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73737373 - Restless Legs Syndrome Foundation
73737373 - Restless Legs Syndrome Foundation

Syrovaya Anna Olegovna, Kharkov National Medical University
Syrovaya Anna Olegovna, Kharkov National Medical University

... antipyretic activities1,2,3. It is well known that the combination of several components in a single medicinal product promotes its specific action spectrum4. It is also known that caffeine is able to enhance analgesic, anti-inflammatory and other effects of drugs5,6,7. Therefore, it was promising ...
Substance Abuse
Substance Abuse

... – alpha-2 adrenergic receptor agonist, reduces catecholamine release in the sympathetic nervous system and may decrease withdrawal symptoms in patients taking low doses of opioids – Up to 1.2 mg per day in divided doses used – 0.1 mg doses to 0.2 mg generally ...
Local Anesthetics
Local Anesthetics

... They contrast with analgesics (painkillers), which relieve pain without eliminating sensation. These drugs are generally administered to facilitate surgery. A wide variety of drugs are used in modern anesthetic practice. Many are rarely used outside of anesthesia, although others are used commonly b ...
The Challenges of Methamphetamine
The Challenges of Methamphetamine

... – alpha-2 adrenergic receptor agonist, reduces catecholamine release in the sympathetic nervous system and may decrease withdrawal symptoms in patients taking low doses of opioids – Up to 1.2 mg per day in divided doses used – 0.1 mg doses to 0.2 mg generally ...
Coma after levetiracetam overdose
Coma after levetiracetam overdose

... and mild adverse effect profile, levetiracetam overdose can be complicated by life-threatening symptoms. A recent case report and literature review on this subject reported three adult cases of an overdose with one patient requiring intubation and mechanical ventilation.8 Exact doses corrected for w ...
Potential Neurotoxicity of Ketamine in the
Potential Neurotoxicity of Ketamine in the

... ketamine had returned to baseline levels. In situ hybridization also showed a remarkable increase in mRNA signals for the NMDA NR1 subunit in the frontal cortex. These data demonstrate that ketamine administration results in a dose-related and exposuretime dependent increase in neuronal cell death d ...
Toxicology Introduct..
Toxicology Introduct..

... male's larger blood volume and greater tissue mass which dilute the chemical. · For substances that are injected intramuscularly, lower blood levels can be expected with those drugs in individuals (usually men) with a greater muscle mass. · Also, drugs with a high lipid coefficient that normally par ...
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES, KARNATAKA
RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES, KARNATAKA

... medical and social problem. It is estimated that there are currently about 6.29 % of population is affected worldwide by neurological disorders. This figure is projected to 6.39 % in 2015 and 6.77 % in 2030. Presently available pharmacological treatment for neurodegenerative disorders are symptomati ...
Addiction (1999) 94(5), 665-674
Addiction (1999) 94(5), 665-674

... individuals metabolize thc drug may contribute to differences in withdrawal symptoms reported by patients on methadone substitution following acute daily dosage (Dyer & White, 1997). Tolerance to the various effects of most centrally acting drugs builds up over repeated use. However, tolerance may d ...
medication use in breastfeeding women
medication use in breastfeeding women

... previous effective treatments.31 The antidepressant should be started at the lowest effective dose and increased slowly. The clinical condition of the mother and infant should be monitored, particularly for low birth weight and premature infants.31,32 Selective serotonin reuptake inhibitors: (SSRIs) ...
A Treatise on Collinsonia canadensis
A Treatise on Collinsonia canadensis

... remedy. It relieves the congestion and gives tone to the enfeebled organs. It is also an excellent remedy in the following diseases of the digestive system: chronic gastritis or indigestion, where the circulation is defective and digestion is attended with pain and nervous symptoms occurring before ...
Preview the material
Preview the material

... the nervous system’s normal functioning, so interfering with it If marijuana is consumed in foods or beverages, these can have profound effects. effects are somewhat delayed— usually appearing after 30 For example, THC is able to alter the functioning minutes to 1 hour— because the drug must first p ...
PSUEDOMONAS AERUGINOSA INFECTIONS IN NIGERIA  Original Article
PSUEDOMONAS AERUGINOSA INFECTIONS IN NIGERIA Original Article

