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NOVA Online Cancer Tutorial-How Cancer Grows Name:_____________ Date:__________ Period:____ Standard: BI5. a. Students know the general structures and functions of DNA, RNA, and protein. Objective(s): SWBAT… Explain the origin of new cells. Describe the structure and function of DNA. Directions: Open the following link: http://www.pbs.org/wgbh/nova/cancer/grow_flash.html If the flashplayer does not work then use the following link: http://www.pbs.org/wgbh/nova/cancer/grow_nf01.html Read each section of tutorial and answer the questions below. Click next to move on to the next section. A.)Introduction: 1. What are carcinomas? 2. Where do carcinomas originate? B.)DNA of a Normal: 1. What is the role of DNA in cells? 2. Why is it important that the DNA be the same in all the cells? C.)Mutation of DNA: 1. How is the mutated DNA different than the “normal” DNA? 2. How can mutations be caused? D.)Genetically Altered Cell/First Mutation: 1. Which process do body cells use to replicate? 2. How do mutated cells replicated differently than normal cells? E.)Spread and Second Mutation: 1. What do the mutated cells do to the normal cells? 2. How do the mutated cells end up with more than one mutant genes? F.)Third/Fourth Mutations: 1. How do mutations cause tumors to develop? 2. In comparison to normal cells why do cancers grow more rapidly? G.)Angiogenesis: 1. What is angiogenesis? 2. How big is the tumor and how many cells is it made of? H.)Invasion and Dispersal: 1. How does the tumor spread to different parts of the body? 2. How many tumor cells can a tumor the size of a gram send out per day? I.)Metastasis: 1. How do tumors form new colonies? 2. Why can does metastasis lead to death?