Download Microbiology

MICROBIOLOGY
I.
Name of the unit offering the course: Department of Microbiology
II.
Head of the unit/Course coordinator: prof. dr hab. Eugenia Gospodarek-Komkowska/ dr
Aleksander Deptuła
III.
2nd year, number of hours: 75
IV.
Form of classes: lectures: 37, tutorials: 38
V.
Form of crediting: Exam,
VI.
Number of ECTS points: 6
VII.
Aim of the course:
Lectures
The aim is to present the information on:

classification of microorganisms,

bacterial and fungal cell structure and physiology,

pathogen and host interactions,

antimicrobial agents and chemotherapy of infections,

aetiology, epidemiology, pathogenesis, clinical signs and treatment of viral, bacterial and fungal
infections.
Tutorials:

introduction to microbial physiology, morphology, and their biological properties, as well as hostpathogen interactions,

presentation of disinfection and sterilization methods and prevention of infectious diseases,

introduction to methods used in the microbiological investigation,
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presentation of indications for microbiological investigations – due to diagnostical and
epidemiological needs,

presentation of rules for taking samples for microbiological investigations, proper way of
transporting of clinical samples,

familiarization with microbiological investigations and interpretation of its results, and proper use
of their results in the therapeutic process,

introduction to the principles of antimicrobial therapy.
VIII.
Topics of lectures / tutorials:
Lectures:

The history of microbiology.

The general microbial characteristics (Procaryota, Eucaryota, Virales).

The taxonomy. Classification and identification of microorganisms.

The microbial morphology. Anatomical structures – their structure, function and significance in
identification of microorganisms. Chemical composition of microorganism.

The microbial physiology. Growth condition, metabolism, reproduction, genetics and genetical
variability of microorganisms.

The microbial pathogenicity, infectivity and toxicity. The pathogenesis of infections.
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The influence of physical factors and chemical substancies on microbial biological properties.
Disinfection and sterilization. The overview of disinfectants and antiseptics and their mechanisms
of action. The resistance of microorganisms to disinfectants.

The antimicrobials – classification, groups overwiev, mechanisms of action. Antimicrobial
resistance mechanisms. Methods of antimicrobial resistance testing. The general rules of
antimicrobial treatment.

The basis of infective immunology. Immunological methods used in microbiological investigations.
Immunoprophylaxis and immunotreatment. Vaccines. Immunity sera and immunoglobulines.

The bacteriology. Overwiev of bacteria pathogenic for human.
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The virology.
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The mycology.
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Respiratory tract infections.

Urinary tract infections.

Gastrointestinal tract infections and foodborne diseases.

Sexually transmitted diseases. Intra-uterine and neonatal infections.
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Skin, mucosal and eye infections.

Surgical infections.
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Infections caused by anaerobic bacteria.
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Central nervous system infections.
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Bloodstream infections.
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The microbiological investigation of autopsical samples.
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The diagnostics of infections. Sampling, storage conditions and transporting of clinical specimens
for microbiological investigations.

Hospital acquired infections. Infection prevention and control, epidemiological investigation,
microorganisms typing methods – the role of microbiologist.
Laboratory classes:
Winter semester:
1. The organization of classes. Microbiological laboratory safety rules. The Procaryota cell structure.
Microscopy techniques.
2. Staining methods and microbial morphology. Methods used for microbiological investigations.
3. Methods used for microbiological investigations (culture techniques, serological and molecular
biology investigations).
4. Methods for antimicrobial sensitivity testing. General rules of antimicrobial therapy.
5. Methods for detection of antimicrobial resistance and interpreting of antimicrobial sensitivity
testing results.
6. Methods used for microbiological investigation of staff and hospital environment. Hospital
hygiene.
7. Characteristics of yeasts, moulds and dermatophytes. Methods used for mycological investigation.
8. Test. Methods for sampling and transporting clinical samples for microbiological investigation. The
human normal flora.
Summer semester:
1. Respiratory tract infections.
2.
Urinary tract infections.
3. Central nervous system infection. Eye infections.
4. Surgical site infections, skin and soft tissue infections.
5. Genital tract infections. Perinatal infections.
6. Gastrointestinal tract infections.
7. Infection caused by anaerobic bacteria.
8. Blodstream infections.
9. Opportunistic infections.
10. Healthcare associated infections.
11. Test. Interpretation of microbiological investigation results.
IX.
Self-study topics:
----------X.
Booklist:
Murray PR, Rosenthal KS, Pfaller MA: Medical microbiology. MOSBY Elsevier, 2009
XI.
Detailed list of required practical skills and confirmation of completing: