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Download Anti-CYP24A1 antibody ab109632 Product datasheet 1 Image Overview
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Product datasheet Anti-CYP24A1 antibody ab109632 1 Image Overview Product name Anti-CYP24A1 antibody Description Goat polyclonal to CYP24A1 Tested applications WB Species reactivity Reacts with: Rat, Human Immunogen Synthetic peptide: C-RKYDIQATDN , corresponding to internal sequence amino acids 481-490 of Human CYP24A1 (NP_000773.2) Run BLAST with Positive control Run BLAST with Human liver lysate Properties Form Liquid Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. Storage buffer Preservative: 0.02% Sodium Azide Constituents: 0.5% BSA, Tris buffered saline, pH 7.3 Purity Immunogen affinity purified Purification notes Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Clonality Polyclonal Isotype IgG Applications Our Abpromise guarantee covers the use of ab109632 in the following tested applications. The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. Application WB Abreviews Notes Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 59 kDa). 1 Target Function Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23lactone as end product. Sequence similarities Belongs to the cytochrome P450 family. Cellular localization Mitochondrion. Anti-CYP24A1 antibody images Anti-CYP24A1 antibody (ab109632) at 0.1 µg/ml + Human liver lysate in RIPA buffer at 35 µg developed using the ECL technique Predicted band size : 59 kDa Observed band size : 50 kDa Western blot - CYP24A1 antibody (ab109632) Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE" Our Abpromise to you: Quality guaranteed and expert technical support Replacement or refund for products not performing as stated on the datasheet Valid for 12 months from date of delivery Response to your inquiry within 24 hours We provide support in Chinese, English, French, German, Japanese and Spanish Extensive multi-media technical resources to help you We investigate all quality concerns to ensure our products perform to the highest standards If the product does not perform as described on this datasheet, we will offer a refund or replacement. For full details of the Abpromise, please visit http://www.abcam.com/abpromise or contact our technical team. Terms and conditions Guarantee only valid for products bought direct from Abcam or one of our authorized distributors 2
