Presynaptic Release Probability Is Increased in Hippocampal
... NMDARs by relieving Mg2⫹ block (Wemmie et al. 2002). Depolarization-induced removal of Mg2⫹ block from the NMDAR is usually mediated by the activation of ␣-amino3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs). In specific situations, such as silent synapses that express few functiona ...
... NMDARs by relieving Mg2⫹ block (Wemmie et al. 2002). Depolarization-induced removal of Mg2⫹ block from the NMDAR is usually mediated by the activation of ␣-amino3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs). In specific situations, such as silent synapses that express few functiona ...
The Estrous Cycle
... The 21 -day interval between heats in cattle is dictated by the lifespan of a structure on the ovary called the corpus luteum (CL). Figure 1 illustrates the process of formation, development and regression of the CL. The CL originates from cells of an ovulatory follicle that is present on the day t ...
... The 21 -day interval between heats in cattle is dictated by the lifespan of a structure on the ovary called the corpus luteum (CL). Figure 1 illustrates the process of formation, development and regression of the CL. The CL originates from cells of an ovulatory follicle that is present on the day t ...
Serum Concentrations of Luteinizing Hormone, Growth Hormone
... phase based on day of the estrous cycle had serum progesterone (6.55 ng/mL) and estradiol concentrations (below assay sensitivity) consistent with a luteal-phase gilt. This gilt was not included in the statistical analyses. Serum progesterone concentrations in the remaining luteal-phase animals were ...
... phase based on day of the estrous cycle had serum progesterone (6.55 ng/mL) and estradiol concentrations (below assay sensitivity) consistent with a luteal-phase gilt. This gilt was not included in the statistical analyses. Serum progesterone concentrations in the remaining luteal-phase animals were ...
Kv4.2 mRNA Abundance and A-Type K Current Amplitude Are
... 1996; Shi et al., 1997). The molecular picture is further complicated by the ability of auxiliary channel subunits to transform non-inactivating, delayed rectifier K 1 channels into inactivating, A-type channels (Rettig et al., 1994; Heinemann et al., 1996). In spite of this complexity, only channel ...
... 1996; Shi et al., 1997). The molecular picture is further complicated by the ability of auxiliary channel subunits to transform non-inactivating, delayed rectifier K 1 channels into inactivating, A-type channels (Rettig et al., 1994; Heinemann et al., 1996). In spite of this complexity, only channel ...
Cell lysate and SR-enriched membrane fraction (SR - HAL
... 1). Moreover, events lasting more than 50 ms were more frequent in aldosterone-treated and hMR mice compared with WT. Distributions of log(FDHM) were fitted by 2 Gaussian distributions with 2 distinct peaks ~32 and 87 ms, but the frequency of long-lasting signals were larger in aldosteronetreated an ...
... 1). Moreover, events lasting more than 50 ms were more frequent in aldosterone-treated and hMR mice compared with WT. Distributions of log(FDHM) were fitted by 2 Gaussian distributions with 2 distinct peaks ~32 and 87 ms, but the frequency of long-lasting signals were larger in aldosteronetreated an ...
Andrew V. Schally - Nobel Lecture
... Figure 7. Molecular structure of thyrotropin-releasing hormone (TRH). We have conducted various physiological studies since 1962 with natural preparations of TRH (12, 13, 16) and confirmed and extended them by using synthetic TRH, demonstrating that the concentration of TSH in the plasma increased w ...
... Figure 7. Molecular structure of thyrotropin-releasing hormone (TRH). We have conducted various physiological studies since 1962 with natural preparations of TRH (12, 13, 16) and confirmed and extended them by using synthetic TRH, demonstrating that the concentration of TSH in the plasma increased w ...
The Hypothalamic pituitary axis part 1
... ACTH Site of Action: adrenal cortex Effects: mainly stimulates the synthesis of glucocorticoids (steroid hormones involved in glucose synthesis) in the zona fasciculata. ACTH also stimulates the synthesis of mineralocorticoids (steroid hormones involved in sodium retention) in the zona glomerulosa. ...
... ACTH Site of Action: adrenal cortex Effects: mainly stimulates the synthesis of glucocorticoids (steroid hormones involved in glucose synthesis) in the zona fasciculata. ACTH also stimulates the synthesis of mineralocorticoids (steroid hormones involved in sodium retention) in the zona glomerulosa. ...
