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and chronic rhinosinusitis (CRS)
and chronic rhinosinusitis (CRS)

... placebo in patients with CRSsNP. The lack of quality data regarding this treatment option is surprising given the frequency with which it is utilized. Three RCTs have compared two different antibiotics in patients with CRS, but none of these studies demonstrated one antibiotic to be superior to anot ...
Secondary Hemophagocytic Lymphohistiocytosis in Adults: An
Secondary Hemophagocytic Lymphohistiocytosis in Adults: An

... unregulated inflammation. Corticosteroids may be used as monotherapy for secondary causes of HLH; however, the physician should expect to broaden treatment if the disorder does not respond or progresses. In highly suspicious cases, treatment may be initiated before obtaining final results of all dia ...
Intradialytic Massage for Leg Cramps Among Hemodialysis Patients
Intradialytic Massage for Leg Cramps Among Hemodialysis Patients

... or at home following dialysis.(2) Cramps that occur during hemodialysis can lead to shortening of treatment or to reduction of fluid removal which may result in inadequate clearance of waste products, fluid overload, and hypertension.(2,3,4) Shortening of as little as one dialysis treatment per week ...
PHARMACY .s __.x... -.
PHARMACY .s __.x... -.

... protecting the patients they serve. The Section currently consists of over 107 individuals who are primarily engaged in compounding practice for a majority of their time. On their behalf we are writing regarding the request for nominations as published in the April 7 issue of the Federal Register, p ...
LEVAQUIN® (levofloxacin) Prescribing Information
LEVAQUIN® (levofloxacin) Prescribing Information

... Because fluoroquinolones, including LEVAQUIN, have been associated with serious adverse reactions [see Warnings and Precautions (5.1-5.14)] and for some patients uncomplicated urinary tract infection is self-limiting, reserve LEVAQUIN for treatment of uncomplicated urinary tract infections in patien ...
Early Diagnosis is Key to Enhancing Success of Type 1
Early Diagnosis is Key to Enhancing Success of Type 1

... potential side effects or safety profile). The way in which this vital information is obtained is by performing research in the form of a clinical trial. According to the Food and Drug Administration’s (FDA’s) website, “A clinical trial is a research study in human volunteers to answer specific heal ...
desmopressin acetate tablets
desmopressin acetate tablets

... have produced transient headache, nausea, flushing and mild abdominal cramps. These symptoms have disappeared with reduction in dosage. Central Diabetes Insipidus In long-term clinical studies in which patients with diabetes insipidus were followed for periods up to 44 months of desmopressin acetate ...
THE DIAGNOSIS AND TREATMENT OF PERIPHERAL LYMPHEDEMA
THE DIAGNOSIS AND TREATMENT OF PERIPHERAL LYMPHEDEMA

... is essential for appropriate therapy. In most patients, the diagnosis of lymphedema can be readily determined from the clinical history and physical examination. In other patients confounding conditions such as morbid obesity, venous insufficiency, occult trauma, and repeated infection may complicat ...
EVect of intensive exercise on patients with active rheumatoid arthritis
EVect of intensive exercise on patients with active rheumatoid arthritis

... However, the risks of bed rest and immobilisation are well known. Loss of muscle strength during immobilisation may add up to 1–2% a day,7–11 and is more pronounced in the presence of joint disease or injury.12–14 A decline of cardiorespiratory function even occurs in healthy subjects during volunta ...
Lovenox - Sanofi
Lovenox - Sanofi

... recommended dose of Lovenox is 30 mg every 12 hours administered by SC injection. Provided that hemostasis has been established, the initial dose should be given 12 to 24 hours after surgery. For hip replacement surgery, a dose of 40 mg once a day SC, given initially 12 (±3) hours prior to surgery, ...
PDF
PDF

... If abscess formation is noted in adults, urgent drainage is indicated. In children, the literature supports careful observation of medial and inferior abscesses in children younger than 9 years of age. Other types of infection in the orbit include fungal and parasitic causes. Invasive fungal disease ...
2015 American Thyroid Association Management Guidelines for
2015 American Thyroid Association Management Guidelines for

... The disorder lacks the characteristics of GD , and is caused by the high serum hCG of early pregnancy .  It is not associated with adverse pregnancy outcomes.  More severe degrees of gestational hyperthyroidism are associated with hyperemesis; affected women may develop biochemically overt hypert ...
What we mean when we talk about adherence in respiratory medicine
What we mean when we talk about adherence in respiratory medicine

... Respiratory clinicians have access to a wide range of efficacious therapies. Randomized controlled trials (RCTs) have repeatedly demonstrated the efficacy of licensed asthma and chronic obstructive pulmonary disease (COPD) therapies in terms of their ability to minimize symptom burden, improve health- ...
06.13 VV GB Mucocele by WY - Aspen Meadow Vets
06.13 VV GB Mucocele by WY - Aspen Meadow Vets

... peritonitis. The time course to leakage or rupture is unpredictable. Gallbladder mucoceles are the most common cause of gallbladder perforation. Most agree that morbidity and mortality rates for patients undergoing emergency cholecystectomy due to gall bladder rupture are higher than for patients un ...
Treatment of acute otitis externa with ciprofloxacin otic 0.2
Treatment of acute otitis externa with ciprofloxacin otic 0.2

