A Distinct and Parallel Pathway for the Nuclear Import of an mRNA
... and one member, human Crm1, was identified via its interaction with a repeat-containing nucleoporin (Fornerod et al., 1997a; Görlich et al., 1997; Wolff et al., 1997). Homology to known members of the b karyopherin family suggested that these proteins may function as karyopherins, raising the possib ...
... and one member, human Crm1, was identified via its interaction with a repeat-containing nucleoporin (Fornerod et al., 1997a; Görlich et al., 1997; Wolff et al., 1997). Homology to known members of the b karyopherin family suggested that these proteins may function as karyopherins, raising the possib ...
F1-Single Domain Antibody Service.ai
... An immunized sdAb phage display library was constructed from PBMCs after animal immunization. A panel of sdAbs with good expression, high stability and affinity were isolated using GenScript’s patented technology-FASEBA platform. Three independent sdAbs were identified based on high-affinity binding ...
... An immunized sdAb phage display library was constructed from PBMCs after animal immunization. A panel of sdAbs with good expression, high stability and affinity were isolated using GenScript’s patented technology-FASEBA platform. Three independent sdAbs were identified based on high-affinity binding ...
Dynamics of Protein Metabolism in the Ruminant
... glycoproteins of mucus). Energy substrates come from the residual fermentable fibre, the glycocalyx of rumen microorganisms, starch and other polysaccharides that have resisted rumen and enteric digestion. As the amount of fermentable energy from the diet reaching the lower tract increases, microbia ...
... glycoproteins of mucus). Energy substrates come from the residual fermentable fibre, the glycocalyx of rumen microorganisms, starch and other polysaccharides that have resisted rumen and enteric digestion. As the amount of fermentable energy from the diet reaching the lower tract increases, microbia ...
Bioinformatics analysis of experimentally determined protein
... located in the nucleus and cytoplasm (Fig. 2d). This is consistent with the known bias of massspectrometry approaches towards nuclear proteins (Von Mering 2002). Interestingly, in the nucleus the essential complexes outnumber the non-essential complexes, a bias that is inverted in the cytoplasm-asso ...
... located in the nucleus and cytoplasm (Fig. 2d). This is consistent with the known bias of massspectrometry approaches towards nuclear proteins (Von Mering 2002). Interestingly, in the nucleus the essential complexes outnumber the non-essential complexes, a bias that is inverted in the cytoplasm-asso ...
Prolyl Isomerases –Old Proteins as New Therapeutic Targets
... pharmacological profile. The main (but by no means prohibitive) difficulty is due to the somewhat higher structural complexity of the natural PPIase inhibitors as compared to “classical” synthetic molecules typically made by medicinal chemists. Unfortunately, there exists nowadays a certain reluctan ...
... pharmacological profile. The main (but by no means prohibitive) difficulty is due to the somewhat higher structural complexity of the natural PPIase inhibitors as compared to “classical” synthetic molecules typically made by medicinal chemists. Unfortunately, there exists nowadays a certain reluctan ...
... A new sample of the peptide was cleaved with cyanogen bromide, and the first five residues of each peptide were: Ala-Arg-Asp-Phe-Ser Lys-Val-Leu-Ser A new sample of the same peptide was cleaved with trypsin, and the first five residues of each peptide were: Ala-Arg-Asp-Phe-Ser Val-Leu-Ser What is th ...
Evolvement of LEM proteins as chromatin tethers at the nuclear
... RRM motif. Noteworthy, database searches showed, that ...
... RRM motif. Noteworthy, database searches showed, that ...
Creating Multiple Sequence Alignments
... You can change the Style in which you want to see the 3D structure. The default display presented in the figure for single structures is a combination of Style/Rendering Shortcuts: Worms and Style/Coloring Shortcuts: Secondary Structure, which show a worm backbone, no side chains, and solid objects ...
... You can change the Style in which you want to see the 3D structure. The default display presented in the figure for single structures is a combination of Style/Rendering Shortcuts: Worms and Style/Coloring Shortcuts: Secondary Structure, which show a worm backbone, no side chains, and solid objects ...
ACT Science Practice Test 1 ANSWERS File
... d. Curve 2 is not related to drug resistance. b. The unshaded region in curve 1 corresponds to strains of bacteria that are resistant to antibiotics. Thus, curve 2 arises from the survival of these strains. 9. Which of the following conclusions is NOT consistent with the results of the experiment? a ...
... d. Curve 2 is not related to drug resistance. b. The unshaded region in curve 1 corresponds to strains of bacteria that are resistant to antibiotics. Thus, curve 2 arises from the survival of these strains. 9. Which of the following conclusions is NOT consistent with the results of the experiment? a ...
Slide 1
... Specific enzymes carry out these modifications by recognizing specific target sequences near the modification site. ...
... Specific enzymes carry out these modifications by recognizing specific target sequences near the modification site. ...
Teaching old NCATs new tricks: using non
... Identifying the relatively small number of proteins translated in response to a specific pharmacological stimulation can be extremely difficult using established stable isotope labeling techniques, as there is no means to enrich for the labeled subproteome. In addition, proteins of low abundance, th ...
... Identifying the relatively small number of proteins translated in response to a specific pharmacological stimulation can be extremely difficult using established stable isotope labeling techniques, as there is no means to enrich for the labeled subproteome. In addition, proteins of low abundance, th ...
