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Hypothalamus and Pituitary
Hypothalamus and Pituitary

... hypothalamic releasing hormones is negative feedback exerted upon the hypothalamic-pituitary system by the hormones whose production are stimulated in the sequence. ...
Posterior pituitary gland
Posterior pituitary gland

... neurons in the hypothalamus synthesize and secrete the hypothalamic releasing and inhibitory hormones that control secretion of anterior pituitary  Neurons send their nerve fibers to the median eminence (extension of hypothalamic tissue into the pituitary stalk)  Hormones are secreted to the tissu ...
hypothalamo-Pituitary axis and regulatory mechanisms
hypothalamo-Pituitary axis and regulatory mechanisms

... secretion of anterior pituitary  Neurons send their nerve fibers to the median eminence (extension of hypothalamic tissue into the pituitary stalk)  Hormones are secreted to the tissue fluids, absorbed into the hypothalamic-hypophysial portal system and transported to the sinuses of the anterior p ...
paper
paper

... Research Program, Cellular Neurophysiology, Biomedical Research Center, National Institute on Drug Abuse, 251 Bayview Blvd, Baltimore, MD 21224, USA2. This work was funded by the Medical Research Council UK. C.M.-G. is in receipt of a CONACyT studentship. The pedunculopontine nucleus (PPN) is a brai ...
view - Scan. Vet. Press
view - Scan. Vet. Press

... secretion are primarily due to variations in GHRH secretion, whereas GHIH plays a relatively minor role. GH deficiency is not usually caused by a hypothalamic defect, but by malfunctioning of the pituitary cells that produce the hormone (clinical example, p. 264). In addition to GHRH, the peptide gh ...
Molecular and Cellular Endocrinology The goldfish (Carassius
Molecular and Cellular Endocrinology The goldfish (Carassius

... fields. In contrast to mammals, teleost fish do not have a median eminence; the anterior pituitary is innervated by numerous neuronal cell types and thus, pituitary hormone release is directly regulated. Here we briefly describe the neuroendocrine control of luteinizing hormone. Stimulation by gonadotr ...
The Pituitary Gland
The Pituitary Gland

... Luteinizing hormone (LH) - FSH in females: stimulates gonads/ reproduction growth of ovarian follicles in organs the ovary before the release of an egg from the follicle at ovulation • Responsible for ovulation ...
PITUITARY HORMONES AND THEIR HYPOTHALAMIC
PITUITARY HORMONES AND THEIR HYPOTHALAMIC

... a pulse generator at the arcuate nucleus, which becomes active at puberty (particularly during the sleep period).  GnRH acts on GnRH receptors located on gonadotropes (Gq  PLC  IP3  Ca2+). GnRH receptors are desensitized and down-regulated upon continued administration of GnRH or its analogs. ...
包爱民_下丘脑与垂体的内分泌功能
包爱民_下丘脑与垂体的内分泌功能

... – Stimulates the development of mammary glands and milk production • Growth hormone (GH or somatotropin) – Stimulates cell growth and replication through release of somatomedins or IGF • Growth-hormone releasing hormone (GH-RH) • Growth-hormone inhibiting hormone (GH-IH) ...
Practical information: Registration includes morning and afternoon
Practical information: Registration includes morning and afternoon

... Agonist docking in a GPR103 homology model: site-directed mutagenesis and structure-activity relationship studies 12h15 Isabelle Franceschini (INRA, Nouzilly, France) Development of kisspeptin neurons 12h45 Lunch ...
Detection of Indirect Androgen Doping with a GnRH Analog
Detection of Indirect Androgen Doping with a GnRH Analog

... This study evaluates the threat for sports doping of a class of hormones called gonadotrophin releasing hormone (GnRH) analogs. These are synthetic, small peptide superactive analogs of the natural hypothalamic hormone GnRH, a decapeptide which is a major regulator of the reproductive system. GnRH s ...
Hormonal Imbalances- Laura Knecht, MD
Hormonal Imbalances- Laura Knecht, MD

... • Secretes hormones-releasing and inhibitory effects on the pituitary gland ...
puberty
puberty

... enlargement in males. Axiliary and pubic hair follows along with other 2ndary sexual characteristics. • The maximum growth velocity occurs at 12 years. • The age of menarche has decreased over the last 3-4 decades due to improved nutrition, general health & life style. • Menarche marks the attainmen ...
Slide 1 - AccessPharmacy
Slide 1 - AccessPharmacy

... plexus in the median eminence. They are transported to the adenohypophysis by the hypothalamic–hypophyseal portal system, where they interact with specific populations of trophic hormone-secreting cells to govern the rate of release of preformed hormones, such as growth hormone (GH), somatotropic ho ...
GROWTH HORMONE
GROWTH HORMONE

