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puberty
puberty

... • Treat the underlying cause • GnRH analogue – Lupron depot ped, leuprolide acetate – Desensitizes the pituitary – Blocks LH and FSH secretion – Prevents continued sexual development for the duration of the treatment ...
Hormone Chart 2013 Blank
Hormone Chart 2013 Blank

... Releasing Hormone (GnRH) Growth Hormone Releasing Hormone ...
Hormone Chart
Hormone Chart

... adrenal cortex zona [aldosterone]*Reninglomerulosa Angiotensin pathway ...
TRH-TSH Releasing Hormone Stimulation Test
TRH-TSH Releasing Hormone Stimulation Test

... Note: GnRH is expensive and this test is rarely indicated on clinical grounds. An exception is in children with sexual precocity where an increased LH/FSH (of response to GnRH) is seen in central (true) sexual precocity. TRH testing has largely been replaced by sensitive plasma TSH assays for the di ...
Discuss the most common etiologies of secondary amenorrhea
Discuss the most common etiologies of secondary amenorrhea

... With secondary amenorrhea in addition to the absence of menses other manifestations may occur. These include infertility, vaginal atrophy, acne, vasomotor flushes, osteopenia, and hirsutism. Pregnancy must be ruled out prior to attempting to diagnose the cause of secondary amenorrhea. Once this has ...
DIRECTIONS: Each of the questions or incomplete statements
DIRECTIONS: Each of the questions or incomplete statements

... 21. The biologically active form of Vitamin D is produced in the (A) skin. (B) liver. (C) kidney. (D) intestine. (E) bone. 22. Elevation of plasma Ca to 12 mg would cause (A) inhibition of calcitonin secretion. (B) inhibition of PTH secretion. (C) an increase in plasma 1,25(OH)2D3. (D) increased neu ...
Adolescence and Puberty
Adolescence and Puberty

... functionality. In boys, the testis produce low levels of testosterone and in girls, the ovaries produce low levels of estrogen. There are also very low levels of GnRH from the hypothalamus and very low levels of FSH/LH from the anterior pituitary. In essence, there are hormones but at very low level ...
Endocrine Take-Home Quiz Answers
Endocrine Take-Home Quiz Answers

... 9. What is the difference between precocious puberty, premature thelarche and premature adrenarche? Precocious puberty – from the HPG axis and will follow typical pattern of development seen in puberty Premature thelarche – breast development only, diagnosis of exclusion, may be caused by exogenous ...
The anterior pituitary (adenohypophysis)
The anterior pituitary (adenohypophysis)

... The posterior pituitary is part of the brain; the anterior pituitary is not • In embryonic development, anterior pituitary arises from Rathke’s Pouch, an outgrowth of the pharynx. • Hypothalamic neurons communicate with the anterior pituitary by chemical signals called releasing factors and release ...
Endocrine Regulation
Endocrine Regulation

... o High levels of thyroxine cause the hypothalamus to release less TRH which then affects the levels of the other hormones. o Low levels of thyroxine cause hypothalamus to increase the release of TRH which the affects the levels of other hormones.  Reproduction: o Male: check out the diagram from pp ...
Endocrine System: The Hypothalamic–Pituitary Axis
Endocrine System: The Hypothalamic–Pituitary Axis

... Give an example of a hormone that has negative feedback mainly to the anterior pituitary. __________ Give an example of a hormone that has negative feedback to both the anterior pituitary and the ventral hypothalamus. ____________ ...
Quiz # 2 Friday, 21 September Answers
Quiz # 2 Friday, 21 September Answers

... Name on top back edge of this page. Quiz #2 Correct responses are in bold font. 1. Which of the following is synthesized and released by cells of the hypothalamus and reach its targets in the anterior pituitary by way of the hypothalamo-hypophyseal portal system? a) GnRH b) TSH c) Somatostatin d) do ...
Control of Follicle Stimulating Hormone (FSH) Secretion in the Male
Control of Follicle Stimulating Hormone (FSH) Secretion in the Male

