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Transcript
POSTDOCTORAL POSITIONS ARE AVAILABLE IMMEDIATELY IN
THE LABORATORY OF MOLECULAR CONTROL OF
MORPHOGENESIS AND TUMOR PROGRESSION
Professor Jean Paul Thiery, Principal Investigator, Institute of Molecular Cell biology (IMCB),
A*STAR, Singapore.
Applicants should have a Ph.D. degree and have at least one first author peer-reviewed paper in a well
recognized international journal.
A strong background in biophysics or in cell molecular developmental biology is required.
Several projects are ongoing in the laboratory on the mechanochemistry of cell adhesion and on
mechanisms driving epithelial-mesenchymal transition. The laboratory explores mechanisms regulating
cell migration in vivo using new transgenic models targeting the neural crest. Induction and branching
morphogenesis is analyzed in the mammary gland in vitro and in vivo with recently developed transgenic
models. The laboratory is also engaged in a large screen of oncogenes and tumor suppressor genes
involved in cancer progression, taking advantage of a new extremely powerful method of insertional
mutagenesis based on transposition. There is a particular focus on breast carcinoma basal cell subtypes.
IMCB is the largest of the A*STAR Institutes in Singapore, located on the new campus of Biopolis. More
than 5000 scientists are now working on this multidisciplinary campus, close to the National University of
Singapore. Core facilities include very large computing facilities, bioinformatics and most advanced
oncogenomic, bioengineering and nanotechnology platforms. X-ray crystallography, large scale
production of cells and proteins, DNA sequencing, NMR, mass spectrometry, flow cytometry, video,
TIRF, FRAP, FRET and confocal microscopy are all available at IMCB. IMCB houses one of the most
advanced zebrafish facilities in the world, and has direct access to one of largest animal facilities.
Biomedical science has become a top priority of the Republic of Singapore, which is now already widely
considered to be the new eldorado for scientists. Research is fully supported by government funding
making everyday laboratory life much easier than in many other countries.
Singapore is a small city state of 4.5 million, on an island at the southern tip of Malaysia. It is a
multicultural and multiracial society. Changi Airport is considered to be the best airport worldwide in
term of effectiveness and connections. The cost of living is relatively low (compared to countries in
Europe and North America); income tax is one of the lowest in the world. Many international schools and
universities now operate in Singapore.
Long term employment prospects are good. A scientific career in Singapore, following a postdoctoral
position, can be easily envisioned due to the very rapid expansion of academic institutions. The private
sector is flourishing in Singapore and offers multiple opportunities for senior positions.
Interested individuals should send their application, CV and name and address of three referees to:
Professor Jean Paul Thiery
Institute of Molecular and Cell Biology
Proteos, 61 Biopolis Drive,
138673 SINGAPORE
Tel 6565869621
Mail: [email protected]
Web: http://www.imcb.a-star.edu.sg