Download AED Side Effects - North Pacific Epilepsy Research

Medications to Treat Seizures:
Side Effects
General principles
Medications are the most
common way to prevent
seizures. All drugs cause some
type of side effect. The best drug
for you will provide a balance
between no seizures and
minimal side effects. Antiepileptic drugs (AEDs) have two
types of side effects: those related to the drug
(idiosyncratic); and those related to the dose of
the drug. Idiosyncratic reactions are most likely
to occur within the first 12 weeks of starting the
drug.
Side effects that you need to report to the
doctor:
Your doctor may periodically order certain tests
to monitor your liver enzymes, white blood
count, or platelets.
Dose-dependent side effects
AEDs are usually started at low doses and
increased slowly. As your medication levels
increase, you may begin to notice other side
effects. It is possible to stop these side effects by
changing the dose of your medication. Reducing
your dose may cause you to have more seizures.
You should not change the dose without
discussing this with your doctor. Some of these
side effects include: drowsiness, dizziness,
nausea, changes in coordination or balance, and/
or changes in mood or thinking.
Medication plan
• A painful rash. Especially if you notice
blisters or peeling of the skin around your
eyes, mouth, or genitals. Often occurs
with fever and sore throat.
• Excessive bleeding
• Abdominal pain and yellowing skin or
eyes
• Fever or unusual infections
You and the doctor will come up with a
medication plan. It is very important for you to
follow this plan. If you stop or change your
medications suddenly, then you are at risk for
having a seizure. When you start a new drug,
you should keep a side effect diary. Bring this
diary in to your next visit. If you do not notice
any side effects, then this is not necessary.
Other side effects (rare) related to the
drug
If you have trouble taking your medications,
then consider having a family member remind
you and make it a
part of your routine.
For example, take
your pills when you
brush your teeth.
Using a weekly pill
Other side effects may be related to the drug.
These include:
• Decreased levels of white blood cells or
platelets. This could make you more
prone to infections or bleeding.
• Liver failure
NW Pacific Epilepsy Research
Providence St. Vincent Medical Center Epilepsy Program
April 2006
box may also be a good idea.
Reference
Shorvon, S. (2000). Handbook of Epilepsy Treatment. Malden,
MA: Blackwell Science Ltd.
NW Pacific Epilepsy Research
Providence St. Vincent Medical Center Epilepsy Program
April 2006