Renal tubular transp..
... Na+ absorbed by active transport mechanisms, NOT by TM mechanism. Basolateral ATPases establish a gradient across the tubule wall. Proximal tubule is very permeable to Na+, so ions flow down gradient, across membranes. Microvilli create large surface area for absorption. Electrical gradient c ...
... Na+ absorbed by active transport mechanisms, NOT by TM mechanism. Basolateral ATPases establish a gradient across the tubule wall. Proximal tubule is very permeable to Na+, so ions flow down gradient, across membranes. Microvilli create large surface area for absorption. Electrical gradient c ...
Drug delivery systems based on sugar
... on hepatocyte surfaces (50,000 to 500,000 per cell) [9]. In addition to lectin receptors that are regularly involved in endocytosis, those that are not may also be targeted. For example, lectin-like 'homing' receptors on lymphocytes recognize so-called cell adhesion molecules (CAM) that contain carb ...
... on hepatocyte surfaces (50,000 to 500,000 per cell) [9]. In addition to lectin receptors that are regularly involved in endocytosis, those that are not may also be targeted. For example, lectin-like 'homing' receptors on lymphocytes recognize so-called cell adhesion molecules (CAM) that contain carb ...
Experiment - 11 Binary fission (Amoeba) Budding (Yeast)
... Shubhankar was given two permanent slides, one of binary fission in amoeba and the other of budding in yeast. He was asked to determine any one difference in the nucleus of the two. One such difference is (a) presence of single nucleus each in amoeba, yeast cell and its attatched bud. (b) presence o ...
... Shubhankar was given two permanent slides, one of binary fission in amoeba and the other of budding in yeast. He was asked to determine any one difference in the nucleus of the two. One such difference is (a) presence of single nucleus each in amoeba, yeast cell and its attatched bud. (b) presence o ...
Identification of a novel human ... through its interaction with the ...
... CHX (pAS2-1 contains the CYH2 gene which restores CHX sensitivity to CG1945 cells). This enabled confirmation of the bait dependency of LacZ activation and subsequent isolation of the pACT2 plasmids encoding interacting proteins by standard methodology (23). Back transformations were then performed ...
... CHX (pAS2-1 contains the CYH2 gene which restores CHX sensitivity to CG1945 cells). This enabled confirmation of the bait dependency of LacZ activation and subsequent isolation of the pACT2 plasmids encoding interacting proteins by standard methodology (23). Back transformations were then performed ...
Alight-inducible organelle targeting system for dynamically
... Pharmacological tools are significantly faster, but many are not quickly reversible due to high binding affinities and the reliance on drug washout (Haruki et al., 2008). In addition, pharmacological approaches lack generality; not all proteins can be easily designed for drug targeting. Compared to ...
... Pharmacological tools are significantly faster, but many are not quickly reversible due to high binding affinities and the reliance on drug washout (Haruki et al., 2008). In addition, pharmacological approaches lack generality; not all proteins can be easily designed for drug targeting. Compared to ...
Divergent or just different Rozeboom, Henriette
... of eukaryotic cells. In 1965 hen egg-white lysozyme (HEWL, C (chicken) type) was the very first enzyme of which the atomic structure was solved (Blake et al., 1965). Later, structures were determined of goose type (G type) (Grütter et al., 1983), phage-type (T4) (Matthews et al., 1974) and invertebr ...
... of eukaryotic cells. In 1965 hen egg-white lysozyme (HEWL, C (chicken) type) was the very first enzyme of which the atomic structure was solved (Blake et al., 1965). Later, structures were determined of goose type (G type) (Grütter et al., 1983), phage-type (T4) (Matthews et al., 1974) and invertebr ...
The A. thaliana Disease Resistance Gene RPS2
... within the 35 kb region were isolated and named cDNA-1 to cDNA-6 (Figure 1 D). With the exception of cDNA-2, which hybridized to two distinct transcripts, each cDNA clone hybridized to one of the seven transcripts identified previously, thereby matching each transcript with a cDNA clone. As shown in ...
... within the 35 kb region were isolated and named cDNA-1 to cDNA-6 (Figure 1 D). With the exception of cDNA-2, which hybridized to two distinct transcripts, each cDNA clone hybridized to one of the seven transcripts identified previously, thereby matching each transcript with a cDNA clone. As shown in ...
Proteins - MATERI KULIAH PANGAN
... concentrations of inorganic electrolytes and nonprotein organic compounds do not vary appreciably from sample to sample, and that differences in the refractive index reflect primarily differences in protein concentration. ...
... concentrations of inorganic electrolytes and nonprotein organic compounds do not vary appreciably from sample to sample, and that differences in the refractive index reflect primarily differences in protein concentration. ...
The Carboxyl-Terminal Region of Protein C Is
... (Fig 4e). Mock-transfected CHO cells did not show any specific immunolabelling (Fig 4g and h). From these results, we conclude that the transport of PC407 and PC408 from rough ER to the Golgi apparatus is blocked and that these mutant proteins are retained in the rough ER, whereas PC409 was transpor ...
... (Fig 4e). Mock-transfected CHO cells did not show any specific immunolabelling (Fig 4g and h). From these results, we conclude that the transport of PC407 and PC408 from rough ER to the Golgi apparatus is blocked and that these mutant proteins are retained in the rough ER, whereas PC409 was transpor ...