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HerbClip™
HerbClip™

... compound's ability to restore libido in aging male rats, to restore fertility which has been reduced by alcohol or tobacco use, to reduce anxiety while withdrawing from alcohol and, in what may be an error of translation, to restore the libido of male rats which are "addicted to tetrahydrocannabinol ...
Half-Life
Half-Life

...  Half-Life: The time it takes a substance to decrease to half of a previous value.  Half-Life is a good predictor of how long a substance will exist.  Drug Half-Life: The time required for the total amount of a drug in blood to diminish by half, once the drug reaches its peak concentration. See P ...
The role of the quantity in the prosecution of drug offences
The role of the quantity in the prosecution of drug offences

... Hence the international significance of the role of the quantity of substance when it is instrumental in the distinction in national law between acts intended for personal use and those intended for sale. Law at European level Over the last 10 years, the European Union has considerably increased its ...
PPT here
PPT here

... Most chemotherapeutic agents are highly toxic with narrow therapeutic index. They also effect normal dividing cells. Undesirable side effects- nausea, vomiting, hair loss, diarrhea, etc. Development of multi drug resistance by the tumor cells. Hypoxic cells resistant to radiotherapy. Irregular ...
Lidocaine
Lidocaine

... following anesthesia. The liver damage appears to be a hypersensitivity type of hepatitis which is independent of dose. • Halothane can cause malignant hyperthermia (which need treatment with Dantrolene i.v.) uterine atony and postpartum hemorrhage. It has a teratogenic activity. ...
1 Lecado 100/25 mg Modified-release Tablets Lecado 200/50 mg
1 Lecado 100/25 mg Modified-release Tablets Lecado 200/50 mg

... Take special care with Lecado If you are currently being, or have ever been, treated with levodopa on its own. You must wait for at least 12 hours before you can start taking Lecado tablets; • if you suffer from movement disorders such as facial muscle twitches, muscle rigidity and stiffness, diffic ...
SPARC Investor Presentation - sun pharma advanced research
SPARC Investor Presentation - sun pharma advanced research

... • Phase II study in India ongoing • To be filed in US as 505(b)(2) in Q1 2011-12 An Antihypertensive drug with high dose, high solubility • Phase II study ongoing • To be filed in US as 505(b)(2) in Q2 2011-12 A Cardiovascular agent with high dose and high solubility • Pharmacokinetics studies are o ...
2.3 Drug control under the League of Nations, 1920-1945
2.3 Drug control under the League of Nations, 1920-1945

... One specific problem in the initial years of international drug control was the fact that several key players –in particular the United States – did not join the League of Nations. Thus, a number of rather complex institutional solutions had to be found (some of which are still in existence) to miti ...
purchase mandrax
purchase mandrax

... Valium), which is cheap and widely available from pharmacies and other retail outlets. While there may be many reasons for such misuse, conflict-related poverty, social displacement and mental health problems (including chronic anxiety, depression and post-traumatic stress disorder) are known to hav ...
Marketed Unapproved Drugs
Marketed Unapproved Drugs

... enforcement policy.8 FDA considers all of these products to be unapproved and marketed illegally, but generally uses its enforcement discretion to take action against firms marketing products the agency believes present a potential safety risk, lack evidence of effectiveness, or are deceptively prom ...
PharmacoTheraputics
PharmacoTheraputics

...  Expensive  Lack of clinical rationale for use Bioequivalence of Thyroxine Products: o Basics: FDA approved generics may differ from brands by up to 33% o Issue: narrow therapeutic index drug; slight dose alterations can lead to sub/supratherapeutic effects o Recommendations: ...
11127sgp06ppt
11127sgp06ppt

... administration of diazepam to nursing mothers has been reported to cause their infants to become lethargic and to lose weight. As a general rule, nursing should not be undertaken by mothers who must use Xanax. Geriatric Use • The elderly may be more sensitive to the effects of benzodiazepines. They ...
- White Rose Research Online
- White Rose Research Online

