Musty was supported by an individual project fellowship from the ...
ppt - Canadian Rheumatology Association
... Recommendations reviewed here are intended to be read in conjunction with Part I of CRA Recommendations for RA. These recommendations address specific safety questions that were identified a priori. They are not intended to cover all safety aspects concerning treatment with traditional and biologic ...
... Recommendations reviewed here are intended to be read in conjunction with Part I of CRA Recommendations for RA. These recommendations address specific safety questions that were identified a priori. They are not intended to cover all safety aspects concerning treatment with traditional and biologic ...
Clozaril® (clozapine)
... does not seem to cause tardive dyskinesia (TD), a potentially permanent side effect of standard antipsychotic medications. TD is characterized by involuntary movements such as grimacing, sucking/smacking of lips, and spasmodic movements of the extremities. It usually begins after several months of t ...
... does not seem to cause tardive dyskinesia (TD), a potentially permanent side effect of standard antipsychotic medications. TD is characterized by involuntary movements such as grimacing, sucking/smacking of lips, and spasmodic movements of the extremities. It usually begins after several months of t ...
Safety and efficacy of ustekinumab or golimumab in patients with chronic sarcoidosis
... Sarcoidosis is a systemic, granulomatous disease with highly variable clinical manifestations, natural history, and prognosis that primarily affects the lungs and lymphatic systems [1]. Sarcoidosis is diagnosed by clinical findings and corroborating histological evidence of non-caseating epithelioid ...
... Sarcoidosis is a systemic, granulomatous disease with highly variable clinical manifestations, natural history, and prognosis that primarily affects the lungs and lymphatic systems [1]. Sarcoidosis is diagnosed by clinical findings and corroborating histological evidence of non-caseating epithelioid ...
Allergic Rhinitis in Children
... itching and sneezing, while steroids are used to control the inflammation in the nasal lining and can help relieve eye symptoms. In general, allergists do not recommend using decongestant nasal sprays as these can actually worsen symptoms if used for more than a few days at a time. Steroids may be g ...
... itching and sneezing, while steroids are used to control the inflammation in the nasal lining and can help relieve eye symptoms. In general, allergists do not recommend using decongestant nasal sprays as these can actually worsen symptoms if used for more than a few days at a time. Steroids may be g ...
clinical investigations
... of predicted values. Patients were not using inhaled corticosteroids. Interventions: Twice-daily salmeterol aerosol, 42 mg, or placebo via metered-dose inhaler for 24 weeks. Backup albuterol was available. Measurements and results: Pulmonary function tests were performed before, during, and after tr ...
... of predicted values. Patients were not using inhaled corticosteroids. Interventions: Twice-daily salmeterol aerosol, 42 mg, or placebo via metered-dose inhaler for 24 weeks. Backup albuterol was available. Measurements and results: Pulmonary function tests were performed before, during, and after tr ...
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights
... possible, THALOMID® (thalidomide) is approved for marketing only through a special restricted distribution program: THALOMID REMS® program, approved by the Food and Drug Administration. ...
... possible, THALOMID® (thalidomide) is approved for marketing only through a special restricted distribution program: THALOMID REMS® program, approved by the Food and Drug Administration. ...
Treatment-resistant obsessive-compulsive disorder (OCD): current
... and randomized controlled studies written in English on treatment-resistant OCD. We also considered open-label studies and case series and/or reports, written in English. We reviewed the available evidence for different strategies and tried to delineate an evidence-based treatment algorithm for clin ...
... and randomized controlled studies written in English on treatment-resistant OCD. We also considered open-label studies and case series and/or reports, written in English. We reviewed the available evidence for different strategies and tried to delineate an evidence-based treatment algorithm for clin ...
Long-term Motor and Cognitive Outcome of Acute
... impaired attention and learning were found even in children who were considered fully recovered at the time of discharge. Risk factors for long-term severe neurologic sequelae were focal signs in the neurologic examination and abnormal neuroimaging on admission, confirmed infectious cause, and long h ...
... impaired attention and learning were found even in children who were considered fully recovered at the time of discharge. Risk factors for long-term severe neurologic sequelae were focal signs in the neurologic examination and abnormal neuroimaging on admission, confirmed infectious cause, and long h ...
Treatment of Tinnitus With a Customized, Dynamic Acoustic Neural
... the patients were instructed to listen to their acoustic stimulus for at least 2 hours per day, particularly at those times when their tinnitus was usually disturbing. They were instructed in how to achieve a high level of interaction with their tinnitus perception for the first 2-month period using ...
... the patients were instructed to listen to their acoustic stimulus for at least 2 hours per day, particularly at those times when their tinnitus was usually disturbing. They were instructed in how to achieve a high level of interaction with their tinnitus perception for the first 2-month period using ...
ABDA Winter, 2008 Newsletter - American Behcet`s Disease
... many have mixed emotions that symptoms can vary wildly about the exciting news of Sanya becoming from one sufferer to another and that remisan honorary Board member and a spokespersion is not the same in all. son for the ABDA. While at first I did not understand how one could feel this way, I As I’m ...
