R Is for Arginine
... concentrations may be limiting for NOS in specific subcellular locales. Moreover, the presence of endogenous competitive inhibitors of NOS (discussed below) may raise the effective intracellular arginine concentration needed for full enzyme activity. In any event, the action of NOS on l-arginine yie ...
... concentrations may be limiting for NOS in specific subcellular locales. Moreover, the presence of endogenous competitive inhibitors of NOS (discussed below) may raise the effective intracellular arginine concentration needed for full enzyme activity. In any event, the action of NOS on l-arginine yie ...
Page 1
... Cui et al., "The Permissive Effect of Zinc Deficiency on Uroguanylin and Inducible Nitric Oxide Synthase Gene Upregulation in Rat Intestine Induced by Interleukin la is Rapidly Reversed by Zinc Repletion", J. Nutri.,133(l): 51-56 (2003). Currie et al., "Guanylin: an endogenous activator of intestina ...
... Cui et al., "The Permissive Effect of Zinc Deficiency on Uroguanylin and Inducible Nitric Oxide Synthase Gene Upregulation in Rat Intestine Induced by Interleukin la is Rapidly Reversed by Zinc Repletion", J. Nutri.,133(l): 51-56 (2003). Currie et al., "Guanylin: an endogenous activator of intestina ...
An Introduction to Fluid, Electrolyte, and Acid–Base Balance
... • Physiological state resulting from abnormally low plasma pH • Acidemia plasma pH < 7.35 • Alkalosis • Physiological state resulting from abnormally high plasma pH • Alkalemia plasma pH > 7.45 ...
... • Physiological state resulting from abnormally low plasma pH • Acidemia plasma pH < 7.35 • Alkalosis • Physiological state resulting from abnormally high plasma pH • Alkalemia plasma pH > 7.45 ...
l-aspartate oxidase magnetic nanoparticles
... solution, O-acetyl urea is formed and, if it fails to react with an amine, undergoes to hydrolysis.22 Furthermore, an excess of EDC may promote unwanted polymerization due to the abundance of both amines and carboxylates on protein molecules leading to a protein-to-protein cross-linking.20 There is ...
... solution, O-acetyl urea is formed and, if it fails to react with an amine, undergoes to hydrolysis.22 Furthermore, an excess of EDC may promote unwanted polymerization due to the abundance of both amines and carboxylates on protein molecules leading to a protein-to-protein cross-linking.20 There is ...
Investigation of asparagine deamidation in a SOD1
... shift of -17 Da can be indicative of succinimide intermediate whose existence correlates with formation of Asp/isoAsp isomers and therefore may be useful in identification of the deamidation site. There are also two indirect proofs for the presence of isoAsp residue employed in this study: terminati ...
... shift of -17 Da can be indicative of succinimide intermediate whose existence correlates with formation of Asp/isoAsp isomers and therefore may be useful in identification of the deamidation site. There are also two indirect proofs for the presence of isoAsp residue employed in this study: terminati ...
Fat to the fire: the regulation of lipid oxidation
... the product of cardiac output ( Q) and proportion of the blood volume that is plasma [ Q plasma=Q (1 Hematocrit)], because FFA are not transported in red blood cells. Once at the myocyte, the rate of FFA uptake is dependent on many factors including transporter density, myocyte cytosolic protein bi ...
... the product of cardiac output ( Q) and proportion of the blood volume that is plasma [ Q plasma=Q (1 Hematocrit)], because FFA are not transported in red blood cells. Once at the myocyte, the rate of FFA uptake is dependent on many factors including transporter density, myocyte cytosolic protein bi ...
regulation of mammalian acetyl
... The isolation and characterization of the various phosphopeptides of ACC-α that can be phosphorylated by different protein kinases in vitro and in vivo (32, 35, 67) made it possible to identify the phosphorylation sites for specific protein kinases that control ACC activity under different physiolog ...
... The isolation and characterization of the various phosphopeptides of ACC-α that can be phosphorylated by different protein kinases in vitro and in vivo (32, 35, 67) made it possible to identify the phosphorylation sites for specific protein kinases that control ACC activity under different physiolog ...
1 Professor D.Sci. Judit Kosáry Nutritional biochemistry of the
... intermediates of their primary metabolic pathways. According to their role vitamins have diverse functions in the human metabolism. Polar (“water-soluble”) vitamins are precursors of reagents so-called coenzymes in metabolic organic chemical reactions. The water-soluble vitamins are vitamin C and a ...
... intermediates of their primary metabolic pathways. According to their role vitamins have diverse functions in the human metabolism. Polar (“water-soluble”) vitamins are precursors of reagents so-called coenzymes in metabolic organic chemical reactions. The water-soluble vitamins are vitamin C and a ...
Pharmacologyonline 3: 319-326 (2009) Sariri et al.
... from the present study, it is expected that other polyphenolic/flavonoid plant glycosides or ellagitannins, which can be easily extracted in hot water, may also contribute to the potent antioxidant activity of these extracts. Dorman et al. [16] have also demonstrated that radical scavenging activiti ...