... help in meeting the needs of aging populations with multiple chronic diseases, the targeting of medicines to individuals (personalization) to significantly increase efficacy and reduce overall cost, and computerized clinical decision support that can reduce the burden of harm caused by adverse drug ...
A Randomized, Double-Blind, Placebo
A Randomized, Double-Blind, Placebo

... motor and phonic tics and a wide range of behavioral problems, including attention deficit with or without hyperactivity, obsessivecompulsive behavior, and impulse control problems (Jankovic, 2001). The pharmacological treatment of TS usually consists of antidopaminergic drugs and a wide array of ot ...
Tramadol - Wayne Anderson
Tramadol - Wayne Anderson

... be responsible for their own behavior and should not engage in any dangerous activity if there is any question of impairment. All medications have side effects and drug interactions, some serious, some fatal. Let all of your practitioners and pharmacist know about every substance used. Alcohol, herb ...
32. MaryAnn O   Hara et al. A review of 12 commonly used medicinal
32. MaryAnn O Hara et al. A review of 12 commonly used medicinal

... science-based evidence about product to consumers ...
Nimesulide (PDF, 210KB, File is accessible)
Nimesulide (PDF, 210KB, File is accessible)

... patients with a history of ulcer, particularly if complicated with haemorrhage or perforation (see Section 3), and in the elderly. These patients should commence treatment on the lowest dose available. Combination therapy with protective agents (e.g. misoprostol or proton pump inhibitors) should be ...
SPARC Investor Presentation
SPARC Investor Presentation

... • Phase II study in India ongoing • To be filed in US as 505(b)(2) in Q1 2011-12 An Antihypertensive drug with high dose, high solubility • Phase II study ongoing • To be filed in US as 505(b)(2) in Q2 2011-12 A Cardiovascular agent with high dose and high solubility • Pharmacokinetics studies are o ...
Glycine receptors in the central nervous system
Glycine receptors in the central nervous system

... likely to encounter this particular drug. As a drug ethanol is commonly consumed for its acute effects. In humans these effects are usually easy to distinguish; an initial pleasurable feeling, (including anxiolysis and elevated mood) and signs of psychomotor stimulation, e.g. increased talkativeness ...
Anti-viral agent
Anti-viral agent

... a. Good oral bioavailability when given with or without food b. Efficacy increases when combined with two nucleoside RT inhibitors c. Side effects: GI disturbances & rashes ...
Document
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Elavil (amitriptyline)
Elavil (amitriptyline)

... central nervous system. Elavil also has other pharmacological effects, which are associated with its side effects. Depression and other mental disorders may be due to abnormally low levels of certain neurotransmitters in the brain. This abnormality may in turn produce changes in affected areas of th ...
Alzheimer`s Disease and Other Dementias
Alzheimer`s Disease and Other Dementias

... • Dementia (n): a chronic or persistent disorder of the mental processes caused by brain disease or injury and marked by memory disorders, personality changes, and impaired reasoning. • Delirium (n): an acutely disturbed state of mind that occurs in fever, intoxication, and other disorders and is ch ...
Drug Safety Initiative - Psychiatric Medication Awareness Group
Drug Safety Initiative - Psychiatric Medication Awareness Group

... Pharmacokinetics is a discipline that uses mathematical models to describe and predict the time-course of drug concentrations in body fluids.1 The pharmacokinetic issues are vast in treating the geriatric patient and must be considered with each drug ordered, condition changes, sex or race of the ge ...
DOSE DEPENDENT EFFICACY OF LACOSAMIDE IN PROTECTION OF PENTYLENETETRAZOL  Research Article
DOSE DEPENDENT EFFICACY OF LACOSAMIDE IN PROTECTION OF PENTYLENETETRAZOL Research Article

... patients are still not seizure free [1, 2]. Anything that disturbs the normal pattern of neuronal activity such as illness, brain damage, abnormal brain development can lead to seizure. It can be described as the repetitive occurrence of abnormal bioelectrical synchronization of a large number of ne ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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