... a cortisol response. In patients suspected of congenital adrenal hyperplasia, to identify 21-hydroxylase deficiency, 11-hydroxylase deficiency, and 3b-hydroxy-D5 steroid dehydrogenase deficiency, based on the steroids that accumulate in response to ACTH administration ...
Endocrine Physiology lecture 3
Endocrine Physiology lecture 3

...  Both are synthesized in the cell bodies of hypothalamic neurons  ADH: supraoptic nucleus  Oxytocin: paraventricular nucleus  Both are synthesized as preprohormones and processed into nonapeptides (nine amino acids).  They are released from the termini in response to an action potential which t ...
Endocrinology of reproduction I (Lecture 6 and 7 combined)
Endocrinology of reproduction I (Lecture 6 and 7 combined)

... • Secretes substances (hormones) into blood or lymph that affect cells elsewhere in the body • The secretion does not involve loss of tissue ...
An Introduction to the Hypothalamic–Pituitary–Gonadal Axis
An Introduction to the Hypothalamic–Pituitary–Gonadal Axis

... In response to stimulation from GnRH, these cells then produce LH and FSH, which enters into the blood stream. These two hormones have a significant role in communicating to the gonads. FSH and LH act primarily to activate the ovaries to produce estrogen and inhibin and to regulate the menstrual cy ...
thyroid and reproductive hormones
thyroid and reproductive hormones

... occurs in oviduct b) only about 0.001% of sperm make it that far; takes them an hour c) cleavage begins about 24 hours after fertilization ...
Endocrine Problems after Childhood Cancer: Precocious Puberty
Endocrine Problems after Childhood Cancer: Precocious Puberty

... - Ear or infratemporal region (midfacial area behind the cheekbones) • Female gender • Younger age at the time of cancer treatment Early puberty is also more common in overweight children. W H Y DO E S PR EC O CI O U S PU B E R TY H A PP EN ? The hypothalamus and pituitary gland may be damaged after ...
Airgas template - Morgan Community College :: Home
Airgas template - Morgan Community College :: Home

... Tertiary: abnormality in stimulation from the hypothalamus ...
Prolactin
Prolactin

... - Congenital hypogonadotropic hypogonadism in girls or boys can be caused by mutations in several different genes or combinations of genes .Family studies suggest that genes identified in association with absent puberty may cause delayed puberty and that there may be a genetic susceptibility to envi ...
Gynaecology – Dr. `Abeer – Lecture 1 – Physiology of Menstruation
Gynaecology – Dr. `Abeer – Lecture 1 – Physiology of Menstruation

... The hypothalamus in the forebrain secretes GnRH which controls of 2 important pituitary hormone secretion FSH (follicular stimulating hormone)& LH ( luteinising hormone) GnRH is of great importance in the menstrual cycle, its release occurs in a pulsatile fashion to stimulate LH & FSH, anything that ...
HAP - Unit 7 - Pituitary Glands - bushelman-hap
HAP - Unit 7 - Pituitary Glands - bushelman-hap

... • GH release is stimulated by the GHrH • Which act on somatomedins(IGF-1 somatomedinC) • Act to increase growth of cells, cartilage and protein metabolism. • GH release is inhibited by Somatostatins which are produced in the hypothalamus. • Secretion of somatostatins is stimulated by increased circu ...
DELAY PUBERTY
DELAY PUBERTY

... 2- permanent hypogonadotropic hypogonadism (characterized by low levels of luteinizing hormone and FSH owing to hypothalamic or pituitary disorders) 3-transienthypogonadotropic hypogonadism (functional hypogonadotropichypogonadism), in which pubertal delay is caused by delayed maturation of the HPG ...
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Kisspeptin

Kisspeptin (formerly known as metastin) is a protein that is encoded by the KISS1 gene in humans. Kisspeptin is a G-protein coupled receptor ligand for GPR54. Kiss1 was originally identified as a human metastasis suppressor gene that has the ability to suppress melanoma and breast cancer metastasis. Kisspeptin-GPR54 signaling has an important role in initiating secretion of gonadotropin-releasing hormone (GnRH) at puberty, the extent of which is an area of ongoing research. The release of gonadotropin-releasing hormone is due to an action on the anterior pituitary and also involves the release of luteinizing hormone (LH), and follicle stimulating hormone (FSH). These gonadotropic hormones lead to sexual maturation and gametogenesis. Disrupting GPR54 signaling can cause hypogonadotrophic hypogonadism in rodents and man. The Kiss1 gene is located on chromosome 1. It is transcribed in the brain, adrenal gland, and pancreas.
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