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Biology DNA, RNA and Protein Review sheet To prepare for the test, go back and review: Chapter 12.1-12.3 Notes Chapter 13.1-13.3 Labs Class handouts Other 1. Identify the three main experiments leading to our acceptance of DNA as the molecule of inheritance. Include: a. Scientist(s) b. Organism(s) and/or viruses used c. Overview of experimental design/procedures d. One sentence conclusion 2. What type of macromolecule is DNA? 3. DNA is composed of what monomer? 4. What are the three units to the above monomer? 5. Identify the 4 different types of nitrogenous bases? 6. Nitrogenous bases can be sorted into two groups. Name the groups and explain how they are classified. 7. What units make up the backbone of DNA? 8. Explain how the information Watson and Crick acquired from Rosalind Franklin and Chargaff was used to determine the structure of DNA. 9. Explain complementary base pairing and the bases involved. 10. What hold base pairs together and how many? 11. Explain the steps involved in replication. 12. What is a replication bubble? 13. What enzyme is involved in attaching nucleotides to form DNA? 14. Explain the relationship between a gene, genotype, phenotype and protein. 15. Compare and contrast DNA and mRNA. 16. Identify and describe the three types of RNA. 17. Why are three nucleotides needed for one codon? 18. For transcription and translation: a. Summarize in one sentence. b. What “materials” are needed? c. Identify the step. d. Where does it take place? 19. Explain how mRNA is edited/spliced before it leaves the nucleus. 20. Define mutation. 21. What are two main classes of mutations? 22. What is a point mutation? 23. What is the difference between a silent mutation and an expressed mutation? 24. Explain how insertions and deletions are frameshift mutations. 25. What is a mutagen? Give an example.