Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Slide ()
Document related concepts
no text concepts found
Transcript
Regulation of gastric acid and pepsin secretion by soluble mediators and neural input. Gastrin is released from G cells in the antrum in response to gastrin releasing peptide (GRP) and travels through the circulation to influence the activity of ECL cells and parietal cells. ECL cells release histamine, which also acts on parietal cells. Acetylcholine (ACh), released from nerves, is an agonist for ECL cells, chief cells, and parietal cells. Other specific agonists of the chief cell are not well understood. Gastrin release is negatively regulated by luminal acidity via the release of somatostatin from antral D cells. P, pepsinogen. (Adapted from Barrett KE: Gastrointestinal Physiology. McGraw-Hill, 2006.) Source: Chapter 25. Overview of Gastrointestinal Function & Regulation, Ganong's Review of Medical Physiology, 24e Citation: Barrett KE, Boitano S, Barman SM, Brooks HL. Ganong's Review of Medical Physiology, 24e; 2012 Available at: http://mhmedical.com/ Accessed: May 13, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved
