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Slide 1
Slide 1

Combinatorial Platinum(IV)-Peptide/Co-drug Conjugates as Multimodal Targeted Anticancer Agents.
Combinatorial Platinum(IV)-Peptide/Co-drug Conjugates as Multimodal Targeted Anticancer Agents.

[4-20-14]
[4-20-14]

PowerPoint Presentation - Lecture 9
PowerPoint Presentation - Lecture 9

... Aldosterone promotes Na retention & K excretion. Block aldosterone & Na excreted, but H2O & K retained - Used to treat HTN primarily, - but not a 1st line drug. Also used in heart failure. - SE = hyperkalemia & 1st dose hypotension (more common with comb. Diuretic & ACE inhibitor. ...
Drugs acting on RAAS by Dr Vignesh S
Drugs acting on RAAS by Dr Vignesh S

181lec5
181lec5

2 receptor
2 receptor

What is mental life
What is mental life

... d. Potentiates muscle relaxation e. SE = EEG suppression (at high concentrations), trigger MH (rare), ↑ HR, ↓ BP, ↓ SVR (significant) i. BUT little effect on CO 6) Sevolurane = most commonly used agent a. Low solubility (rapid onset offset agent) and non pungent (ideal for inhalation) b. MAC = 1.7 c ...
Sample question
Sample question

Research and Development of Olopatadine hydrochloride, an
Research and Development of Olopatadine hydrochloride, an

1. ------IND- 2016 0145 HU- EN- ------ 20160405 --- --
1. ------IND- 2016 0145 HU- EN- ------ 20160405 --- --

No Slide Title
No Slide Title

Read more. - Griffin Discoveries
Read more. - Griffin Discoveries

CATECHOLAMINES - Drexel University College of Medicine
CATECHOLAMINES - Drexel University College of Medicine

Structural analysis of histamine receptors and its application in drug
Structural analysis of histamine receptors and its application in drug

... and the template proteins. Structure-based methods can be used effectively in several stages of drug design. For example, a structural protein model can be used to map the binding site, and explore novel sites for ligand design. These sites may provide opportunities increasing affinity and/or select ...
Document
Document

Krokodil - UCLA Brain Research Institute
Krokodil - UCLA Brain Research Institute

Materials and Methods
Materials and Methods

Reward and Drug Addiction
Reward and Drug Addiction

... detection. For measurement of detection threshold, the initial, noncontingent stimulus varied in intensity (at subreward levels), whereas the second, or response-contingent, stimulus was held constant at a rewarding intensity to maintain responding. Each point is the mean z score ± SEM, the differen ...
Alterations in Cardiovascular Function:
Alterations in Cardiovascular Function:

... Sympatholytic Drug Classes 1. Beta-adrenergic blockers aka “beta blockers” 2. Centrally acting alpha2 agonists 3. Alpha-adrenergic blockers ...
教案编写基本格式与要求
教案编写基本格式与要求

A1989U815100001
A1989U815100001

Document
Document

Baclofen: Interaction with GABA Receptor Leading to CNS Depression
Baclofen: Interaction with GABA Receptor Leading to CNS Depression

No Slide Title
No Slide Title

< 1 ... 70 71 72 73 74 75 76 77 78 ... 85 >

Discovery and development of angiotensin receptor blockers

The angiotensin receptor blockers (ARBs), also called angiotensin (AT1) receptor antagonists or sartans, are a group of antihypertensive drugs that act by blocking the effects of the hormone angiotensin II (Ang II) in the body, thereby lowering blood pressure. Their structure is similar to Ang II and they bind to Ang II receptors as inhibitors, e.g., [T24 from Rhys Healthcare].ARBs are widely used drugs in the clinical setting today, their main indications being mild to moderate hypertension, chronic heart failure, secondary stroke prevention and diabetic nephropathy.The discovery and development of ARBs is a demonstrative example of modern rational drug design and how design can be used to gain further knowledge of physiological systems, in this case, the characterization of the subtypes of Ang II receptors.
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