... from the present study, it is expected that other polyphenolic/flavonoid plant glycosides or ellagitannins, which can be easily extracted in hot water, may also contribute to the potent antioxidant activity of these extracts. Dorman et al. [16] have also demonstrated that radical scavenging activiti ...
Fatty Acid Biosynthesis
... domain and the β-ketoacyl reductase domain. The β subunit contains the acetyl transferase domain, the malonyl transferase domain, the β-hydroxyacyl dehydrogenase domain and the enoyl reductase domain. The subunits are arranged in a head to tail fashion that allows the first domain of one subunit of ...
... domain and the β-ketoacyl reductase domain. The β subunit contains the acetyl transferase domain, the malonyl transferase domain, the β-hydroxyacyl dehydrogenase domain and the enoyl reductase domain. The subunits are arranged in a head to tail fashion that allows the first domain of one subunit of ...
Lactobacillus sanfrancisco a key sourdough lactic acid bacterium: a
... availability of specific amino acids and peptides excreted by yeasts. In alcoholic beverages, it has been shown that S. cerevisiae may release these nitrogen compounds either during growth (Thorne 1957, Suomalainen and Oura 1971) or as a consequence of an accelerated autolysis (Lyons and Rose 1977). ...
... availability of specific amino acids and peptides excreted by yeasts. In alcoholic beverages, it has been shown that S. cerevisiae may release these nitrogen compounds either during growth (Thorne 1957, Suomalainen and Oura 1971) or as a consequence of an accelerated autolysis (Lyons and Rose 1977). ...
rhizopus oryzae - Journal of Marine Science and Technology
... into chito-oligosaccharides with specific DP would substantially increase its practicability. Chitinases are enzymes that can hydrolyze chitin into chito-oligosaccharides. They were, thus far, found in most of the organisms such as animals, plants and microorganisms even those without chitin struc t ...
... into chito-oligosaccharides with specific DP would substantially increase its practicability. Chitinases are enzymes that can hydrolyze chitin into chito-oligosaccharides. They were, thus far, found in most of the organisms such as animals, plants and microorganisms even those without chitin struc t ...
Characterization of cytochrome P450
... grown in pots and maintained in the glass house. Leaf material was collected from 5 month old plants for RNA isolation. For wound induction plants were pricked at various parts with the help of syringe and forceps. Immediately after the wounding leaf samples were collected at 0 h, 1 h, 2 h and 4 h f ...
... grown in pots and maintained in the glass house. Leaf material was collected from 5 month old plants for RNA isolation. For wound induction plants were pricked at various parts with the help of syringe and forceps. Immediately after the wounding leaf samples were collected at 0 h, 1 h, 2 h and 4 h f ...
Design and Synthesis of RGD Mimetics as Potent Inhibitors of
... tested by altering the point of attachment at the backbone of the hydrophobic residue, without apparently changing its spatial orientation with respect to the two ionic sites (Scheme 6). The molecules were further simplified by using β-alanine as an aspartic acid mimic devoid of the α-carboxylic aci ...
... tested by altering the point of attachment at the backbone of the hydrophobic residue, without apparently changing its spatial orientation with respect to the two ionic sites (Scheme 6). The molecules were further simplified by using β-alanine as an aspartic acid mimic devoid of the α-carboxylic aci ...
Flavanoid-Biosynthesis
... There are two types of flavone synthases (FNS). Type I is oxoglutaratedependent and not very widespread in the plant kingdom. FNS II, however, has been observed in many plant species and is NADPH-dependent. Both introduce a double bond between C2 and C3 of the C-ring of flavanones. ...
... There are two types of flavone synthases (FNS). Type I is oxoglutaratedependent and not very widespread in the plant kingdom. FNS II, however, has been observed in many plant species and is NADPH-dependent. Both introduce a double bond between C2 and C3 of the C-ring of flavanones. ...
2. Citric acid cycle
... Fatty acids at coenzyme junction - becomes Acetyl CoA 2 carbons at a time via β-oxidation ...
... Fatty acids at coenzyme junction - becomes Acetyl CoA 2 carbons at a time via β-oxidation ...
AMINO ACID SEQUENCES AND EVOLUTIONARY RELATIONSHIPS
... Homologous structures, those structures believed to have a common origin but not necessarily a common function, provide some of the most significant evidence supporting the theory of evolution. For example, the forelimbs of vertebrates often have different functions and outward appearances, yet the ...
... Homologous structures, those structures believed to have a common origin but not necessarily a common function, provide some of the most significant evidence supporting the theory of evolution. For example, the forelimbs of vertebrates often have different functions and outward appearances, yet the ...
glucuronidation of opioids, carboxylic acid
... Kinetic Analysis of the Glucuronidation of Xenobiotics by Expressed UGT2B9. Apparent enantioselectivity was observed for the glucuronidation of (R/S)-ibuprofen, (R/S)-propanolol, and (1)/(2)menthol, but not for (R/S)-b-citronellol (tables 3 and 4). Kinetic analysis was conducted for some of these co ...