... Mary's Hospital Medical School, London, W.2 Previous studies have indicated that the secretion of FSH in the male is controlled partly by androgens and partly by some non androgenic testicular hormone(s)-generally termed inhibin-which is related specifically to spermatogenesis. The chemical nature o ...
Biochemistry Objectives 44
Biochemistry Objectives 44

... Secretion control at the following levels: a. Physiological: secretion can be induced by three major mechanisms: increased plasma osmolarity sensed by osmoreceptors in the supraoptic nucleus, decreased volume sensed by volume receptors in the atrium, and decreased pressure sensed by baroreceptors in ...
Morphological and physiological interactions between GnRH3 and
Morphological and physiological interactions between GnRH3 and

... green and red fluorescent proteins, respectively. Using confocal microscopy, this animal model allows us to study the interactions of these two neuronal systems from larval stage (8 days post-fertilization, dpf) in vivo, as well as in the excised adult brain. We observed that both Hcrt and GnRH3 neu ...
Adolescence and Puberty
Adolescence and Puberty

... How do we know that the limbichypothalamic system is responsible for the immaturity of the reproductive system before puberty? 1. The immature gonads transplanted into an adult animal will mature immediately and demonstrate a normal reproductive function. 2. The pituitary, taken from a prepubertal ...
aaa - E-Learning/An-Najah National University
aaa - E-Learning/An-Najah National University

... prolactin production in the pituitary. High prolactin levels will inhibit gonadotrophin releasing hormone (GnRH) production in the hypothalamus, which is needed for LH and FSH production in the pituitary, needed for normal ovarian function thus causing amenorrhea. ...
Male Pseudo Hermaphrodite
Male Pseudo Hermaphrodite

... A) Mature spermatozoa are present at birth, but cannot be released until pubertyis reached. B)Spermatogenesis requires a temperature lower than internal body temperature. C)Spermatogenesis requires continuous release of gonadotropinreleasing hormone (GRH). D)Leydig cell secretion of testosterone re ...
Hormone Cycles - hrsbstaff.ednet.ns.ca
Hormone Cycles - hrsbstaff.ednet.ns.ca

... with mucus and blood vessels 2) secondary sex traits Lasts 10-14 days 5. High levels of estrogen in the blood cause 3) the pituitary gland to stop releasing FSH (Negative feedback) ...
Practice Questions Ch 8: 1. Calcitonin is secreted by A. the adrenal
Practice Questions Ch 8: 1. Calcitonin is secreted by A. the adrenal

... Practice Questions Ch 8: 1. Calcitonin is secreted by A. the adrenal medulla. B. the gonads. C. the thyroid gland. ...
Fertility disorders: a regulator in the brain. Press release, September
Fertility disorders: a regulator in the brain. Press release, September

... neuronal environment is an essential trigger for the entire cascade of events that activate reproductive functions. This research, published on 5 September 2011 in PNAS, may be the first step toward developing treatments for fertility disorders originating in the central nervous system (amenorrhea r ...
Title: A mathematical model of a GnRH neuron Abstract
Title: A mathematical model of a GnRH neuron Abstract

... Title: A mathematical model of a GnRH neuron Abstract: Gonadotropin-Releasing Hormone (GnRH) neurons are situated in the hypothalamus, and play a major role in the control of fertility and maturation, via their secretion of GnRH which causes the secretion of gonadotropin from the pituitary. As with ...
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Kisspeptin

Kisspeptin (formerly known as metastin) is a protein that is encoded by the KISS1 gene in humans. Kisspeptin is a G-protein coupled receptor ligand for GPR54. Kiss1 was originally identified as a human metastasis suppressor gene that has the ability to suppress melanoma and breast cancer metastasis. Kisspeptin-GPR54 signaling has an important role in initiating secretion of gonadotropin-releasing hormone (GnRH) at puberty, the extent of which is an area of ongoing research. The release of gonadotropin-releasing hormone is due to an action on the anterior pituitary and also involves the release of luteinizing hormone (LH), and follicle stimulating hormone (FSH). These gonadotropic hormones lead to sexual maturation and gametogenesis. Disrupting GPR54 signaling can cause hypogonadotrophic hypogonadism in rodents and man. The Kiss1 gene is located on chromosome 1. It is transcribed in the brain, adrenal gland, and pancreas.
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