Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Tissue engineering wikipedia , lookup
Endomembrane system wikipedia , lookup
Cell encapsulation wikipedia , lookup
Extracellular matrix wikipedia , lookup
Cellular differentiation wikipedia , lookup
Cell growth wikipedia , lookup
Cytokinesis wikipedia , lookup
Cell culture wikipedia , lookup
BME 273 Senior Design Project Group 25 Scientific Design BioMEMs cell culture device Cell Culture Design Cross Section Materials Polydimethlysiloxane (PDMS) Negative Resist (SU-8) Silicon Wafers MEMS laboratory 8 mm masks Platinum (working electrodes) Silver (reference Ag/AgCl electrodes) Fabrication Steps Lay down SU-8 on silicon wafer, expose using mask, and develop lower region for cell insertion and perfusion. Cast PDMS replica of master Lay down SU-8 on silicon wafer, expose using mask, and develop upper region for pneumatic control of cell insertion channels. Cast PDMS replica of master and then lay over top of lower region Business Strategy Developing a strategy to present to venture capitalists Components Market & Demand Environment Technological Environment Competitive Environment Economic & Policy Environment Strategic Implications of Innovation Success Factors Technology Intelligence (Contacts) Product Development Financing Main Focus Points Nano-scale Simulate in vivo better than current methods Scale up the number of cell cultures per experiment Automated experiments Cost efficiency Portable experimentation? Applications Replace conventional cell culture techniques Scale up Reduce number of lab technicians cost efficient Drug development Monitor cells before & after drug Drug Companies Pfizer Johnson & Johnson GlaxoSmithKline Novartis Merck Eli Lilly Abbott Laboratories http://finance.yahoo.com Project Schedule – Microsoft Project Project Schedule – Gant Chart References http://finance.yahoo.com Fabrication of miniature Clark oxygen sensor integrated with microstructure Ching-Chou Wu, Tomoyuki Yasukawa, Hitoshi Shiku, Tomokazu Matsue http://www.bme.vanderbilt.edu/srdesign/2005/group25/272_sdart icle.pdf A BioMEMS Review: MEMS Technology for Physiologically Integrated Devices AMY C. RICHARDS GRAYSON, REBECCA S. SHAWGO, AUDREY M. JOHNSON, NOLAN T. FLYNN, YAWEN LI, MICHAEL J. CIMA, AND ROBERT LANGER http://www.bme.vanderbilt.edu/srdesign/2005/group25/BioMEMS _review.pdf