1 - Medical Mastermind Community
... had not eaten for the last two days, due to a mild infection. Blood glucose and ketone body levels were found to be abnormally low, while circulating non-esterified fatty acids were greatly elevated. An abnormality in which one of the following enzymes is most ...
... had not eaten for the last two days, due to a mild infection. Blood glucose and ketone body levels were found to be abnormally low, while circulating non-esterified fatty acids were greatly elevated. An abnormality in which one of the following enzymes is most ...
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... 2. The Action of Plasmodesmata Callose Plasmodesmata (PDs) are dynamic symplasmic nanochannels that are localized in the plant cell wall and connect the cytoplasm spaces and endoplasmic reticulum compartments of adjacent cells [30–34]. PDs mediate the symplasmic movement of small molecules such as w ...
... 2. The Action of Plasmodesmata Callose Plasmodesmata (PDs) are dynamic symplasmic nanochannels that are localized in the plant cell wall and connect the cytoplasm spaces and endoplasmic reticulum compartments of adjacent cells [30–34]. PDs mediate the symplasmic movement of small molecules such as w ...
Faculty of Science, IUG
... Date:2/12 /2005 Name----------- & NO.----------Answer the following I- Sketch the titration curve, calculate pI and determine the regions of the buffer capacity of ASP. The pK values of its Alfa COOH, Alfa amino , and Beta COOH groups are 2.1, 9.2, and 3.9 respectively. (6pts). ...
... Date:2/12 /2005 Name----------- & NO.----------Answer the following I- Sketch the titration curve, calculate pI and determine the regions of the buffer capacity of ASP. The pK values of its Alfa COOH, Alfa amino , and Beta COOH groups are 2.1, 9.2, and 3.9 respectively. (6pts). ...
![Anti-ZAP-70 [pTyrpTyr315/319]Phosphospecific Antibody](http://s1.studyres.com/store/data/007988667_1-98a23e7ab9217d5db62ad8a049eacb7d-300x300.png)
Anti-ZAP-70 [pTyrpTyr315/319]Phosphospecific Antibody
... in ZAP-70 mediate activation and negative regulation of antigen receptor function. Mol. Cell. Biol. 16(9): 5026-5035. Peptide Competition and Phosphatase Treatment Lysates prepared from Jurkat cells left untreated (1) or treated with H2O2 (2-6) were resolved by SDS-PAGE on a 10% polyacrylamide gel a ...
... in ZAP-70 mediate activation and negative regulation of antigen receptor function. Mol. Cell. Biol. 16(9): 5026-5035. Peptide Competition and Phosphatase Treatment Lysates prepared from Jurkat cells left untreated (1) or treated with H2O2 (2-6) were resolved by SDS-PAGE on a 10% polyacrylamide gel a ...
Concept 3.1 Nucleic Acids Are Informational
... cannot be created or destroyed (energy of the universe is constant) • 2nd: every energy transfer of transformation makes the universe more disordered (every process increases the entropy of the universe) • Entropy: quantitative measure of disorder that is proportional to randomness (designated by th ...
... cannot be created or destroyed (energy of the universe is constant) • 2nd: every energy transfer of transformation makes the universe more disordered (every process increases the entropy of the universe) • Entropy: quantitative measure of disorder that is proportional to randomness (designated by th ...
Restless legs syndrome (RLS): Diagnosis
... D1 receptors modify the pain conduction only in L-DOPA-primed animals, not in the L-DOPA-naive animals. In the physiological condition, D1 receptors may slightly facilitate the conduction of pain sensation and this effect can be suppressed by an activation of D2 receptors After a withdrawal of LDOPA ...
... D1 receptors modify the pain conduction only in L-DOPA-primed animals, not in the L-DOPA-naive animals. In the physiological condition, D1 receptors may slightly facilitate the conduction of pain sensation and this effect can be suppressed by an activation of D2 receptors After a withdrawal of LDOPA ...
Protein oxidation and cellular homeostasis: Emphasis
... different enzymes: cytosolic Cu/Zn-SOD (SOD-1), mitochondrial Mn-SOD (SOD-2) and extracellular SOD (SOD-3) [38,39]. SOD-1 consists of two identical subunits and an active site containing copper and zinc atoms linked by a histidine residue. SOD-1 is constitutively expressed by all mammalian cells and ...
... different enzymes: cytosolic Cu/Zn-SOD (SOD-1), mitochondrial Mn-SOD (SOD-2) and extracellular SOD (SOD-3) [38,39]. SOD-1 consists of two identical subunits and an active site containing copper and zinc atoms linked by a histidine residue. SOD-1 is constitutively expressed by all mammalian cells and ...
