Download Life Sciences Research Office LSRO, Inc.

The Status and Future of
Integrative and Organ Systems
Sciences
October 20 – 21, 2002
Bethesda, MD
Sponsored by:
Co-sponsors:
APS and ASPET
Burroughs Wellcome Fund
Merck Research Laboratories
Definitions
• Reductionist approaches are aimed at identifying
molecular and cellular events, studied in purified
form or in isolated systems and including
genomics, proteomics, biochemistry and cell
biology
• Integrative and Organ Systems approaches are
aimed at understanding how intact biological
systems function at the level of whole animals,
organs and organ systems (but not in the clinic).
Life Sciences Research Office
(LSRO)
Michael Falk
Executive Director
Mission
To benefit society by evaluating biological
information and scientific opinion for the
public and private sectors
Steering Committee
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James R. Bloedel
Joseph R. Haywood
D. Euan MacIntyre
Peter C. Preusch
James H. Woods
Edward J. Zambraski
HGS Annual Reports
• Founded in 1992 – leader in the discovery of human
and microbial genes
• 1995 “success in turning our leadership in gene
discovery into leadership in the creation of proprietary
pharmaceutical products”
• 1997 “year of change for our company, as we began to
implement clinical development of our own drugs”
• 1998 “significant progress in its ongoing transition to
a fully integrated biopharmaceutical company that
discovers, develops, manufactures and markets”
• 2000 “genomics” found only once