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מבחן גמר בנוירולוגיה - 2008
מבחן גמר בנוירולוגיה - 2008

... a. Verapamil is useful in the prevention of pain related to stable angina pectoris b. Nifedipine is useful in the prevention of pain related to stable angina pectoris c. Diltiazem only affects the blood vessels and does not affect the heart d. Verapamil causes Tachycardia due to its direct effect on ...
Vomiting
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... intravenous administration or if given at high doses. Metoclopramide controls peripherally induced and humorally mediated vomiting due to numerous conditions, but it should be avoided if gastrointestinal obstruction is suspected because its prokinetic properties could predispose these patients to ga ...
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Study of the interaction between 3,4- methylenedioximethamphetamine and the endocannabinoid system
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... NAc through an action of kappa opioid receptors located on presynaptic DA nerve terminals in these regions. Moreover, several studies have implicated CRF system in the mediation of many of the anxiogenic and aversive aspects of drug withdrawal (Sarnyai et al., 2001). Corticotropin-releasing factor ( ...
Hallucinogens - Multidisciplinary Association for Psychedelic Studies
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... and evoke feelings of spiritual significance. Thus, the term entheogen, derived from the Greek word entheos, which means ‘‘god within,’’ was introduced by Ruck et al. (1979) and has seen increasing use. This term suggests that these substances reveal or allow a connection to the ‘‘divine within.’’ A ...
Opioids - David Kan, MD
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Acute Pain Management in the Opioid Dependent Patient
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EFFECTS OF SYMPATHOMIMETICS ON CARDIOVASCULAR
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“Reefer Madness: Dude can you prescribe pot for my glaucoma
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Enhancement of Excessive Lever-Pressing After Post
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A Comparative Study Between Palonosetron and Granisetron to
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... wiping out Indian use of the plant. During the American Civil War, peyote use began spreading north from Mexico on a large ...
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The Mechanistic Classification of Addictive Drugs

... by Kir3/ G protein–coupled inwardly rectifying K+ (GIRK) channels coupled to MORs on the soma and the dendrites, in analogy to other parts of the brain [9], while MORs expressed on the pre-synaptic terminals decrease release by inhibiting Ca2+ channels or activating voltage-gated K+ channels [10]. M ...
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... panic disorders, obsessive compulsive disorder (OCD). These are link to many neurotransmitters. But gama-aminobutyric acid (GABA), norepi, 5HT are consider as having major influence on these disorders. R ...
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Cannabinoid receptor antagonist



The discovery of the endogenous cannabinoid system led to the development of CB1 receptor antagonists. The first cannabinoid receptor antagonist, rimonabant, was described in 1994. Rimonabant blocks the CB1 receptor selectively and it has been shown to decrease food intake and regulate body-weight gain. The prevalence of obesity worldwide is increasing dramatically and has a great impact on public health. The lack of efficient and well-tolerated drugs to cure obesity has led to an increased interest in research and development of cannabinoid antagonists. Cannabidiol, a naturally occurring cannabinoid, is a non-competitive CB1/2 antagonist.
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