Differential sensitivity of medium- and large
... application of N-methyl-D-aspartate (NMDA) and kainate. Inward currents and current densities induced by NMDA were signi®cantly smaller in large- than in medium-sized striatal neurons. The negative slope conductance for NMDA currents was greater in medium- than in large-sized neurons and more depola ...
... application of N-methyl-D-aspartate (NMDA) and kainate. Inward currents and current densities induced by NMDA were signi®cantly smaller in large- than in medium-sized striatal neurons. The negative slope conductance for NMDA currents was greater in medium- than in large-sized neurons and more depola ...
Regulation of inhibin/activin subunits and follistatin mRNA
... two independent assays. Results were quantified using a PhosphorImager (Molecular Dynamics/B&L Systems, Maarsen, The Netherlands) and data are expressed relative to GAPDH as relative units (ru). The RNase protection assays were conducted using two samples of total RNA from rat ovary and from rat tes ...
... two independent assays. Results were quantified using a PhosphorImager (Molecular Dynamics/B&L Systems, Maarsen, The Netherlands) and data are expressed relative to GAPDH as relative units (ru). The RNase protection assays were conducted using two samples of total RNA from rat ovary and from rat tes ...
Equine chorionic gonadotropin: an enigmatic but essential tool
... Costagliola, 2011), thereby allowing LH-like hormones to interact with cryptic sites and to signal through the FSH receptor. Thus, promiscuity of receptor binding, particularly in the FSH receptor, is the basis for dual activity of eCG, as its primary structure allows it to interact with this recept ...
... Costagliola, 2011), thereby allowing LH-like hormones to interact with cryptic sites and to signal through the FSH receptor. Thus, promiscuity of receptor binding, particularly in the FSH receptor, is the basis for dual activity of eCG, as its primary structure allows it to interact with this recept ...
Adrenal Insufficiency: A Guide for Families
... is prolonged administration of steroids to treat medical conditions, such as severe asthma or kidney, joint, or skin problems. This is also called iatrogenic adrenal insufficiency. When a child receives steroid therapy for more than one week, the steroids levels build up in the blood and shut down t ...
... is prolonged administration of steroids to treat medical conditions, such as severe asthma or kidney, joint, or skin problems. This is also called iatrogenic adrenal insufficiency. When a child receives steroid therapy for more than one week, the steroids levels build up in the blood and shut down t ...
Cutaneous Sensory Neurons Expressing the Mrgprd Receptor
... warmth to intense piercing or burning pain. The molecular mechanisms by which these sensations are mediated have only partially been uncovered, but recent evidence suggests that keratinocytes, the major cell type in the epidermis, can communicate with sensory neurons in response to certain stimuli ( ...
... warmth to intense piercing or burning pain. The molecular mechanisms by which these sensations are mediated have only partially been uncovered, but recent evidence suggests that keratinocytes, the major cell type in the epidermis, can communicate with sensory neurons in response to certain stimuli ( ...
Reproductive Biology of Salmoniform and Pleuronectiform Fishes with Special Reference to
... M. Amano / Aqua-BioSci. Monogr. 3: 39–72, 2010 ...
... M. Amano / Aqua-BioSci. Monogr. 3: 39–72, 2010 ...
Pituitary Disorders
... Cause may be genetic and congenital, autoimmune or idiopathic Multiple deficiency can be due to tumor – usually GH and gonadotropins are affected first ...
... Cause may be genetic and congenital, autoimmune or idiopathic Multiple deficiency can be due to tumor – usually GH and gonadotropins are affected first ...
Chapter 2 Steroid Biosynthesis and Regulation - Rose
... DHEA, and DHEAS. The steroid profiles produced in the zonæ fasciculata and reticularis are similar. It is not clear why there are two zonæ with the same products, although it has been suggested that the zona reticularis is more involved in adrenal androgen production. This is supported by the fact t ...
... DHEA, and DHEAS. The steroid profiles produced in the zonæ fasciculata and reticularis are similar. It is not clear why there are two zonæ with the same products, although it has been suggested that the zona reticularis is more involved in adrenal androgen production. This is supported by the fact t ...
Hormonal response of male green anole lizards
... because they represent a major postmaturation ontogenetic transition in body shape, perhaps owing to changes in hormone profiles at some critical body size at which males can compete for territories. Thus, an important question to ask is whether lightweight males that have low circulating levels of ...
