Download 13543-44768-1-SP - Saudi Medical Journal

Dear editor ,
Here within enclosed is our paper for consideration to be published
on “The Saudi Medical Journal”. The further information about the
paper is in the following:
The Title: Predictors of Upgraded and Upstaged Prostate
Cancer in Patients with Gleason score 6 or 7 at Biopsy
The Authors: Shuai Liu1, Jiaqi Wang1, Kejia Ding2,Jiaju Lv3,
Sentai Ding4, Jiming Zhao 5,Dongbin Bi6
1
ShandongProvincial Hospital Affiliated to Shandong University, Jina
n 250021, P.R. China;
1
2
Shandong University, Jinan 250012, P.R. China;
ShandongProvincial Hospital Affiliated to Shandong University, Jina
n 250021, P.R. China;
3
ShandongProvincial Hospital Affiliated to Shandong University, Jina
n 250021, P.R. China;
4
ShandongProvincial Hospital Affiliated to Shandong University, Jina
n 250021, P.R. China;
5
ShandongProvincial Hospital Affiliated to Shandong University, Jina
n 250021, P.R. China;
6
ShandongProvincial Hospital Affiliated to Shandong University, Jina
n 250021, P.R. China;
Brief introduction of our article: Prostate cancer (PCa) usually
has extended natural history, with a significant controversy
concerning the optimal treatment. One of the most important factors
influencing treatment choice is the Gleason score (GS) from the initial
prostate biopsy. Determination of whether a patient should be actively
treated for low-risk prostate cancer remains controversial, as multiple
studies have reported that a considerable proportion of men qualifying
for active surveillance (AS) have aggressive tumor features at RP.
The objective of this study was to examine the pathologic outcomes in
men with GS 6 or 7 PCa who underwent RP and to identify
preoperative factors including biopsy features that impact the
incidence of upgrading and upstaging. These results in turn may aid
in therapeutic management of patients with GS6 or7 tumor at initial
diagnosis.
The authors claim that none of the material in the paper has been
published or is under consideration for publication elsewhere,and We
declare that we have no conflict of interest. My work is suitable to your
journal.
I am the corresponding author and my address and other
information is as follows,
Address: DongBin Bi.Department of Urology, Provincial Hospital
affiliated to Shandong University, 324 Jingwu Street, Jinan, China,
250021.
E-mail: [email protected]
Education background：Doctor
Thank you very much for consideration!
Sincerely Yours,
DongBin Bi