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Transcript
The Cycle of Infection
Infection and Disease
Classifications
• 4 types1. Endogenous- it originates w/in
2. Exogenous- it originates outside the body
3. Nosocomial- the infection is one that is
acquired by an individual in a health care
facility which are transmitted by health care
workers to the patient.
4. Opportunistic- means the infections are those
that occur when the body defenses are weak.
Also classified as Aerobic or
Anaerobic
• Aerobic- means the organism requires
oxygen to live
• Anaerobic- means it lives and reproduces in
the absence of oxygen.
The Chain of Infection
Infectious Agent
The Chain of Infection
Infectious Agent
Reservoir Host
The Chain of Infection
Infectious Agent
Reservoir Host
Portal of Exit
The Chain of Infection
Infectious Agent
Reservoir Host
Portal of Exit
Mode of Transmission
The Chain of Infection
Infectious Agent
Reservoir Host
Portal of Exit
Portal of Entry
Mode of Transmission
The Chain of Infection
Infectious Agent
Reservoir Host
Susceptible Host
Portal of Exit
Portal of Entry
Mode of Transmission
As healthcare
professionals, it is
important to
understand two
things about
infection:
1.the various ways infection can
be transmitted
2. the ways the infection chain
can be broken
There are six
links
in the chain of
infection :
1st - The Infectious Agent
-any disease-causing
microorganism
(pathogen)
2nd - The Reservoir Host
-the organism in which the
infectious microbes reside
What are “Carrier Hosts”
Hosts that do not show any outward signs or
symptoms of a disease but are still capable
of transmitting the disease are known as
carriers.
3rd - The Portal of Exit
-route of escape of the pathogen
from the reservoir.
Examples: respiratory
secretions, blood
exposure, breaks in
skin
4th - The Route of
Transmission
-method by which the pathogen
gets from the reservoir to the
new host
Transmission may occur through:
direct contact
air
insects
5th - The Portal of Entry
-route through which the
pathogen enters its new host
Respiratory System
Gastrointestinal System
Urinary & Reproductive Tracts
Breaks in Protective Skin Barrier
6th - The Susceptible Host
-the organism that accepts the
pathogen
The support of pathogen life & its
reproduction depend on the degree
of the host’s resistance.
Organisms with strong immune
systems are better able to fend off
pathogens.
Organisms with weakened immune
systems are more vulnerable to the
support & reproduction of pathogens.
How to interrupt the chain of
infection:
-The essential part of patient care &
self-protection.
1. Pathogen Identification
-identification of infectious
agent & appropriate treatment
2. Asepsis & Hygiene
-potential hosts &
carriers must practice
asepsis & maintain
proper personal hygiene
3. Control Portals of Exit
-healthcare personnel must
practice standard precautions:
4. Prevent a Route of
Transmission
-prevent direct or indirect contact
by:
1. Proper handwashing
2. Disinfection & sterilization techniques
3. Isolation of infected patients
4. Not working when contagious
(Control body secretions & wash
hands according to protocol.)
5. Protect Portal of Entry
-Health professionals must make
sure that ports of entry are not
subjected to pathogens.
(nose, mouth, eyes, urinary tract,
open wounds, etc.)
6. Recognition of Susceptible
Host
-health professionals must recognize
& protect high-risk patients
•Cancer Patients
•AIDS Patients
•Transplant Patients
•Infant & Elderly
Patients
Remember--breaking the chain of
infection is the responsibility
of each health professional.
Microorganisms and Disease
• A. Microorganism: an organism that is too small to be
seen by the human eye
 1. Fungi: simple plants such as molds and yeasts, some of which
cause disease
 2. Protozoa: the only group of microorganisms classified as an
animal
 3. Virus: microorganisms that are so small they cannot be seen
with an ordinary light microscope. They are not destroyed by
antibiotics.
•
4. Bacteria: microorganisms first seen under the microscope by Antoni van
Leeuwenhoek in 1693. The classification is determined by the shape of the bacteria
and whether it grows with or without oxygen. Only a few bacteria, such as
staphylococcus and streptococcus cause disease.
 a. Aerobic bacteria: live and multiply in the presence of oxygen
 b. Anaerobic bacteria: live and multiply without oxygen
 c. Cocci: round bacteria
 • Staphylococci: round bacteria in clusters like grapes; cause boils, impetigo,
and osteomyelitis
 • Streptococci: round bacteria arranged in chains; cause rheumatic fever,
streptococcal pneumonia, and scarlet fever
 • Diplococci: round bacteria arranged in pairs; cause gonorrhea and
meningitis
 d. Bacilla: rod shaped bacteria
 e. Spirilla: shaped like spirals
 5. Rickettsiae: smaller than bacteria, barely visible under light microscope; cause
typhus, Rocky Mountain spotted fever
• B. Pathogen: a disease causing
microorganism
Asepsis is the absence of
infection
• A. Medical asepsis: practices and techniques that are designed to
protect individuals from the spread of disease
 1. Antiseptic: substances that inhibit the growth of bacteria.
Some of these substances can be used on the skin.
 2. Disinfectant: substances or practices that cannot be used on
the skin. This includes chemicals and boiling.
 3. Sterile: absence of all microorganisms
• B. Surgical asepsis: the use of sterile technique to handle
equipment, maintain sterile fields, change dressings and dispose of
contaminated materials without introducing harmful microorganisms
Epidemiology-tracing the occurrence of health related
events in society
• A. Epidemiologist is a person who specializes in the
study of outbreaks of diseases within a population group
 1. Endemic: refers to the ongoing presence of a disease within a
population, group, or area. For example, the common cold is
always present within a population.
 2. Epidemic: is a sudden and widespread outbreak of a disease
within a population, group or area. For example a sudden wide
spread outbreak of measles is an epidemic.
 3. Pandemic: refers to an outbreak of a disease occurring over a
large geographic area, possibly worldwide. For example, AIDS is
pandemic.