... because they represent a major postmaturation ontogenetic transition in body shape, perhaps owing to changes in hormone profiles at some critical body size at which males can compete for territories. Thus, an important question to ask is whether lightweight males that have low circulating levels of ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... secondary infertile group, 2% had FSH serum levels below, 92% within and 6% above the normal range limits as shown in fig. 1. For LH, 2% have serum levels below, 90% within and 8% above normal range limits as shown in fig. 1. In the primary infertile group, 18% have FSH levels below, 46% within, and ...
... secondary infertile group, 2% had FSH serum levels below, 92% within and 6% above the normal range limits as shown in fig. 1. For LH, 2% have serum levels below, 90% within and 8% above normal range limits as shown in fig. 1. In the primary infertile group, 18% have FSH levels below, 46% within, and ...
Hypothalamus and Anterior Pituitary
... receptor, secretion, action, Kallman syndrome, clinical use. • TRH: structure, receptor, secreting cells, regulation, actions, clinical use. • GHRH: structure, receptor, secretion, patophysiology, clinical use. • SRIF: structure, receptor, secretion, analogs. • CRH: structure, receptors, regulat ...
... receptor, secretion, action, Kallman syndrome, clinical use. • TRH: structure, receptor, secreting cells, regulation, actions, clinical use. • GHRH: structure, receptor, secretion, patophysiology, clinical use. • SRIF: structure, receptor, secretion, analogs. • CRH: structure, receptors, regulat ...
HPG-axis hormones during puberty: A study on the association with
... gray matter density was observed in prefrontal and occipital areas, whereas decreased gray matter density was found in prefrontal, temporal and parietal areas (Peper et al., 2009a). Other HPG-axis hormones (testosterone, LH (Peper et al., 2009a) or FSH (unpublished data)) did not relate to cortical ...
... gray matter density was observed in prefrontal and occipital areas, whereas decreased gray matter density was found in prefrontal, temporal and parietal areas (Peper et al., 2009a). Other HPG-axis hormones (testosterone, LH (Peper et al., 2009a) or FSH (unpublished data)) did not relate to cortical ...
The GPR54 Gene as a Regulator of Puberty
... hormone by the hypothalamus represents the first known step in the reproductive cascade — initiating pulsatile release of gonadotropins, gonadal secretion of sex steroids, pubertal development, and gametogenesis. Although the central role of gonadotropin-releasing hormone in the reproductive hierarc ...
... hormone by the hypothalamus represents the first known step in the reproductive cascade — initiating pulsatile release of gonadotropins, gonadal secretion of sex steroids, pubertal development, and gametogenesis. Although the central role of gonadotropin-releasing hormone in the reproductive hierarc ...
Anterior pituitary insufficiency
... Sheehan’s Syndrome (Panhypopituitarism) • Anterior Pituitary insufficiency commonly occurs in females with post-partum hemorrhage resulting in a clinical condition known as Sheehan’s Syndrome. • Anterior Pituitary which is highly vascular, gets enlarged during pregnancy. After childbirth, pituitary ...
... Sheehan’s Syndrome (Panhypopituitarism) • Anterior Pituitary insufficiency commonly occurs in females with post-partum hemorrhage resulting in a clinical condition known as Sheehan’s Syndrome. • Anterior Pituitary which is highly vascular, gets enlarged during pregnancy. After childbirth, pituitary ...
Glucocorticoids Regulate Pituitary Growth Hormone
... To determine whether the increased level of GHRH-R mRNA in response to dexamethasone treatment of dispersed anterior pituitary cells was caused by increased gene transcription or increased mRNA stability, the effects of dexamethasone were monitored in the presence and absence of the RNA polymerase i ...
... To determine whether the increased level of GHRH-R mRNA in response to dexamethasone treatment of dispersed anterior pituitary cells was caused by increased gene transcription or increased mRNA stability, the effects of dexamethasone were monitored in the presence and absence of the RNA polymerase i ...
hypthalamus and pitutary glands
... • The posterior lobe is richly endowed with fibers • The cell bodies from which these fibers arise are located in the hypothalamus • Secretory material synthesized in cell bodies in the hypothalamus is transported down the axons and stored in in the posterior lobe Dr. M. Alzaharna (2014) ...
... • The posterior lobe is richly endowed with fibers • The cell bodies from which these fibers arise are located in the hypothalamus • Secretory material synthesized in cell bodies in the hypothalamus is transported down the axons and stored in in the posterior lobe Dr. M. Alzaharna (2014) ...