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... prokaryotes and eukaryotes (2– 8). It is likely, therefore, that active extrusion systems play a crucial role in the cellular defense mechanism against incoming noxious compounds in many living organisms. It is of great interest and importance, therefore, to analyze the mechanism by which such unive ...
... prokaryotes and eukaryotes (2– 8). It is likely, therefore, that active extrusion systems play a crucial role in the cellular defense mechanism against incoming noxious compounds in many living organisms. It is of great interest and importance, therefore, to analyze the mechanism by which such unive ...
Slide 1
... The figure is adopted from the book: Devlin, T. M. (editor): Textbook of Biochemistry with Clinical Correlations, 4th ...
... The figure is adopted from the book: Devlin, T. M. (editor): Textbook of Biochemistry with Clinical Correlations, 4th ...
Biocatalysis - School of Chemical Sciences
... groups, minimized side reactions, easier separation, and fewer environmental problems. Other advantages, like high catalytic efficiency and mild operational conditions, are also very attractive in commercial applications. The characteristics of limited operating regions, substrate or product inhibiti ...
... groups, minimized side reactions, easier separation, and fewer environmental problems. Other advantages, like high catalytic efficiency and mild operational conditions, are also very attractive in commercial applications. The characteristics of limited operating regions, substrate or product inhibiti ...
Chapter 9 – Catalytic Strategies (So we`ve talked about enzymes
... (Many enzymes perform same reaction, Enz specific to substrate: Many enzymes work in a similar fashion and have structurally similar substrates. However, since enzymes have to be really specific to their substrate, often there are many enzymes that perform the same organic reaction but on a slightly ...
... (Many enzymes perform same reaction, Enz specific to substrate: Many enzymes work in a similar fashion and have structurally similar substrates. However, since enzymes have to be really specific to their substrate, often there are many enzymes that perform the same organic reaction but on a slightly ...
Fundamentals of Biochemistry 2/e
... 24 E1 proteins form dimers that associate with E2 core along the 12 edges. The 12 E3 proteins form dimers that attach to the 6 faces of E2 cube c) Combining a) and b) forms a 60 subunit complex ...
... 24 E1 proteins form dimers that associate with E2 core along the 12 edges. The 12 E3 proteins form dimers that attach to the 6 faces of E2 cube c) Combining a) and b) forms a 60 subunit complex ...
•High Boiling Point •High Specific Heat (Heat Capacity) •Very polar
... •Requires the sugar to be linear so that carbonyl is accessible (but remember that cyclic sugars can open up and then be reducing) These are reducing because an OH is attached to the anomeric ...
... •Requires the sugar to be linear so that carbonyl is accessible (but remember that cyclic sugars can open up and then be reducing) These are reducing because an OH is attached to the anomeric ...
ppt slides
... •Requires the sugar to be linear so that carbonyl is accessible (but remember that cyclic sugars can open up and then be reducing) These are reducing because an OH is attached to the anomeric ...
... •Requires the sugar to be linear so that carbonyl is accessible (but remember that cyclic sugars can open up and then be reducing) These are reducing because an OH is attached to the anomeric ...
A Quick Look at Biochemistry: Lipid Metabolism
... Cerebrosides are made by glycosidic linkage of the hydroxyl group of ceramide with one hexose molecule (glucose or galactose). In globosides one hexose molecule is substituted with dimmers. The molecular structures of gangliosides are similar to cerebrosides. It has at least three sugars, one of whi ...
... Cerebrosides are made by glycosidic linkage of the hydroxyl group of ceramide with one hexose molecule (glucose or galactose). In globosides one hexose molecule is substituted with dimmers. The molecular structures of gangliosides are similar to cerebrosides. It has at least three sugars, one of whi ...
Glycogen Metabolism Gluconeogenesis
... are associated on one hand with the inner surface of the plasma membrane, and on the other hand with membrane spanning receptor proteins called G-protein coupled receptors or GPCRs. • There are a number of different GPCRs; most commonly these are receptors for hormones or for some type of extracellu ...
... are associated on one hand with the inner surface of the plasma membrane, and on the other hand with membrane spanning receptor proteins called G-protein coupled receptors or GPCRs. • There are a number of different GPCRs; most commonly these are receptors for hormones or for some type of extracellu ...
The anti-adipogenic effect of vitexin is associated with regulation of
... since the 1990s. Specifically, the prevalence of obesity for men has increased from 10.5% in 1993–1996 to 32% in 2005–2008 (Fu et al., 2011). Glucose is the major carbohydrate available to most animal cells. Most of the carbon for fatty acid synthesis is derived from glucose. Glycolytic intermediate ...