... Objective: The objective of the study was to determine the most cost effective antibacterial agents in the treatment of Pseudomonas aeruginosa infections in Lagos metropolis. Methods: Cost effectiveness analysis of ciprofloxacin, ceftazidime and gentamicin among routinely used antibacterial agents a ...
Marijuana Myths and Facts
Marijuana Myths and Facts

Briuglia-etal-DDTR-2015-Influence-of-cholesterol-on
Briuglia-etal-DDTR-2015-Influence-of-cholesterol-on

Caffeine: Hero or Zero Caffeine is the most widely used, legal drug
Caffeine: Hero or Zero Caffeine is the most widely used, legal drug

... to  stay  hydrated  when  drinking  beverages  containing  caffeine  or  taking  caffeine   supplements.     ...
effect of trikatu, an ayurvedic prescription, on the pharmacokinetic
effect of trikatu, an ayurvedic prescription, on the pharmacokinetic

... brought about by piperine has not been explained so far (2, 3). We believe it could be. because of increased splanchnic blood flow and rate of transport of drugs across the gastrointestinal mucous brought about by Trikatu (9). The other important actions of Trikatu on the gastrointestinal tract incl ...
PENTAZOCINE VERSUS PENTAZOCINE WITH RECTAL DICLOFENAC FOR POSTOPERATIVE PAIN
PENTAZOCINE VERSUS PENTAZOCINE WITH RECTAL DICLOFENAC FOR POSTOPERATIVE PAIN

... analgesia. Intramuscular pentazocine, a partial agonist opioid is widely used in low resources countries for postoperative analgesia with limited effect3. A multimodal approach has been proposed to be more effective2. Non-steroidal anti-inflammatory drugs (NSAIDs) have beneficial effect on postopera ...
WCBR 2015 Panel Schedule - Winter Conference on Brain Research
WCBR 2015 Panel Schedule - Winter Conference on Brain Research

... Mouse Models of Genetic Susceptibility for Complex Psychiatric Disorders Neuronal endocytosis in brain development, plasticity and disease Genetic and environmental modulation of prefrontal cortex pathways in health and disease: from rodents to humans Amphetamine neurotoxicity: beyond dopamine/The S ...
Aminobutyric Acid (GABA) - Journal of Pharmacology and
Aminobutyric Acid (GABA) - Journal of Pharmacology and

... types of reward. GVG dose dependently decreased responding for cocaine on both schedules of reinforcement, suggesting that GVG attenuated the reward value of the cocaine. Responding for food was also decreased by GVG, suggesting that the effects of increased GABA levels induced by GVG may have a gen ...
Stress-induced enhancement of response inhibition
Stress-induced enhancement of response inhibition

... Summary Stress is a well-known modulator of cognitive functions. These effects are, at least in part, mediated by glucocorticoid stress hormones which act via two receptor types in the brain, glucocorticoid receptors (GR) and mineralocorticoid receptors (MR). Here, we examined whether stress affects ...
Do THE BENEFITS OUTWEIGH THE RISKS?
Do THE BENEFITS OUTWEIGH THE RISKS?

... the following: chain stores, mail services, independent non-federal facilities. clinics, food stores, long-term care, federal facilities, home health, HMO, and other categories. ld. 11 Id. In 2005, the biopharmaceutical industry spent a total of$51.3 billion in research and development. PHARMACEUTIC ...
Full Prescribing Information
Full Prescribing Information

... The most characteristic effect of papaverine is relaxation of the tonus of all smooth muscle, especially when it has been spasmodically contracted. Papaverine Hydrochloride apparently acts directly on the muscle itself. This relaxation is noted in the vascular system and bronchial musculature and in ...
STABILITY INDICATING HPTLC METHOD FOR SIMULTANEOUS DETERMINATION OF  TELMISARTAN AND RAMIPRIL IN TABLETS 
STABILITY INDICATING HPTLC METHOD FOR SIMULTANEOUS DETERMINATION OF  TELMISARTAN AND RAMIPRIL IN TABLETS 

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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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