... many have mixed emotions that symptoms can vary wildly about the exciting news of Sanya becoming from one sufferer to another and that remisan honorary Board member and a spokespersion is not the same in all. son for the ABDA. While at first I did not understand how one could feel this way, I As I’m ...
Asthma: Approaches to Treatment and New Therapies
... likely than African American or Caucasian patients to be hospitalized for asthma. Before puberty, incidence is more common in male patients than female patients, and reverses to greater likelihood in female patients postpuberty. Incidence of asthma has grown over the last decade by 15 percent, makin ...
... likely than African American or Caucasian patients to be hospitalized for asthma. Before puberty, incidence is more common in male patients than female patients, and reverses to greater likelihood in female patients postpuberty. Incidence of asthma has grown over the last decade by 15 percent, makin ...
HYDROTHERAPY . Review on the effectiveness of its application
... to the number of outcomes being measured and compared (no designated primary outcome measurement), this study would be assessed as being well done and would rate an evidence level of 2. A single blind randomized controlled trial on the effectiveness of structured hydrotherapy program in the manageme ...
... to the number of outcomes being measured and compared (no designated primary outcome measurement), this study would be assessed as being well done and would rate an evidence level of 2. A single blind randomized controlled trial on the effectiveness of structured hydrotherapy program in the manageme ...
Ipilimumab
... end points (progressionfree survival) of a randomized, double-blind, ulticenter, phase 3 trial that was conducted to evaluate the safety and efficacy of nivolumab alone or nivolumab combined with ipilimumab in comparison with ipilimumab alone in patients with previously untreated metastatic melanoma ...
... end points (progressionfree survival) of a randomized, double-blind, ulticenter, phase 3 trial that was conducted to evaluate the safety and efficacy of nivolumab alone or nivolumab combined with ipilimumab in comparison with ipilimumab alone in patients with previously untreated metastatic melanoma ...
allergic rhinitis
... Benefit appears after 3 to 8 hours but maximum effect may require up to 2 weeks. Intranasal corticosteroids should be used regularly, but still have benefit if used on intermittent basis, for example in pollen season. Intranasal corticosteroids have been shown to improve quality ...
... Benefit appears after 3 to 8 hours but maximum effect may require up to 2 weeks. Intranasal corticosteroids should be used regularly, but still have benefit if used on intermittent basis, for example in pollen season. Intranasal corticosteroids have been shown to improve quality ...
Acute Osteomyelitis in Children
... cephalosporin, such as cefotaxime or ceftriaxone, or a fluoroquinolone.10,33,34 If these agents are not affordable, an older agent, chloramphenicol — which is currently not easy to obtain in developed countries — is a possibility, depending on the antibiogram profile. Its potential bone marrow effec ...
... cephalosporin, such as cefotaxime or ceftriaxone, or a fluoroquinolone.10,33,34 If these agents are not affordable, an older agent, chloramphenicol — which is currently not easy to obtain in developed countries — is a possibility, depending on the antibiogram profile. Its potential bone marrow effec ...
2015 Explorer - UCLA School of Dentistry
... risk for implant fractures associated with narrowdiameter implants could be minimized. While initial studies have shown that TiZr implants have excellent survival with minimal bone loss, further studies are still needed. The UCLA School of Dentistry is currently participating as one of the four cent ...
... risk for implant fractures associated with narrowdiameter implants could be minimized. While initial studies have shown that TiZr implants have excellent survival with minimal bone loss, further studies are still needed. The UCLA School of Dentistry is currently participating as one of the four cent ...
Product Monograph - Ask Novartis Pharma
... policy for one or all of its indicated uses. What is a Notice of Compliance with Conditions (NOC/c)? An NOC/c is a form of market authorization granted to a product on the basis of promising evidence of clinical effectiveness following review of the submission by Health Canada. Products authorized u ...
... policy for one or all of its indicated uses. What is a Notice of Compliance with Conditions (NOC/c)? An NOC/c is a form of market authorization granted to a product on the basis of promising evidence of clinical effectiveness following review of the submission by Health Canada. Products authorized u ...
Medicare National Coverage Determinations Manual Coverage Determinations
... programs may utilize services and devices which are excluded from coverage, e.g., acupuncture dorsal column stimulator, and family counseling services. In determining whether the scope of a pain program does necessitate inpatient hospital care, evaluate only those services and devices which are cove ...
... programs may utilize services and devices which are excluded from coverage, e.g., acupuncture dorsal column stimulator, and family counseling services. In determining whether the scope of a pain program does necessitate inpatient hospital care, evaluate only those services and devices which are cove ...
Pituitary adenoma, therapeutic approach and surgical results
... our series from which 13 were non functional macro adenomas and 2 were GH secreting adenomas. In the literature there are several theories concerning the precipitating factors in apoplexy, Biousse et al. divide this factors in: 1) factors associated with reduced blood flow, 2) acute increase in bloo ...
... our series from which 13 were non functional macro adenomas and 2 were GH secreting adenomas. In the literature there are several theories concerning the precipitating factors in apoplexy, Biousse et al. divide this factors in: 1) factors associated with reduced blood flow, 2) acute increase in bloo ...
Management of multiple sclerosis
Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.