... since the 1990s. Specifically, the prevalence of obesity for men has increased from 10.5% in 1993–1996 to 32% in 2005–2008 (Fu et al., 2011). Glucose is the major carbohydrate available to most animal cells. Most of the carbon for fatty acid synthesis is derived from glucose. Glycolytic intermediate ...
Coenzyme A and Acyl Carrier Protein
... which is directly involved in acyl transfer reactions. The adenosine 3’,5’-diphosphate moiety functions as a recognition site, increasing the affinity of CoA binding to enzymes. While acyl-dephospho-CoAs lacking the 3’-phosphate group on the ribose moiety have been detected in tissues, their functio ...
... which is directly involved in acyl transfer reactions. The adenosine 3’,5’-diphosphate moiety functions as a recognition site, increasing the affinity of CoA binding to enzymes. While acyl-dephospho-CoAs lacking the 3’-phosphate group on the ribose moiety have been detected in tissues, their functio ...
Chapter 7 - Macmillan Learning
... active site is the region where the reaction actually takes place. The conformational change in EnvZ exposes an active site that What does phosphorylation do to a protein? As discussed in was previously buried within the protein, so that EnvZ beSection 3.2, proteins can have both hydrophilic regions ...
... active site is the region where the reaction actually takes place. The conformational change in EnvZ exposes an active site that What does phosphorylation do to a protein? As discussed in was previously buried within the protein, so that EnvZ beSection 3.2, proteins can have both hydrophilic regions ...
Calcium Signaling
... AA-starved mTOR is distributed through the cytoplasm, and becomes localized to lysosomes rapidly on AA feeding ...
... AA-starved mTOR is distributed through the cytoplasm, and becomes localized to lysosomes rapidly on AA feeding ...
Chapter 7: Proteins
... Proteins help regulate acid-base balance in the blood pH measures acidity or alkalinity (base) – pH of 7 = neutral – pH<7 = acid – pH>7 = alkaline or base ...
... Proteins help regulate acid-base balance in the blood pH measures acidity or alkalinity (base) – pH of 7 = neutral – pH<7 = acid – pH>7 = alkaline or base ...
For lecture notes click here
... the triglycerides are broken down into fatty acids and monoglycerides. STEP 3: When IDLs reach the liver, additional triglycerides are removed and the protein content is altered. This process creates LDLs, which then returns to peripheral tissues to deliver cholesterol. STEP 4: LDLs leave the bloods ...
... the triglycerides are broken down into fatty acids and monoglycerides. STEP 3: When IDLs reach the liver, additional triglycerides are removed and the protein content is altered. This process creates LDLs, which then returns to peripheral tissues to deliver cholesterol. STEP 4: LDLs leave the bloods ...
Homeostatic Control of Metabolism
... Insulin Increases Glucose Transport • Required for resting skeletal muscle and adipose tissue • Moves GLUT-4 transporters to cell membrane • Exercising skeletal muscle does not require insulin for glucose uptake • In liver cells, indirect influence on glucose ...
... Insulin Increases Glucose Transport • Required for resting skeletal muscle and adipose tissue • Moves GLUT-4 transporters to cell membrane • Exercising skeletal muscle does not require insulin for glucose uptake • In liver cells, indirect influence on glucose ...
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... • Fats made from saturated fatty acids are called saturated fats, and are solid at room temperature • Most animal fats are saturated • Fats made from unsaturated fatty acids are called unsaturated fats or oils, and are liquid at room temperature • Plant fats and fish fats are usually unsaturated ...
... • Fats made from saturated fatty acids are called saturated fats, and are solid at room temperature • Most animal fats are saturated • Fats made from unsaturated fatty acids are called unsaturated fats or oils, and are liquid at room temperature • Plant fats and fish fats are usually unsaturated ...
Lipid signaling
Lipid signaling, broadly defined, refers to any biological signaling event involving a lipid messenger that binds a protein target, such as a receptor, kinase or phosphatase, which in turn mediate the effects of these lipids on specific cellular responses. Lipid signaling is thought to be qualitatively different from other classical signaling paradigms (such as monoamine neurotransmission) because lipids can freely diffuse through membranes (see osmosis.) One consequence of this is that lipid messengers cannot be stored in vesicles prior to release and so are often biosynthesized ""on demand"" at their intended site of action. As such, many lipid signaling molecules cannot circulate freely in solution but, rather, exist bound to special carrier proteins in serum.