... Kinetic Analysis of the Glucuronidation of Xenobiotics by Expressed UGT2B9. Apparent enantioselectivity was observed for the glucuronidation of (R/S)-ibuprofen, (R/S)-propanolol, and (1)/(2)menthol, but not for (R/S)-b-citronellol (tables 3 and 4). Kinetic analysis was conducted for some of these co ...
1 Regulation of Substrate Oxidation Preferences in Muscle by the
... products of CPT-1 activity (13). In WT mice, fasting increases Cpt1b expression (Lange et al., 2007) and LC-AC (SI-Fig.3) (26), indicating increased CPT-1 activity (27). Taken together, our data suggest that adropin-deficiency and fasting induce similar changes in fatty acid oxidation in skeletal mu ...
... products of CPT-1 activity (13). In WT mice, fasting increases Cpt1b expression (Lange et al., 2007) and LC-AC (SI-Fig.3) (26), indicating increased CPT-1 activity (27). Taken together, our data suggest that adropin-deficiency and fasting induce similar changes in fatty acid oxidation in skeletal mu ...
Isoleucine Synthesis by Clostridium sporogenes from
... harvested during exponential growth (anaerobically, at 40000g, 20 min, 4 "C) and washed twice with 0.1 Mpotassium phosphate buffer, pH 7.4. The cells (0.27 g wet wt) were suspended in 2.0 ml of the buffer with 10 mM-Lisoleucine, 20 p c i L-[U-'4C]isoleucine (specific activity 360 pCi prilol-l ; 13.3 ...
... harvested during exponential growth (anaerobically, at 40000g, 20 min, 4 "C) and washed twice with 0.1 Mpotassium phosphate buffer, pH 7.4. The cells (0.27 g wet wt) were suspended in 2.0 ml of the buffer with 10 mM-Lisoleucine, 20 p c i L-[U-'4C]isoleucine (specific activity 360 pCi prilol-l ; 13.3 ...
Journal of Biological Chemistry
... have been shown so far (8, 12–18), metal ion-dependent ATPase activity by these transporters has not been clearly demonstrated. We have initiated biochemical studies of ZntA, as a prototype for the divalent soft metal transporting ATPases. Previously, we showed that ZntA confers resistance to Pb(II) ...
... have been shown so far (8, 12–18), metal ion-dependent ATPase activity by these transporters has not been clearly demonstrated. We have initiated biochemical studies of ZntA, as a prototype for the divalent soft metal transporting ATPases. Previously, we showed that ZntA confers resistance to Pb(II) ...
Genomics Insights esTs from seeds to Assist the selective Breeding
... germination and early seedling growth. In this sense, fatty acids act as molecules of energy storage that are used to “fuel” the cell when other energy sources are not available. During seed maturation, hexose phosphates from photo-assimilates are massively metabolized through the glycolytic pathway ...
... germination and early seedling growth. In this sense, fatty acids act as molecules of energy storage that are used to “fuel” the cell when other energy sources are not available. During seed maturation, hexose phosphates from photo-assimilates are massively metabolized through the glycolytic pathway ...
Peroxisome Proliferator-Activated Receptor Activation is
... the relationship between PPARα and other metabolic pathways has only recently gained attention. Involvement in amino acid metabolism has been demonstrated [19,20], and fibrates, which are specific PPARα ligands have consistently been associated with elevated plasma tHcy [21], as well as being associ ...
... the relationship between PPARα and other metabolic pathways has only recently gained attention. Involvement in amino acid metabolism has been demonstrated [19,20], and fibrates, which are specific PPARα ligands have consistently been associated with elevated plasma tHcy [21], as well as being associ ...
Synthesis and Pharmacological Evaluation of
... Cancer, a disease of worldwide importance, is a group of diseases characterized by uncontrolled growth and spread of abnormal cells. It is now generally accepted that a neoplastic transformation is related to genes alteration or oncogene activation, allowing progress in the development of new treatm ...
... Cancer, a disease of worldwide importance, is a group of diseases characterized by uncontrolled growth and spread of abnormal cells. It is now generally accepted that a neoplastic transformation is related to genes alteration or oncogene activation, allowing progress in the development of new treatm ...
Fatty acid synthase inhibitors of phenolic constituents
... compounds 7 and 9, respectively, indicating that the phenolic hydroxyl groups are required for the activity. The more phenolic hydroxyl groups in the compound, the higher activity. However, the acute function loss of compounds 4 and 7 compared to c-mangostin (3) and compound (8) suggested that the n ...
... compounds 7 and 9, respectively, indicating that the phenolic hydroxyl groups are required for the activity. The more phenolic hydroxyl groups in the compound, the higher activity. However, the acute function loss of compounds 4 and 7 compared to c-mangostin (3) and compound (8) suggested that the n ...