... drug, we also included two more studies that used a 0.3% ciprofloxacin product (Table 2).14,16 The ciprofloxacin dose of the ear solutions used in the individual studies was comparable. The majority planned a 7-day application phase, during which the study participants applied three drops to each ea ...
Supplement to Seminars in Cutaneous Medicine and Surgery
Supplement to Seminars in Cutaneous Medicine and Surgery

... he breadth and diversity of dermatology, the speed at which our understanding of skin pathophysiology has improved, and the introduction of new therapies combine to make this field interesting and challenging. The expanding scope of our specialty also creates a broad range of educational needs for p ...
Management of Infusion-related Reactions following Daratumumab
Management of Infusion-related Reactions following Daratumumab

... ✦ Received ≥3 prior lines of therapy, including a Pi and an imiD, in any order during the course of treatment, or disease was double refractory to a Pi and an imiD ✦ eastern cooperative oncology group performance status of 0 to 2 ✦ excluded patients who received prior allogeneic stem cell transplant ...
A 38-Year-Old Woman with Urinary Frequency
A 38-Year-Old Woman with Urinary Frequency

... voiding cystourethrogram. The renal collecting system and ureters were normal on intravenous pyelography, ruling out stones as the cause of her symptoms. Although not applicable in this case, it should be noted that the finding of hematuria in a patient with irritative voiding symptoms mandates an e ...
Guidance from the literature
Guidance from the literature

... system. Grade 1 is normal function. Grade 2 is slight weakness but no synkinesis (involuntary movement accompanying a voluntary movement). Grade 3 is obvious weakness and some mass movement. Grade 4 is inability to elevate the brow, significant synkinesis, and obvious weakness. Grade 5 is barely per ...
Vertigo
Vertigo

... • 71 year old man presented with several months of episodic spinning, lightheadedness and imbalance – Last episode occurred for 10 seconds when her got our of been. He sat down and felt normal within in 20 seconds – He has been awakened by a spinning sensation – A more recent spell was described at ...
LEVAQUIN Prescribing Information
LEVAQUIN Prescribing Information

... Because fluoroquinolones, including LEVAQUIN, have been associated with serious adverse reactions [see Warnings and Precautions (5.1-5.14)] and for some patients ABS is self-limiting, reserve LEVAQUIN for treatment of ABS in patients who have no alternative treatment options. 1.15 Usage To reduce th ...
Neurological Factors in Violent Behavior (The Dyscontrol Syndrome)
Neurological Factors in Violent Behavior (The Dyscontrol Syndrome)

... and the role of personality disorders and mental illness is so obvious, that the part played by brain damage and metabolic disorders is often overlooked. This is unfortunate because the most dangerous symptom of organic disease-unpredictable attacks of uncontrollable rage in response to seemingly tr ...
IFP addendum_US.book
IFP addendum_US.book

... monitoring is especially important for patients whose growth is not complete at implant. Consideration should be given to replacement of the extension with one of greater length during other elective surgery procedures, such as during the regular changeout of neurostimulators that must occur because ...
DVM Notes 2015 SVS CE Symposium - Seattle Veterinary Specialists
DVM Notes 2015 SVS CE Symposium - Seattle Veterinary Specialists

... Dr. Carr received her veterinary medical degree from Washington State University. After graduation, Dr. Carr joined a small animal referral and emergency hospital for a year-long internship and then went on to complete a residency in Diagnostic Imaging at the University of California-Davis Veterinar ...
glaucoma - Australian Doctor
glaucoma - Australian Doctor

... potential responses from each of 58 segments of the visual field out to 24°, compared with conventional VEP which records only a mass signal dominated by the central field. The visual stimulus is a checkerboard pattern of pseudo-randomly reversing checks at each of the 58 sites. The patient is requi ...
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Management of multiple sclerosis



Several therapies for multiple sclerosis (MS) exist, although there is no known cure. Multiple sclerosis is a chronic inflammatory demyelinating disease that affects the central nervous system (CNS).The most common initial course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable attacks (relapses) followed by periods of relative remission with no new signs of disease activity. After some years, many of the people who have this subtype begin to experience neurologic decline without acute relapses. When this happens it is called secondary progressive multiple sclerosis. Other, less common, courses of the disease are the primary progressive (decline from the beginning without attacks) and the progressive-relapsing (steady neurologic decline and superimposed attacks). Different therapies are used for patients experiencing acute attacks, for patients who have the relapsing-remitting subtype, for patients who have the progressive subtypes, for patients without a diagnosis of MS who have a demyelinating event, and for managing the various consequences of MS.The primary aims of therapy are returning function after an attack, preventing new attacks, and preventing disability. As with any medical treatment, medications used in the management of MS may have several adverse effects, and many possible therapies are still under investigation. At the same time different alternative treatments are pursued by many patients, despite the paucity of supporting, comparable, replicated scientific study.This article focuses on therapies for standard MS; borderline forms of MS have particular treatments that are excluded.
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